SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models
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You Won Lee | S. Heo | S. Lim | B. Cho | H. Kim | Ji Min Lee | C. Kim | K. Pyo | M. Hong | San-Duk Yang | H. K. Lee | Jung-Ho Kim | M. Yun | Sungho Park | Do Hee Kim | Chun-Bong Synn | Jae Hwan Kim | J. Cho | J. Yun | H. Choi | Sangbin Lim | B. Ahn | Y. Choi | Sung Eun Kim | Chaewon Park | Y. Byeon | Dong Kwon Kim | Young Seob Kim | Wongeun Lee | E. Lee | S. S. Lee | H. Jo | Seul Lee | Min‐Hwan Kim | H. R. Kim
[1] Sung-Bae Kim,et al. Pembrolizumab plus chemotherapy as neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer: results from the phase 1b open-label, multicohort KEYNOTE-173 study. , 2020, Annals of oncology : official journal of the European Society for Medical Oncology.
[2] Yu‐quan Wei,et al. AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications , 2019, Molecular Cancer.
[3] P. thor Straten,et al. TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting , 2019, Cancer Immunology, Immunotherapy.
[4] Jae Cheol Lee,et al. AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis , 2018, Oncology reports.
[5] A. Broeks,et al. Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma , 2018, Nature Medicine.
[6] Stephen Broderick,et al. Neoadjuvant PD‐1 Blockade in Resectable Lung Cancer , 2018, The New England journal of medicine.
[7] Gan‐Lin Zhang,et al. Establishment of a murine breast tumor model by subcutaneous or orthotopic implantation , 2018, Oncology letters.
[8] W. Cui,et al. Function of Axl receptor tyrosine kinase in non-small cell lung cancer. , 2017, Oncology letters.
[9] Ross A Soo,et al. De-novo and acquired resistance to immune checkpoint targeting. , 2017, The Lancet. Oncology.
[10] R. Huang,et al. AXL-Driven EMT State as a Targetable Conduit in Cancer. , 2017, Cancer research.
[11] P. Ma,et al. AXL–GAS6 expression can predict for adverse prognosis in non-small cell lung cancer with brain metastases , 2017, Journal of Cancer Research and Clinical Oncology.
[12] Jing Wang,et al. Integrative Analysis Identifies a Novel AXL–PI3 Kinase–PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer , 2017, Clinical Cancer Research.
[13] Thomas R. Cox,et al. Pre-metastatic niches: organ-specific homes for metastases , 2017, Nature Reviews Cancer.
[14] J. Sosman,et al. Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma , 2017, Cell.
[15] H. Stehr,et al. Reprogramming the immunological microenvironment through radiation and targeting Axl , 2016, Nature Communications.
[16] Jianguang Wang,et al. Expression of Axl and its prognostic significance in human breast cancer , 2016, Oncology letters.
[17] M. Smyth,et al. Abstract B115: Improved efficacy of neoadjuvant compared to adjuvant immunotherapy to eradicate metastatic disease , 2016 .
[18] A. Banerjee,et al. Effector, Memory, and Dysfunctional CD8+ T Cell Fates in the Antitumor Immune Response , 2016, Journal of immunology research.
[19] P. Tamboli,et al. Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma , 2016, Oncogene.
[20] J. van Rheenen,et al. Intravital Insights into Heterogeneity, Metastasis, and Therapy Responses. , 2016, Trends in cancer.
[21] Fan Wang,et al. Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition , 2016, Theranostics.
[22] I. Gill,et al. Axl receptor tyrosine kinase is a potential therapeutic target in renal cell carcinoma , 2015, British Journal of Cancer.
[23] R. Salgia,et al. AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma , 2015, Clinical Cancer Research.
[24] K. Davies,et al. The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer , 2014, Nature Reviews Cancer.
[25] Janfeng Wang,et al. The role of Axl in drug resistance and epithelial-to-mesenchymal transition of non-small cell lung carcinoma. , 2014, International journal of clinical and experimental pathology.
[26] Zhengming Chen,et al. Axl receptor tyrosine kinase expression in breast cancer , 2014, Journal of Clinical Pathology.
[27] Y. Jeng,et al. Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma. , 2014, Carcinogenesis.
[28] J. Herz,et al. An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. , 2014, The Journal of clinical investigation.
[29] Melissa Mallon. Data Curation , 2012 .
[30] K. Tai,et al. Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-κB and Brg-1 , 2008, Oncogene.
[31] P. Elvin,et al. Tumour invasion and metastasis: challenges facing drug discovery. , 2005, Current opinion in pharmacology.
[32] M. Blostein,et al. Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells. , 2004, American journal of physiology. Heart and circulatory physiology.
[33] R. Boot-Handford,et al. Receptor Tyrosine Kinase Axl Modulates the Osteogenic Differentiation of Pericytes , 2003, Circulation research.
[34] M. Hung,et al. Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis , 2002, Oncogene.
[35] R. Reis,et al. Expression of tyrosine kinase receptor AXL is associated with worse outcome of metastatic renal cell carcinomas treated with sunitinib. , 2018, Urologic oncology.
[36] Xin-Yun Huang,et al. Mouse models for tumor metastasis. , 2012, Methods in molecular biology.