MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer

[1]  B. Krušlin,et al.  Prostate Cancer—Focus on Cholesterol , 2021, Cancers.

[2]  O. Sansom,et al.  PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer , 2021, Oncogene.

[3]  M. Loda,et al.  ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer , 2021, Cancer Research.

[4]  T. Jiang,et al.  Role of the Sterol Regulatory Element Binding Protein Pathway in Tumorigenesis , 2020, Frontiers in Oncology.

[5]  Nikos Koundouros,et al.  Reprogramming of fatty acid metabolism in cancer , 2019, British Journal of Cancer.

[6]  Yi Mi Wu,et al.  Genomic correlates of clinical outcome in advanced prostate cancer , 2019, Proceedings of the National Academy of Sciences.

[7]  A. Rust,et al.  Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer , 2016, Proceedings of the National Academy of Sciences.

[8]  A. Jemal,et al.  Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.

[9]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[10]  Paul Theodor Pyl,et al.  HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.

[11]  Peng Lee,et al.  Lipid metabolism in prostate cancer. , 2014, American journal of clinical and experimental urology.

[12]  Cole Trapnell,et al.  TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.

[13]  W. Chow,et al.  Nelfinavir inhibits regulated intramembrane proteolysis of sterol regulatory element binding protein‐1 and activating transcription factor 6 in castration‐resistant prostate cancer , 2012, The FEBS journal.

[14]  Steven L Salzberg,et al.  Fast gapped-read alignment with Bowtie 2 , 2012, Nature Methods.

[15]  O. Sansom,et al.  HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer , 2011, Proceedings of the National Academy of Sciences.

[16]  R. Wilson,et al.  Modernizing Reference Genome Assemblies , 2011, PLoS biology.

[17]  Dennis C. Friedrich,et al.  A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries , 2011, Genome Biology.

[18]  Shota Suto,et al.  ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis , 2010, Proceedings of the National Academy of Sciences.

[19]  Yusuke Nakamura,et al.  Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism. , 2009, Cancer research.

[20]  J. Goldstein,et al.  The LDL receptor. , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[21]  M. Gleave,et al.  Dysregulation of Sterol Response Element-Binding Proteins and Downstream Effectors in Prostate Cancer during Progression to Androgen Independence , 2004, Cancer Research.

[22]  R. B. Rawson Regulated intramembrane proteolysis: from the endoplasmic reticulum to the nucleus. , 2002, Essays in biochemistry.

[23]  X. Chen,et al.  ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. , 2000, Molecular cell.

[24]  X. Hua,et al.  Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment , 1996, Cell.

[25]  X. Hua,et al.  SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis , 1994, Cell.

[26]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[27]  C. Huggins,et al.  Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate , 1941, CA: a cancer journal for clinicians.