A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial.
暂无分享,去创建一个
L. Moldawer | E. Bulger | G. Maislin | J. Sperry | R. Maier | F. Moore | M. Cohen | S. Opal | M. Schreiber | D. Demetriades | P. Talving | S. Henry | R. Kaempfer | A. Shirvan | Bruce Ham | Manjari Joshi | Irit Segalovich
[1] D. Saltzman,et al. Predictors of Mortality and Limb Loss in Necrotizing Soft Tissue Infections , 2013, The American surgeon.
[2] S. Opal,et al. A peptide antagonist of CD28 signaling attenuates toxic shock and necrotizing soft-tissue infection induced by Streptococcus pyogenes. , 2013, The Journal of infectious diseases.
[3] T. Miyakawa,et al. Genomic responses in mouse models poorly mimic human inflammatory diseases , 2013 .
[4] R. Kaempfer,et al. Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock , 2011, PLoS biology.
[5] A. Norrby-Teglund,et al. Getting under the skin: the immunopathogenesis of Streptococcus pyogenes deep tissue infections. , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[6] E. Bulger,et al. Predicting death in necrotizing soft tissue infections: a clinical score. , 2009, Surgical infections.
[7] J. Cuschieri. Necrotizing soft tissue infection. , 2008, Surgical infections.
[8] E. Dellinger,et al. Necrotizing soft-tissue infection: diagnosis and management. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[9] Chin-Ho Wong,et al. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: A tool for distinguishing necrotizing fasciitis from other soft tissue infections* , 2004, Critical care medicine.
[10] S. Schnall,et al. Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality. , 2004, The Journal of bone and joint surgery. American volume.
[11] R. Kaempfer,et al. Broad-spectrum immunity against superantigens is elicited in mice protected from lethal shock by a superantigen antagonist peptide. , 2004, Immunology letters.
[12] T. Dominguez,et al. Scoring for multiple organ dysfunction: Multiple Organ Dysfunction Score, Logistic Organ Dysfunction, or Sequential Organ Failure Assessment. , 2002, Critical care medicine.
[13] R. Kaempfer,et al. Defense against biologic warfare with superantigen toxins. , 2002, The Israel Medical Association journal : IMAJ.
[14] R. Kaempfer,et al. Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock , 2001, Journal of leukocyte biology.
[15] S. Opal,et al. The activity of tissue factor pathway inhibitor in experimental models of superantigen-induced shock and polymicrobial intra-abdominal sepsis , 2001, Critical care medicine.
[16] R. A. Myers,et al. The microbiology of necrotizing soft tissue infections. , 2000, American journal of surgery.
[17] R. Kaempfer,et al. Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation , 2000, Nature Medicine.
[18] R. Kaul,et al. Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group. , 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[19] D. Stevens,et al. Superantigens associated with staphylococcal and streptococcal toxic shock syndrome are potent inducers of tumor necrosis factor-beta synthesis. , 1993, The Journal of infectious diseases.
[20] P. Marrack,et al. The staphylococcal enterotoxins and their relatives. , 1990, Science.
[21] P. Marrack,et al. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells , 1990, The Journal of experimental medicine.
[22] E. Draper,et al. APACHE II: A severity of disease classification system , 1985, Critical care medicine.
[23] W. Knaus,et al. APACHE II: a severity of disease classification system. , 1985 .
[24] P. Marrack,et al. Superantigens: mechanism of T-cell stimulation and role in immune responses. , 1991, Annual review of immunology.