Chemical Constituents of Cordyceps cicadae

One new bifuran derivative (1), together with fourteen known compounds, were isolated from Cordyceps cicadae X. Q. Shing. The known compounds included nine nucleosides, uracil (2), uridine (3), 2′-deoxyuridine (4), 2′-deoxyinosine (5), guanosine (6), 2′-deoxyguanosine (7), thymidine (8), adenosine (9), and 2′-deoxyadenosine (10); three amino acids tryptophan (11), phenylalanine (12), and tyrosine (13); and two dopamine analogues N-acetylnoradrenaline (14) and its dimer, trans–2-(3′,4′-dihydroxyphenyl)-3-acetylamino-7-(N-acetyl-2″-amino-ethylene)-1,4-benzodioxane (15). Their structures were decisively elucidated by spectroscopic analysis, including 1D and 2D NMR techniques.

[1]  Lei Wang,et al.  Cyclodepsipeptides from the ascocarps and insect-body portions of fungus Cordyceps cicadae. , 2014, Fitoterapia.

[2]  Da-yuan Zhu,et al.  Three New 24-Nortriterpenoids from the Roots of Ilex asprella , 2014 .

[3]  Junliang Yang,et al.  Distribution of Nucleosides in Populations of Cordyceps cicadae , 2014, Molecules.

[4]  Kyong-Tai Kim,et al.  Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation , 2008, Archives of pharmacal research.

[5]  Shu-wei Zhang,et al.  Cyclopentenone and Furan Derivative from the Mycelia of Cordyceps cicadae , 2008, The Journal of Antibiotics.

[6]  Shu-wei Zhang,et al.  Five aromatics bearing a 4-O-methylglucose unit from Cordyceps cicadae , 2007 .

[7]  Lie-Chwen Lin,et al.  CYCLODESIPEPTIDE AND DIOXOMORPHOLINE DERIVATIVES ISOLATED FROM THE INSECT- BODY PORTION OF THE FUNGUS CORDYCEPS CICADAE , 2002 .

[8]  T. Okumoto,et al.  Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. , 1994, The Journal of antibiotics.

[9]  Tadashi,et al.  Polysaccharides in Fungi. XXII. : A Water-Soluble Polysaccharide from the Alakaline Extract of the Insect-Body Portion Chan hua (Fungus : Cordyceps cicadae). , 1988 .

[10]  C. Hara,et al.  Structure of a new galactomannan from the ascocarps of Cordyceps cicadae shing , 1982 .

[11]  Jiao Song,et al.  Two novel isoquinoline alkaloids from the seedling of Corydalis decumbens , 2015 .

[12]  Jing Xu,et al.  A new heterocyclic compound from Cyathula officinalis Kuan , 2010 .

[13]  T. Furuya,et al.  N6-(2-hydroxyethyl)adenosine, a biologically active compound from cultured mycelia of Cordyceps and Isaria species , 1983 .