Constitutive expression of multidrug resistance in human colorectal tumours and cell lines.

[1]  C. Fisher.  Heterogeneity of Cancer Cells , 1994 .

[2]  F. Baas,et al.  Monoclonal antibody to an external epitope of the human mdr1 P-glycoprotein. , 1993, Cancer research.

[3]  H. Westerhoff,et al.  Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells. , 1992, European journal of biochemistry.

[4]  V. Ling,et al.  P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. , 1991, The New England journal of medicine.

[5]  D. Scudiero,et al.  Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. , 1991, Journal of the National Cancer Institute.

[6]  J. Kuszak,et al.  Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. , 1991, Cancer research.

[7]  G. Margison,et al.  Assessment of P-glycoprotein, glutathione-based detoxifying enzymes and O6-alkylguanine-DNA alkyltransferase as potential indicators of constitutive drug resistance in human colorectal tumors. , 1991, Cancer research.

[8]  J. Lankelma,et al.  P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport. , 1991, Biochemical pharmacology.

[9]  T. Tsuruo,et al.  Expression of the MDR1 gene in human gastric and colorectal carcinomas. , 1990, Journal of the National Cancer Institute.

[10]  M. Melamed,et al.  Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. , 1990, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[11]  P. Brousset,et al.  Immunohistochemical detection of multidrug resistance associated P-glycoprotein in tumour and stromal cells of human cancers. , 1990, British Journal of Cancer.

[12]  D. Scudiero,et al.  New colorimetric cytotoxicity assay for anticancer-drug screening. , 1990, Journal of the National Cancer Institute.

[13]  B. Kramer,et al.  Chemosensitivity patterns and expression of human multidrug resistance-associated MDR1 gene by human gastric and colorectal carcinoma cell lines. , 1990, Journal of the National Cancer Institute.

[14]  I. Pastan,et al.  MDR1 gene expression in lung cancer. , 1989, Journal of the National Cancer Institute.

[15]  P. Meltzer,et al.  Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy. , 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  R. Koff.  Multidrug resistance in cancer cells: Biochemical mechanisms , 1989 .

[17]  A. Mercurio,et al.  Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell lines. , 1989, Cancer research.

[18]  I. Pastan,et al.  Expression of Multidrug Resistance Gene in Human Cancers , 1989 .

[19]  Robert,et al.  Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus. , 1989, The Journal of biological chemistry.

[20]  I. Pastan,et al.  Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells. , 1988, Biochemistry.

[21]  R. Kramer,et al.  Role of the glutathione redox cycle in acquired and de novo multidrug resistance. , 1988, Science.

[22]  D. Haller.  Chemotherapy in gastrointestinal malignancies. , 1988, Seminars in oncology.

[23]  V. Ling,et al.  Electrophoretic analysis of P-glycoproteins produced by mouse J774.2 and Chinese hamster ovary multidrug-resistant cells. , 1988, Journal of the National Cancer Institute.

[24]  I. Pastan,et al.  Intrinsic drug resistance in human kidney cancer is associated with expression of a human multidrug-resistance gene. , 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  M C Willingham,et al.  Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[26]  V. Ling,et al.  P-glycoprotein in human sarcoma: evidence for multidrug resistance. , 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[27]  J. Isbister,et al.  DETECTION OF A MULTIDRUG RESISTANT PHENOTYPE IN ACUTE NON-LYMPHOBLASTIC LEUKAEMIA , 1987, The Lancet.

[28]  Michael M. Gottesman,et al.  Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells , 1986, Cell.

[29]  I. Pastan,et al.  Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells. , 1986, The Journal of biological chemistry.

[30]  D. Dexter,et al.  Heterogeneity of cancer cells from a single human colon carcinoma. , 1981, The American journal of medicine.

[31]  W. Rutter,et al.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. , 1979, Biochemistry.

[32]  D. Dexter,et al.  N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells. , 1979, Cancer research.

[33]  J. Till,et al.  Pleiotropic phenotype of colchicine‐resistant CHO cells: Cross‐resistance and collateral sensitivity , 1976, Journal of cellular physiology.

[34]  J. L. Biedler,et al.  Cellular resistance to daunomycin in Chinese hamster cells in vitro. , 1971, Cancer research.

[35]  I. Pastan,et al.  Expression of the multidrug resistance, MDR1, gene in neuroblastomas. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[36]  M. Melamed,et al.  Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[37]  M. O'brien,et al.  Isolation and characterization of an undifferentiated human colon carcinoma cell line (MIP-101). , 1987, Cancer investigation.

[38]  I. Pastan,et al.  Expression of a multidrug-resistance gene in human tumors and tissues. , 1987, Proceedings of the National Academy of Sciences of the United States of America.