A comprehensive overview of studies that assessed article retractions within the biomedical sciences.

This study aims to provide a comprehensive overview of previous research that has investigated retractions within the biomedical fields and assess their methodological quality.We searched three major electronic databases for articles on retractions within the biomedical field: PubMed, Web of Science, and Scopus. In total, 162 articles were included in the analysis. We evaluated their methodological quality using the items of "a measurement tool to assess systematic reviews" (AMSTAR-2) checklist and the Cochrane guidance.The studies had been published in more than 20 biomedical disciplines or fields of investigation, and two-thirds were published after 2017. Concerning methodology, none of the studies fulfilled all the suggested items; five studies did not meet any of the suggested AMSTAR-2 categories or Cochrane guidelines. The most prevalent reported reasons for retraction were fraud and plagiarism (21.0%).In summary, there has been increasing interest in assessing the characteristics and impact of retractions in the biomedical sciences. The studies cited types of misconduct more often than honest errors as a major reason for retraction. The methodological quality of the existing studies in this area appears to be suboptimal. Future investigators should improve upon this, particularly in the quality of the data selection and extraction.