Establishment of an experimental rat model of high altitude cerebral edema by hypobaric hypoxia combined with temperature fluctuation

[1]  Yi Zhang,et al.  Establishment and evaluation of a simulated high-altitude hypoxic brain injury model in SD rats , 2019, Molecular medicine reports.

[2]  Bin Xu,et al.  HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure , 2019, Brain, Behavior, and Immunity.

[3]  Yunhong Li,et al.  Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice , 2019, Respiratory Physiology & Neurobiology.

[4]  Yunhong Li,et al.  Research advances in pathogenesis and prophylactic measures of acute high altitude illness. , 2018, Respiratory medicine.

[5]  Y. Tu,et al.  Exendin-4 inhibits high-altitude cerebral edema by protecting against neurobiological dysfunction , 2018, Neural regeneration research.

[6]  L. Yin,et al.  Ganglioside GM1 protects against high altitude cerebral edema in rats by suppressing the oxidative stress and inflammatory response via the PI3K/AKT‐Nrf2 pathway , 2018, Molecular immunology.

[7]  D. Bailey,et al.  13 reasons why the brain is susceptible to oxidative stress , 2018, Redox biology.

[8]  Shang He,et al.  Mechanism of aquaporin 4 (AQP 4) up‐regulation in rat cerebral edema under hypobaric hypoxia and the preventative effect of puerarin , 2018, Life sciences.

[9]  Megan N. Lilly,et al.  Targeting Na/K-ATPase Signaling: A New Approach to Control Oxidative Stress. , 2018, Current pharmaceutical design.

[10]  Alex J. Smith,et al.  The aquaporin-4 water channel as a potential drug target in neurological disorders , 2017, Expert opinion on therapeutic targets.

[11]  Y. Liu,et al.  Cold stress-induced brain injury regulates TRPV1 channels and the PI3K/AKT signaling pathway , 2017, Brain Research.

[12]  Ruoli Chen,et al.  Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice , 2017, Brain, Behavior, and Immunity.

[13]  Lian-Cheng Zhang,et al.  Diazoxide protects rat vascular endothelial cells against hypoxia and cold-induced damage , 2017, Experimental and therapeutic medicine.

[14]  P. Hackett,et al.  Advances in the Prevention and Treatment of High Altitude Illness. , 2017, Emergency medicine clinics of North America.

[15]  G. Rutter,et al.  The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus. , 2017, Antioxidants & redox signaling.

[16]  I. Galea,et al.  The blood-brain barrier in systemic inflammation , 2017, Brain, Behavior, and Immunity.

[17]  H. Parsons,et al.  Magnetic Resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema , 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[18]  J. Lafuente,et al.  Cold Environment Exacerbates Brain Pathology and Oxidative Stress Following Traumatic Brain Injuries: Potential Therapeutic Effects of Nanowired Antioxidant Compound H-290/51 , 2017, Molecular Neurobiology.

[19]  A. P. Einholm,et al.  Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function. , 2016, Biochimica et biophysica acta.

[20]  S. Mori,et al.  Effects of Cold Stimulation on Mitochondrial Activity and VEGF Expression in vitro , 2016, International Journal of Sports Medicine.

[21]  Xue-qun Chen,et al.  Systemic pro-inflammatory response facilitates the development of cerebral edema during short hypoxia , 2016, Journal of Neuroinflammation.

[22]  S. Saumya,et al.  Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain , 2015, Journal of Neuroinflammation.

[23]  B. Cheng,et al.  Attenuating systemic inflammatory markers in simulated high-altitude exposure by heat shock protein 70-mediated hypobaric hypoxia preconditioning in rats. , 2015, Journal of the Formosan Medical Association = Taiwan yi zhi.

[24]  G. Tattersall,et al.  Body temperature regulation during acclimation to cold and hypoxia in rats. , 2014, Journal of thermal biology.

[25]  Xue-qun Chen,et al.  Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema , 2014, Proceedings of the National Academy of Sciences.

[26]  S. A. Devi,et al.  Intermittent cold-induced hippocampal oxidative stress is associated with changes in the plasma lipid composition and is modifiable by vitamins C and E in old rats , 2014, Neurochemistry International.

[27]  K. Zafren.  Prevention of high altitude illness. , 2014, Travel medicine and infectious disease.

[28]  R. Ransohoff,et al.  Development, maintenance and disruption of the blood-brain barrier , 2013, Nature Medicine.

[29]  Han Luo,et al.  Establishment and evaluation of an experimental animal model of high altitude cerebral edema , 2013, Neuroscience Letters.

[30]  S. Tufik,et al.  Can High Altitude Influence Cytokines and Sleep? , 2013, Mediators of inflammation.

[31]  A. Bansal,et al.  Quercetin as a prophylactic measure against high altitude cerebral edema. , 2012, Free radical biology & medicine.

[32]  S. Dhananjay,et al.  Role of oxidative stress and inflammation in hypoxia-induced cerebral edema: a molecular approach. , 2010, High altitude medicine & biology.

[33]  Alex J. Baneke,et al.  What role does the blood brain barrier play in acute mountain sickness? , 2010, Travel medicine and infectious disease.

[34]  M. Knauth,et al.  Emerging concepts in acute mountain sickness and high-altitude cerebral edema: from the molecular to the morphological , 2009, Cellular and Molecular Life Sciences.

[35]  G. Ilavazhagan,et al.  Neuroprotective effect of cobalt chloride on hypobaric hypoxia-induced oxidative stress , 2008, Neurochemistry International.

[36]  P. K. Banerjee,et al.  Hypobaric hypoxia induces oxidative stress in rat brain , 2006, Neurochemistry International.

[37]  Ş. Yüksel,et al.  Effects of extended cold exposure on antioxidant defense system of rat hypothalamic–pituitary–adrenal axis , 2006 .

[38]  Uwe Christians,et al.  Greater free plasma VEGF and lower soluble VEGF receptor-1 in acute mountain sickness. , 2005, Journal of applied physiology.

[39]  E. Sahin,et al.  Cold-stress-induced modulation of antioxidant defence: role of stressed conditions in tissue injury followed by protein oxidation and lipid peroxidation , 2004, International journal of biometeorology.

[40]  J. West.  The Physiologic Basis of High-Altitude Diseases , 2004, Annals of Internal Medicine.

[41]  R. Kordi,et al.  Acute Mountain Sickness in Iranian Trekkers Around Mount Damavand (5671 m) in Iran , 2003, Wilderness & environmental medicine.

[42]  J. Sznajder,et al.  Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta. , 2003, The Journal of clinical investigation.

[43]  Silvia Fischer,et al.  Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain. , 2002, Brain : a journal of neurology.

[44]  M. Tschöp,et al.  Weight loss at high altitude. , 2001, Advances in experimental medicine and biology.

[45]  M. Tschöp,et al.  High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein. , 2000, Cytokine.

[46]  P. Chan,et al.  Cold injury in mice: a model to study mechanisms of brain edema and neuronal apoptosis , 1999, Progress in Neurobiology.

[47]  J. Severinghaus,et al.  Rat brain VEGF expression in alveolar hypoxia: possible role in high-altitude cerebral edema. , 1998, Journal of applied physiology.

[48]  H. H. Draper,et al.  Malondialdehyde determination as index of lipid peroxidation. , 1990, Methods in enzymology.

[49]  J. Dickinson.  Severe acute mountain sickness. , 1979, Postgraduate medical journal.

[50]  D. H. Will,et al.  Accentuated hypoxemia at high altitude in subjects susceptible to high-altitude pulmonary edema. , 1979, Journal of applied physiology: respiratory, environmental and exercise physiology.