Quantitative photoacoustic tomography

In this paper, several algorithms that allow for quantitative photoacoustic reconstruction of tissue optical, acoustic and physiological properties are described in a finite-element method based framework. These quantitative reconstruction algorithms are compared, and the merits and limitations associated with these methods are discussed. In addition, a multispectral approach is presented for concurrent reconstructions of multiple parameters including deoxyhaemoglobin, oxyhaemoglobin and water concentrations as well as acoustic speed. Simulation and in vivo experiments are used to demonstrate the effectiveness of the reconstruction algorithms presented.

[1]  Zhongping Chen,et al.  Clinical testing of a photoacoustic probe for port wine stain depth determination , 2002, Lasers in surgery and medicine.

[2]  Qiang Wang,et al.  Quantitative photoacoustic tomography: recovery of optical absorption coefficient maps of heterogeneous media , 2007, SPIE BiOS.

[3]  Jan Laufer,et al.  Quantitative spatially resolved measurement of tissue chromophore concentrations using photoacoustic spectroscopy: application to the measurement of blood oxygenation and haemoglobin concentration , 2007, Physics in medicine and biology.

[4]  E. Miller,et al.  Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomography. , 2004, Optics letters.

[5]  M. Schweiger,et al.  Diffuse optical tomography with spectral constraints and wavelength optimization. , 2005, Applied optics.

[6]  Huabei Jiang,et al.  Three-dimensional finite-element-based photoacoustic tomography: reconstruction algorithm and simulations. , 2007, Medical physics.

[7]  Vasilis Ntziachristos,et al.  Quantitative point source photoacoustic inversion formulas for scattering and absorbing media. , 2005, Physical review. E, Statistical, nonlinear, and soft matter physics.

[8]  F. D. de Mul,et al.  Three-dimensional photoacoustic imaging of blood vessels in tissue. , 1998, Optics letters.

[9]  H Jiang,et al.  Quantitative optical image reconstruction of turbid media by use of direct-current measurements. , 2000, Applied optics.

[10]  Huabei Jiang,et al.  Simultaneous reconstruction of acoustic and optical properties of heterogeneous media by quantitative photoacoustic tomography. , 2006, Optics express.

[11]  Simon R Arridge,et al.  Two-dimensional quantitative photoacoustic image reconstruction of absorption distributions in scattering media by use of a simple iterative method. , 2006, Applied optics.

[12]  Lihong V. Wang,et al.  Photoacoustic tomography , 2008, 2008 Conference on Lasers and Electro-Optics and 2008 Conference on Quantum Electronics and Laser Science.

[13]  M. Schweiger,et al.  Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography. , 2003, Optics letters.

[14]  Minghua Xu,et al.  Photoacoustic tomography of biological tissues with high cross-section resolution: reconstruction and experiment. , 2002, Medical physics.

[15]  T. Vo‐Dinh,et al.  Optoacoustic diffraction tomography: analysis of algorithms. , 2003, Journal of the Optical Society of America. A, Optics, image science, and vision.

[16]  Huabei Jiang,et al.  Simultaneous recovery of tissue physiological and acoustic properties and the criteria for wavelength selection in multispectral photoacoustic tomography. , 2009, Optics letters.

[17]  F. M. van den Engh,et al.  Initial results of in vivo non-invasive cancer imaging in the human breast using near-infrared photoacoustics. , 2007, Optics express.

[18]  Qiang Wang,et al.  Tomographic imaging of absolute optical absorption coefficient in turbid media using combined photoacoustic and diffusing light measurements. , 2007, Optics letters.

[19]  Martin Frenz,et al.  Combined ultrasound and optoacoustic system for real-time high-contrast vascular imaging in vivo , 2005, IEEE Transactions on Medical Imaging.

[20]  Yao Sun,et al.  Simultaneous reconstruction of acoustic and optical properties of heterogeneous tissues by quantitative photoacoustic tomography , 2007, SPIE BiOS.

[21]  R A Kruger,et al.  Photoacoustic ultrasound: pulse production and detection of 0.5% Liposyn. , 1994, Medical physics.

[22]  Qiang Wang,et al.  Reconstruction of optical absorption coefficient maps of heterogeneous media by photoacoustic tomography coupled with diffusion equation based regularized Newton method. , 2007, Optics express.

[23]  Zhen Yuan,et al.  Tomographic x-ray-guided three-dimensional diffuse optical tomography of osteoarthritis in the finger joints. , 2008, Journal of biomedical optics.

[24]  R A Kruger,et al.  Thermoacoustic computed tomography--technical considerations. , 1999, Medical physics.

[25]  Da Xing,et al.  Fast photoacoustic imaging system based on 320-element linear transducer array. , 2004, Physics in medicine and biology.

[26]  Alexander A. Oraevsky,et al.  Laser optoacoustic imaging of the breast: detection of cancer angiogenesis , 1999, Photonics West - Biomedical Optics.

[27]  Hua-bei Jiang,et al.  Spatially varying optical and acoustic property reconstruction using finite-element-based photoacoustic tomography. , 2006, Journal of the Optical Society of America. A, Optics, image science, and vision.

[28]  J. Greenleaf,et al.  Clinical Imaging with Transmissive Ultrasonic Computerized Tomography , 1981, IEEE Transactions on Biomedical Engineering.

[29]  James F. Greenleaf,et al.  CLINICAL IMAGING WITH TRANSMISSIVE ULTRASONIC COMPUTERIZED TOMOGRAPHY , 1981 .