The central basis of motivation: intracranial self-stimulation studies.

Studies of Neuronal Activity Related to Self-Stimulation .. Olds . Rolls • Segal . Views on Self-Stimulation and Existing Functional Neural Systems .

[1]  J. W. Papez.  A PROPOSED MECHANISM OF EMOTION , 1937 .

[2]  J. Brobeck,et al.  Hypothalamic Control of Food Intake in Rats and Cats * , 1951, The Yale journal of biology and medicine.

[3]  James L Olds,et al.  Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. , 1954, Journal of comparative and physiological psychology.

[4]  K. Pribram,et al.  FUNCTIONS OF THE “OLFACTORY BRAIN” , 1954, Annals of the New York Academy of Sciences.

[5]  M. Sidman,et al.  Reward schedules and behavior maintained by intracranial self-stimulation. , 1955, Science.

[6]  J. Brobeck.  NEURAL REGULATION OF FOOD INTAKE , 1955, Annals of the New York Academy of Sciences.

[7]  James L Olds.  Runway and maze behavior controlled by basomedial forebrain stimulation in the rat. , 1956, Journal of comparative and physiological psychology.

[8]  B. Andersson,et al.  The elicitation of a drinking motor conditioned reaction by electrical stimulation of the hypothalamic drinking area in the goat. , 1957, Acta physiologica Scandinavica.

[9]  J. Brobeck.  Neural Control of Hunger, Appetite, and Satiety ** , 1957, The Yale journal of biology and medicine.

[10]  W. R. Hess,et al.  The functional organization of the diencephalon , 1957 .

[11]  G. Bower,et al.  Rewarding and punishing effects from stimulating the same place in the rat's brain. , 1958, Journal of Comparative and Physiological Psychology.

[12]  N. Miller.  Central stimulation and other new approaches to motivation and reward. , 1958 .

[13]  James L Olds.  Satiation effects in self-stimulation of the brain. , 1958, Journal of comparative and physiological psychology.

[14]  W. W. Roberts.  Both rewarding and punishing effects from stimulation of posterior hypothalamus of cat with same electrode at same intensity. , 1958, Journal of comparative and physiological psychology.

[15]  L STEIN,et al.  Self-Regulation of Brain-Stimulating Current Intensity in the Rat , 1959, Science.

[16]  James L Olds,et al.  Resistance to extinction following cranial self-stimulation. , 1959, Journal of comparative and physiological psychology.

[17]  J. Brady,et al.  Some neural and behavioral correlates of electrical self-stimulation of the limbic system. , 1959, Journal of the experimental analysis of behavior.

[18]  B. Andersson,et al.  A study of central regulation of rumination and reticulo-ruminal motility. , 1959, Acta physiologica Scandinavica.

[19]  J. Brady,et al.  Some effects of limbic system selfstimulation upon conditioned emotional behavior. , 1960, Journal of comparative and physiological psychology.

[20]  D. A. Brodie,et al.  Rewarding Properties of Intracranial Stimulation , 1960, Science.

[21]  James L Olds,et al.  Reinforcing effect of brain stimuation on runway performance as a function of interval between trials. , 1960, Journal of comparative and physiological psychology.

[22]  J. Deutsch.  The structural basis of behavior , 1960 .

[23]  C. Dobrzecka,et al.  Relationship between Feeding and Satiation Centers of the Hypothalamus , 1960, Science.

[24]  S. Glickman.  Reinforcing properties of arousal. , 1960, Journal of comparative and physiological psychology.

[25]  James L Olds,et al.  Effects of chlorpromazine, meprobamate, pentobarbital and morphine on self-stimulation. , 1960, The Journal of pharmacology and experimental therapeutics.

[26]  James L Olds,et al.  Topographic organization of hypothalamic self-stimulation functions. , 1960, Journal of comparative and physiological psychology.

[27]  B. Anand.  Nervous Regulation of Food Intake , 1961 .

[28]  P. Morgane,et al.  Medial forebrain bundle and “feeding centers” of the hypothalamus , 1961, The Journal of comparative neurology.

[29]  L. Stein.  Effects and interactions of imipramine, chlorpromazine, reserpine and amphetamine on self-stimulation: possible neurophysiological basis of depression. , 1961, Recent advances in biological psychiatry.

[30]  C. I. Howarth,et al.  Drive Decay: The Cause of Fast "Extinction" of Habits Learned for Brain Stimulation , 1962, Science.

[31]  J. Lilly,et al.  Operant conditioning of the bottlenose dolphin with electrical stimulation of the brain. , 1962 .

[32]  P. Teitelbaum,et al.  Hypothalamic Control of Feeding and Self-Stimulation , 1962, Science.

[33]  James L Olds,et al.  Identical "Feeding" and "Rewarding" Systems in the Lateral Hypothalamus of Rats , 1962, Science.

[34]  G. Thieme,et al.  FLUORESCENCE OF CATECHOL AMINES AND RELATED COMPOUNDS CONDENSED WITH FORMALDEHYDE , 1962 .

[35]  James L Olds,et al.  Approach-escape interactions in rat brain. , 1962, The American journal of physiology.

[36]  J. Olds.  Hypothalamic substrates of reward. , 1962, Physiological reviews.

[37]  N. Spear.  Comparison of the reinforcing effect of brain stimulation on Skinner box, runway, and maze performance. , 1962, Journal of comparative and physiological psychology.

[38]  C. I. Howarth,et al.  SOME TESTS OF A THEORY OF INTRACRANIAL SELF-STIMULATION. , 1963, Psychological review.

[39]  Herberg Lj.  Seminal ejaculation following positively reinforcing electrical stimulation of the rat hypothalamus. , 1963 .

[40]  R. Heath,et al.  Intracranial Self-Stimulation in Man , 1963, Science.

[41]  T. Hawkins,et al.  Test of Deutsch's Drive-Decay Theory of Rewarding Self-Stimulation of the Brain , 1963, Science.

[42]  D. Justesen,et al.  Self-stimulation of the caudate nucleus by instrumentally naive cats. , 1963, Journal of comparative and physiological psychology.

[43]  J A Deutsch,et al.  Learning and electrical self-stimulation of the brain. , 1963, Journal of theoretical biology.

[44]  James L Olds,et al.  Approach‐avoidance analysis of rat diencephalon , 1963, The Journal of comparative neurology.

[45]  James L Olds,et al.  AMYGDALOID STIMULATION AND OPERANT REINFORCEMENT IN THE RAT. , 1963, Journal of comparative and physiological psychology.

[46]  M. Wetzel.  Self-stimulation aftereffcts and runway performance in the rat. , 1963, Journal of comparative and physiological psychology.

[47]  Herberg Lj.  Determinants of extinction in electrical self-stimulation. , 1963 .

[48]  P. Stark,et al.  EFFECTS OF CHOLINERGIC DRUGS ON HYPOTHALAMIC SELF-STIMULATION RESPONSE RATES OF DOGS. , 1963, The American journal of physiology.

[49]  Deutsch Ja.  BEHAVIORAL MEASUREMENT OF THE NEURAL REFRACTORY PERIOD AND ITS APPLICATION TO INTRACRANIAL SELF-STIMULATION. , 1964 .

[50]  C. Gallistel.  ELECTRICAL SELF-STIMULATION AND ITS THEORETICAL IMPLICATIONS. , 1964, Psychological bulletin.

[51]  E. Valenstein,et al.  Interaction of Positive and Negative Reinforcing Neural Systems , 1964, Science.

[52]  L. Stein.  SELF-STIMULATION OF THE BRAIN AND THE CENTRAL STIMULANT ACTION OF AMPHETAMINE. , 1964, Federation proceedings.

[53]  L. Vereczkey,et al.  Hypothalamic Motivational Processes as Reflected by their Hippocampal Electrical Correlates , 1965, Science.

[54]  G. G. Ball,et al.  Intracranial stimulation as an avoidance or escape response , 1965 .

[55]  W. Hodos.  MOTIVATIONAL PROPERTIES OF LONG DURATIONS OF REWARDING BRAIN STIMULATION. , 1965, Journal of comparative and physiological psychology.

[56]  A. Routtenberg,et al.  Effects of the availability of rewarding septal and hypothalamic stimulation on bar pressing for food under conditions of deprivation. , 1965, Journal of comparative and physiological psychology.

[57]  H. L. Knook.  The fibre-connections of the forebrain , 1965 .

[58]  K. Fuxe,et al.  EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. IV. DISTRIBUTION OF MONOAMINE NERVE TERMINALS IN THE CENTRAL NERVOUS SYSTEM. , 1965, Acta physiologica Scandinavica. Supplementum.

[59]  T. Hawkins,et al.  BRAIN STIMULATION AS A REINFORCER: INTERMITTENT SCHEDULES. , 1965, Journal of the experimental analysis of behavior.

[60]  E. Valenstein.  The Anatomical Locus of Reinforcement , 1966 .

[61]  C. Gallistel.  Motivating effects in self-stimulation. , 1966, Journal of comparative and physiological psychology.

[62]  A. Bruner.  Facilitation of classical conditioning in rabbits by reinforcing brain stimulation , 1966 .

[63]  E. Valenstein,et al.  Medial forebrain bundle-lateral hypothalamic area and reinforcing brain stimulation. , 1966, The American journal of physiology.

[64]  B. Hoebel,et al.  "Copulation-Reward Site" in the Posterior Hypothalamus , 1966, Science.

[65]  James L Olds,et al.  Self-stimulation of hippocampus in rats. , 1966, Journal of comparative and physiological psychology.

[66]  M. Berkley,et al.  Extinction responding following ICS and food reinforcement , 1966 .

[67]  G. Mogenson,et al.  Drinking and self-stimulation with electrical stimulation of the lateral hypothalamus , 1966 .

[68]  F. W. Ninteman,et al.  Hypothalamic self-stimulation: its suppression by blockade of norepinephrine biosynthesis and reinstatement by methamphetamine. , 1966, Life sciences.

[69]  S. Glickman,et al.  A biological theory of reinforcement. , 1967, Psychological review.

[70]  J. Deutsch,et al.  Hunger and extinction in intracranial self-stimulation. , 1967, Journal of comparative and physiological psychology.

[71]  Intracranial stimulation and natural reward: Differential effects of trial spacing , 1967 .

[72]  R. E. Keesey,et al.  Use of progressive fixed-ratio procedures in the assessment of intracranial reinforcement. , 1968, Journal of the experimental analysis of behavior.

[73]  A. Routtenberg.  The two-arousal hypothesis: reticular formation and limbic system. , 1968, Psychological review.

[74]  J. Panksepp,et al.  The effect of intertrial interval on running performance for ESB , 1968 .

[75]  W. H. Morse,et al.  Determinants of the specificity of behavioral effects of drugs. , 1968, Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie.

[76]  J. Panksepp,et al.  The effect of lever retraction on resistance to extinction of a response rewarded with electrical stimulation of the brain , 1968 .

[77]  E. Valenstein,et al.  Modification of Motivated Behavior Elicited by Electrical Stimulation of the Hypothalamus , 1968, Science.

[78]  J. W. Kling,et al.  Discrimination of brightness differences by rats with food or brain-stimulation reinforcement. , 1968, Journal of the experimental analysis of behavior.

[79]  J. Panksepp,et al.  An incentive model of rewarding brain stimulation. , 1969, Psychological review.

[80]  O. E. Millhouse.  A Golgi study of the desending medial forebrain bundle. , 1969, Brain research.

[81]  G. Mogenson.  Water deprivation and excessive water intake during self-stimulation☆ , 1969 .

[82]  James L Olds,et al.  Effects of lesions in medial forebrain bundle on self-stimulation behavior. , 1969, The American journal of physiology.

[83]  L. Stein,et al.  Release of norepinephrine from hypothalamus and amygdala by rewarding medial forebrain bundle stimulation and amphetamine. , 1969, Journal of comparative and physiological psychology.

[84]  B. Poschel.  Mapping of rat brain for self-stimulation under monoamine oxidase blockade , 1969 .

[85]  S. Snyder,et al.  Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas. , 1969, The Journal of pharmacology and experimental therapeutics.

[86]  B. Hoebel.  FEEDING AND SELF‐STIMULATION * , 1969, Annals of the New York Academy of Sciences.

[87]  L Stein,et al.  Facilitation of Brain Self-Stimulation by Central Administration of Norepinephrine , 1969, Science.

[88]  James L Olds.  The central nervous system and the reinforcement of behavior. , 1969, The American psychologist.

[89]  G. Mogenson,et al.  Self-stimulation of the olfactory bulb , 1969 .

[90]  A. Routtenberg,et al.  Brainstem pathways of reward. , 1969, Journal of comparative and physiological psychology.

[91]  E. Valenstein.  Behavior Elicited by Hypothalamic Stimulation , 1969 .

[92]  Margules Dl.  Noradrenergic rather than serotonergic basis of reward in the dorsal tegmentum. , 1969 .

[93]  A. Caggiula.  Analysis of the copulation-reward properties of posterior hypothalamic stimulation in male rats. , 1970, Journal of comparative and physiological psychology.

[94]  E. Boyd,et al.  Effect of some brain lesions on septal intracranial self-stimulation in the rat. , 1967, The American journal of physiology.

[95]  S. Roll.  Intracranial Self-Stimulation and Wakefulness: Effect of Manipulating Ambient Brain Catecholamines , 1970, Science.

[96]  A. Routtenberg,et al.  Forebrain pathways of reward in Rattus norvegicus. , 1971, Journal of comparative and physiological psychology.

[97]  G. Mogenson.  Stability and modification of consummatory behaviors elicited by electrical stimulation of the hypothalamus. , 1971, Physiology & behavior.

[98]  A. Routtenberg,et al.  Lateral hypothalamic self-stimulation pathways in Rattus norvegicus. , 1971, Physiology & behavior.

[99]  U. Ungerstedt.  Stereotaxic mapping of the monoamine pathways in the rat brain. , 1971, Acta physiologica Scandinavica. Supplementum.

[100]  G. Breese,et al.  Effect of 6‐hydroxydopamine on electrical self stimulation of the brain , 1971, British journal of pharmacology.

[101]  M. Hamburg.  Hypothalamic unit activity and eating behavior. , 1971, The American journal of physiology.

[102]  James L Olds,et al.  Unit activity during self-stimulation behavior. , 1971, Journal of neurophysiology.

[103]  K. Taylor,et al.  Specific noradrenergic neurones destroyed by 6-hydroxydopamine injection into newborn rats. , 1972, Nature: New biology.

[104]  A Routtenberg,et al.  Self-stimulation in the frontal cortex of Rattus norvegicus. , 1972, Behavioral biology.

[105]  T. Crow.  Catecholamine-containing neurones and electrical self-stimulation: 1. a review of some data , 1972, Psychological Medicine.

[106]  James L Olds,et al.  Differential development of conditioned unit changes in thalamus and cortex of rat. , 1972, Journal of neurophysiology.

[107]  J F Disterhoft,et al.  Learning centers of rat brain mapped by measuring latencies of conditioned unit responses. , 1972, Journal of neurophysiology.

[108]  T. Crow,et al.  A map of the rat mesencephalon for electrical self-stimulation. , 1972, Brain research.

[109]  A. Routtenberg.  Intracranial Self-Stimulation Pathways as Substrate for Stimulus-Response Integration , 1973 .

[110]  L. Stein,et al.  Amphetamine and noradrenergic reward pathways , 1973 .

[111]  A. E. Fisher,et al.  Neurochemical mediation of reward: a significant role for dopamine? , 1973, Pharmacology, biochemistry, and behavior.

[112]  Anthony G. Phillips,et al.  Dopaminergic and Noradrenergic Substrates of Positive Reinforcement: Differential Effects of d- and l-Amphetamine , 1973, Science.

[113]  S. Snyder,et al.  Regional Distribution of Opiate Receptor Binding in Monkey and Human Brain , 1973, Nature.

[114]  T. Crow,et al.  Catecholamine-containing neurones and electrical self-stimulation: 2. A theoretical interpretation and some psychiatric implications , 1973, Psychological Medicine.

[115]  L. Stein,et al.  Self-stimulation of noradrenergic cell group (A6) in locus coeruleus of rats. , 1973, Journal of comparative and physiological psychology.

[116]  B. Berger,et al.  Histochemical confirmation for dopaminergic innervation of the rat cerebral cortex after destruction of the noradrenergic ascending pathways. , 1974, Brain research.

[117]  A. Routtenberg,et al.  Ascending monoamine-containing fiber pathways related to intracranial self-stimulation: histochemical fluorescence study. , 1974, Brain research.

[118]  L. Stein,et al.  Self-stimulation in the mesencephalic trajectory of the ventral noradrenergic bundle. , 1974, Brain research.

[119]  O. Lindvall,et al.  The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxylic acid fluorescence method. , 1974, Acta physiologica Scandinavica. Supplementum.

[120]  D. German,et al.  Catecholamine systems as the neural substrate for intracranial self-stimulation: a hypothesis. , 1974, Brain research.

[121]  R. Carey,et al.  Differential effects of d-amphetamine on fixed ratio 30 performance maintained by food versus brain stimulation reinforcement. , 1974, Pharmacology, biochemistry, and behavior.

[122]  Telencephalic distribution of terminals of brainstem norepinephrine neurons , 1974 .

[123]  T. Hökfelt,et al.  The origin of the dopamine nerve terminals in limbic and frontal cortex. Evidence for meso-cortico dopamine neurons. , 1974, Brain research.

[124]  G. Koob,et al.  Electrical self-stimulation of single and multiple loci: long term observations. , 1974, Physiology & behavior.

[125]  R. Moore,et al.  Catecholamine‐containing neurons of the nucleus locus coeruleus in the cat , 1974, The Journal of comparative neurology.

[126]  D. Jacobowitz,et al.  Topographic atlas of catecholamine and acetylcholinesterase‐containing neurons in the rat brain. I. Forebrain (telencephalon, diencephalon) , 1974, The Journal of comparative neurology.

[127]  J. Belluzzi,et al.  Substantia nigra self-stimulation: dependence on noradrenergic reward pathways. , 1975, Behavioral biology.

[128]  H. Morris,et al.  Identification of two related pentapeptides from the brain with potent opiate agonist activity , 1975, Nature.

[129]  R. Bodnar,et al.  Comparison of behaviors elicited by electrical brain stimulation in dorsal brain stem and hypothalamus of rats. , 1975, Journal of comparative and physiological psychology.

[130]  M. Le Moal,et al.  Self-stimulation in the dorsal pontine tegmentum in the rat. , 1975, Behavioral biology.

[131]  S. Snyder,et al.  An endogenous morphine-like factor in mammalian brain. , 1975, Life sciences.

[132]  M. Olds.  Effects of intraventricular 6-hydroxydopamine and replacement therapy with norepinephrine, dopamine, and serotonin on self-stimulation in diencephalic and mesencephalic regions in the rat , 1975, Brain Research.

[133]  R. Moore.  Monoamine Neurons Innervating the Hippocampal Formation and Septum: Organization and Response to Injury , 1975 .

[134]  K. Franklin,et al.  Self-stimulation and noradrenaline: Evidence that inhibition of synthesis abolishes responding only if the ‘reserve’ pool is dispersed first , 1975, Brain Research.

[135]  L. D. Reid,et al.  Intracranial self-stimulation effects along the route of the nigro-striatal bundle , 1975, Brain Research.

[136]  E. Rolls,et al.  Differential effects on self-stimulation and motor behaviour produced by microintracranial injections of a dopamine-receptor blocking agent , 1975, Neuroscience Letters.

[137]  E. Rolls.  The brain and reward , 1975 .

[138]  J. Huston,et al.  Influence of 6-hydroxydopamine injections in the substantia nigra on lateral hypothalamic reinforcement , 1975, Neuroscience Letters.

[139]  A. Phillips,et al.  Effects of amphetamine isomers and neuroleptics on self-stimulation from the nucleus accumbens and dorsal nor-adrenergenic bundle , 1975, Brain Research.

[140]  D. Amaral,et al.  Locus coeruleus and intracranial self-stimulation: a cautionary note. , 1975, Behavioral biology.

[141]  A. Phillips,et al.  Evidence that self-stimulation of the region of the locus coeruleus in rats does not depend upon noradrenergic projections to telencephalon , 1976, Brain Research.

[142]  A. Phillips,et al.  Dopaminergic substrates of intracranial self-stimulation in the caudate-putamen , 1976, Brain Research.

[143]  Regional changes in [3H]-noradrenaline uptake, catecholamines and catecholamine synthetic and catabolic enzymes in rat brain following neonatal 6-hydroxydopamine treatment. , 1976, Medical biology.

[144]  F. Bloom,et al.  The action of norepinephrine in the rat hippocampus. III. Hippocampal cellular responses to locus coeruleus stimulation in the awake rat , 1976, Brain Research.

[145]  A. Wauquier.  Brain-stimulation Reward , 1976 .

[146]  E. Rolls,et al.  Effects of Dopamine-Receptor Blockade on Self-Stimulation in the Monkey I , 1975 .

[147]  B. Berger,et al.  Dopaminergic innervation of the rat prefrontal cortex: A fluorescence histochemical study , 1976, Brain Research.

[148]  A. Routtenberg.  Self stimulation pathways: Origins and terminations - a three stage technique , 1976 .

[149]  R. Norgren.  Taste pathways to hypothalamus and amygdala , 1976, The Journal of comparative neurology.

[150]  M. Olds.  Effectiveness of morphine and ineffectiveness of diazepam and phenobarbital on the motivational properties of hypothalamic self-stimulation behaviour , 1976, Neuropharmacology.

[151]  F. Bloom,et al.  The action of norepinephrine in the rat hippocampus. IV. The effects of locus coeruleus stimulation on evoked hippocampal unit activity , 1976, Brain Research.

[152]  R. Wise,et al.  Pimozide-induced extinction of intracranial self-stimulation: response patterns rule out motor or performance deficits , 1976, Brain Research.

[153]  A. Routtenberg,et al.  Brain stem self-stimulation attenuated by lesions of medial forebrain bundle but not by lesions of locus coeruleus or the caudal ventral norepinephrine bundle , 1976, Brain Research.

[154]  Barbara E. Jones,et al.  Ascending projections of the locus coeruleus in the rat. I. axonal transport in central noradrenaline neurons , 1977, Brain Research.

[155]  M. Kuhar,et al.  Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon , 1977, Brain Research.

[156]  L. Stein,et al.  Enkephalin may mediate euphoria and drive-reduction reward , 1977, Nature.

[157]  P. Milner,et al.  Schedule control of behavior reinforced by electrical stimulation of the brain. , 1977, Science.

[158]  R. Clavier,et al.  On the role of ascending catecholaminergic projections in intracranial self-stimulation of the substantia nigra , 1977, Brain Research.

[159]  G. Uhl,et al.  Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[160]  Barbara E. Jones,et al.  Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study , 1977, Brain Research.

[161]  M. Kuhar,et al.  Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla , 1977, Brain Research.

[162]  F. Bloom,et al.  Neuronal and neurochemical substrates of reinforcement. , 1977, Neurosciences Research Program bulletin.

[163]  C. Kornetsky,et al.  Morphine lowering of self-stimulation thresholds: lack of tolerance with long-term administration. , 1977, Science.

[164]  Food and intracranial stimulation responding suppressed with regular-interval shock. , 1977, Journal of the experimental analysis of behavior.

[165]  P. Milner.  Theories of Reinforcement, Drive, and Motivation , 1977 .

[166]  M. Kuhar,et al.  Autoradiographic localization of opiate receptors in rat brain. II. The brain stem , 1977, Brain Research.

[167]  H. Fibiger.  Drugs and reinforcement mechanisms: a critical review of the catecholamine theory. , 1978, Annual review of pharmacology and toxicology.

[168]  L. Stein.  Brain endorphins: possible mediators of pleasure and reward. , 1978, Neurosciences Research Program bulletin.

[169]  A. Phillips,et al.  The role of dopamine in maintaining intracranial self-stimulation in the ventral tegmentum, nucleus accumbens, and medial prefrontal cortex. , 1978, Canadian journal of psychology.

[170]  Ralph N. Adams,et al.  Dopamine and norepinephrine enhancement in discrete rat brain regions following neonatal 6-hydroxydopamine treatment , 1978, Brain Research.

[171]  P. Milner,et al.  An investigation of responding on schedules of electrical brain-stimulation reinforcement. , 1978, Canadian journal of psychology.

[172]  F. Mora.  The neurochemical substrates of prefrontal cortex self-stimulation: a review and an interpretation of some recent data. , 1978, Life sciences.

[173]  R. Wise.  Catecholamine theories of reward: A critical review , 1978, Brain Research.

[174]  L. F. Kromer,et al.  The Organization of Central Catecholamine Neuron Systems , 1978 .

[175]  P. Cuatrecasas,et al.  Immunohistochemical localization of enkephalin in rat brain and spinal cord , 1978, The Journal of comparative neurology.

[176]  A. Routtenberg.  The reward system of the brain. , 1978, Scientific American.

[177]  G. Mogenson,et al.  Evidence for a role for dopamine in self-stimulation of the nucleus accumbens of the rat. , 1978, Canadian journal of psychology.

[178]  W. Nauta,et al.  Crossroads of Limbic and Striatal Circuitry: Hypothalamo-Nigral Connections , 1978 .

[179]  R. Bodnar,et al.  Morphine and intracranial self-stimulation in the hypothalamus and dorsal brainstem: differential effects of dose, time and site. , 1979, The International journal of neuroscience.

[180]  A. Routtenberg.  Participation of brain stimulation reward substrates in memory: anatomical and biochemical evidence. , 1979, Federation proceedings.

[181]  F E Bloom,et al.  Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. , 1979, Annual review of neuroscience.

[182]  B. Hoebel.  Hypothalamic self-stimulation and stimulation escape in relation to feeding and mating. , 1979, Federation proceedings.

[183]  Functional, anatomical and pharmacological aspects of central motivational systems: a tribute to James Olds. Introduction. , 1979, Federation proceedings.

[184]  C. Kornetsky,et al.  Effects of morphine on intracranial self-stimulation to various brain stem loci , 1979, Brain Research.

[185]  J. Bockaert,et al.  Effects of intraventricular injection of 6-hydroxydopamine in the developing kitten. II. On the central monoaminergic innervation , 1979, Brain Research.

[186]  S. P. Grossman.  The biology of motivation. , 1979, Annual review of psychology.

[187]  M. Olds.  Hypothalamic substrate for the positive reinforcing properties of morphine in the rat , 1979, Brain Research.