Proteomic approaches to characterize protein modifications: new tools to study the effects of environmental exposures.
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[1] D. Liebler,et al. Peptide sequence motif analysis of tandem MS data with the SALSA algorithm. , 2002, Analytical chemistry.
[2] K. Tew,et al. Glutathione S-transferase P1–1 (GSTP1–1) Inhibits c-Jun N-terminal Kinase (JNK1) Signaling through Interaction with the C Terminus* , 2001, The Journal of Biological Chemistry.
[3] S. Tannenbaum,et al. Site-selective nitration of tyrosine in human serum albumin by peroxynitrite. , 2001, Analytical biochemistry.
[4] K. Kang,et al. Glutathione S-Transferase Mu Modulates the Stress-activated Signals by Suppressing Apoptosis Signal-regulating Kinase 1* , 2001, The Journal of Biological Chemistry.
[5] D. Liebler,et al. SALSA: a pattern recognition algorithm to detect electrophile-adducted peptides by automated evaluation of CID spectra in LC-MS-MS analyses. , 2001, Analytical chemistry.
[6] J. Yates,et al. Large-scale analysis of the yeast proteome by multidimensional protein identification technology , 2001, Nature Biotechnology.
[7] International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome , 2001, Nature.
[8] D. Liebler,et al. Tandem MS analysis of model peptide adducts from reactive metabolites of the hepatotoxin 1,1-dichloroethylene. , 2000, Chemical research in toxicology.
[9] D. Liebler,et al. Characterization of benzoquinone-peptide adducts by electrospray mass spectrometry. , 2000, Chemical research in toxicology.
[10] K. Tew,et al. Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. , 2000, Cancer research.
[11] D Fenyö,et al. Identifying the proteome: software tools. , 2000, Current opinion in biotechnology.
[12] M. Mann,et al. Proteomics to study genes and genomes , 2000, Nature.
[13] Z. Ronai,et al. Amino-terminal-derived JNK Fragment Alters Expression and Activity of c-Jun, ATF2, and p53 and Increases H2O2-induced Cell Death* , 2000, The Journal of Biological Chemistry.
[14] Stephen Naylor,et al. Identification of the protein-drug adduct formed between aldehyde dehydrogenase and S-methyl-N,N-diethylthiocarbamoyl sulfoxide by on-line proteolytic digestion high performance liquid chromatography electrospray ionization mass spectrometry. , 2000, Rapid communications in mass spectrometry : RCM.
[15] A. Shevchenko,et al. MALDI quadrupole time-of-flight mass spectrometry: a powerful tool for proteomic research. , 2000, Analytical chemistry.
[16] R. Aebersold,et al. Identification of Flow-dependent Endothelial Nitric-oxide Synthase Phosphorylation Sites by Mass Spectrometry and Regulation of Phosphorylation and Nitric Oxide Production by the Phosphatidylinositol 3-Kinase Inhibitor LY294002* , 1999, The Journal of Biological Chemistry.
[17] B. van de Water,et al. Distinct endoplasmic reticulum signaling pathways regulate apoptotic and necrotic cell death following iodoacetamide treatment. , 1999, Chemical research in toxicology.
[18] P. Farmer. Studies using specific biomarkers for human exposure assessment to exogenous and endogenous chemical agents. , 1999, Mutation research.
[19] J. Yates,et al. Direct analysis of protein complexes using mass spectrometry , 1999, Nature Biotechnology.
[20] M. Posewitz,et al. Immobilized gallium(III) affinity chromatography of phosphopeptides. , 1999, Analytical chemistry.
[21] R. Kaufman,et al. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. , 1999, Genes & development.
[22] M. Pincus,et al. Regulation of JNK signaling by GSTp , 1999, The EMBO journal.
[23] J. D. Engel,et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. , 1999, Genes & development.
[24] A. Burlingame,et al. Identification of the Hepatic Protein Targets of Reactive Metabolites of Acetaminophen in Vivo in Mice Using Two-dimensional Gel Electrophoresis and Mass Spectrometry* , 1998, The Journal of Biological Chemistry.
[25] Kohei Miyazono,et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1 , 1998, The EMBO journal.
[26] J. A. Hill,et al. Detection and identification of carcinogen-peptide adducts by nanoelectrospray tandem mass spectrometry , 1998, Journal of the American Society for Mass Spectrometry.
[27] Ruedi Aebersold,et al. High throughput protein characterization by automated reverse‐phase chromatography/electrospray tandem mass spectrometry , 1998, Protein science : a publication of the Protein Society.
[28] A L Burlingame,et al. Mechanisms for covalent binding of benoxaprofen glucuronide to human serum albumin. Studies By tandem mass spectrometry. , 1998, Drug metabolism and disposition: the biological fate of chemicals.
[29] J. Yates. Mass spectrometry and the age of the proteome. , 1998, Journal of mass spectrometry : JMS.
[30] R. Hanzlik,et al. Detection of benzoquinone adducts to rat liver protein sulfhydryl groups using specific antibodies. , 1997, Chemical research in toxicology.
[31] Hong Liu,et al. Endoplasmic Reticulum Chaperones GRP78 and Calreticulin Prevent Oxidative Stress, Ca2+ Disturbances, and Cell Death in Renal Epithelial Cells* , 1997, The Journal of Biological Chemistry.
[32] Steven D. Cohen,et al. Selective protein covalent binding and target organ toxicity. , 1997, Toxicology and applied pharmacology.
[33] N. Pumford,et al. Covalent binding of xenobiotics to specific proteins in the liver. , 1997, Drug metabolism reviews.
[34] S. Gaskell,et al. First Direct Evidence for Lipid/Protein Conjugation in Oxidized Human Low Density Lipoprotein* , 1996, The Journal of Biological Chemistry.
[35] C. Leslie,et al. Identification of Phosphorylation Sites of Human 85-kDa Cytosolic Phospholipase A Expressed in Insect Cells and Present in Human Monocytes (*) , 1996, The Journal of Biological Chemistry.
[36] B. Martin,et al. Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac. , 1995, Chemical research in toxicology.
[37] A. Burlingame,et al. Synthesis and mass-spectrometric characterization of human serum albumins modified by covalent binding of two non-steroidal anti-inflammatory drugs: tolmetin and zomepirac. , 1995, The Biochemical journal.
[38] D. J. Reed,et al. Alkylation of Escherichia coli thioredoxin by S-(2-chloroethyl)glutathione and identification of the adduct on the active site cysteine-32 by mass spectrometry. , 1995, Chemical research in toxicology.
[39] J. Yates,et al. Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database. , 1995, Analytical chemistry.
[40] D. J. Reed,et al. Alkylation of oxytocin by S-(2-chloroethyl)glutathione and characterization of adducts by tandem mass spectrometry and Edman degradation. , 1995, Chemical research in toxicology.
[41] Steven D. Cohen,et al. A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3'-hydroxyacetanilide. , 1995, Chemical research in toxicology.
[42] A. Burlingame,et al. Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry. , 1995, Drug metabolism and disposition: the biological fate of chemicals.
[43] Hong Liu,et al. Signalling the molecular stress response to nephrotoxic and mutagenic cysteine conjugates: Differential roles for protein synthesis and calcium in the induction of c‐fos and c‐myc mRNA in LLC‐PK1 cells , 1994, Journal of cellular physiology.
[44] S. Tannenbaum,et al. Protein adducts as biomarkers of human carcinogen exposure. , 1994, Drug metabolism reviews.
[45] J. Stevens,et al. Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity. , 1993, The Journal of biological chemistry.
[46] A. Burlingame,et al. Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[47] J. Hinson,et al. Role of covalent and noncovalent interactions in cell toxicity: effects on proteins. , 1992, Annual review of pharmacology and toxicology.
[48] J. Holme,et al. Comparative cytotoxic effects of acetaminophen (N-acetyl-p-aminophenol), a non-hepatotoxic regioisomer acetyl-m-aminophenol and their postulated reactive hydroquinone and quinone metabolites in monolayer cultures of mouse hepatocytes. , 1991, Biochemical pharmacology.
[49] T. Baillie,et al. Carbamoylation of peptides and proteins in vitro by S-(N-methylcarbamoyl)glutathione and S-(N-methylcarbamoyl)cysteine, two electrophilic S-linked conjugates of methyl isocyanate. , 1991, Chemical research in toxicology.
[50] T. Myers,et al. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse. , 1990, Drug metabolism and disposition: the biological fate of chemicals.
[51] S. Tannenbaum,et al. Protein adducts in the molecular dosimetry of chemical carcinogens. , 1990, Carcinogenesis.
[52] P. Pearson,et al. Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals. , 1990, Annual review of pharmacology and toxicology.
[53] A. Burlingame,et al. Characterization of structural xenobiotic modifications in proteins by high sensitivity tandem mass spectrometry. Human hemoglobin treated in vitro with styrene 7,8-oxide. , 1989, The Journal of biological chemistry.
[54] D. Liebler,et al. S-(2-chloroacetyl)glutathione, a reactive glutathione thiol ester and a putative metabolite of 1,1-dichloroethylene. , 1988, Biochemistry.
[55] D. Mccormick. Sequence the Human Genome , 1986, Bio/Technology.
[56] P. Moldéus,et al. The role of metabolic activation in drug toxicity. , 1985, Chemioterapia : international journal of the Mediterranean Society of Chemotherapy.
[57] V. Ferrans,et al. Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes. , 1985, The Journal of pharmacology and experimental therapeutics.
[58] D. Liebler,et al. Enzymatic activation of chemicals to toxic metabolites. , 1985, Critical reviews in toxicology.
[59] T. Monks,et al. Multiple reactive metabolites derived from bromobenzene. , 1984, Drug Metabolism And Disposition.
[60] E C Miller,et al. Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules , 1981, Cancer.
[61] Brian W. Kernighan,et al. Software tools , 1976, SOEN.
[62] S. Thorgeirsson,et al. Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. , 1974, Pharmacology.
[63] S. Thorgeirsson,et al. Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. , 1974, Pharmacology.
[64] D. Jollow,et al. Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. , 1974, Pharmacology.
[65] B B Brodie,et al. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. , 1973, The Journal of pharmacology and experimental therapeutics.
[66] B. Brodie,et al. ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. III. CYTOCHROME P-450-MEDIATED COVALENT BINDING IN VITRO , 1973 .