Bioindustrial and biopharmaceutical products from plants

Plant production of biopharmaceuticals and bioindustrial proteins is a potentially viable industry with tremendous upside potential. Plants allow large amounts of biomass and can be easily and inexpensively produced, with seed based systems being the most economical. Significant technologies, including promoters with tissue-specific activity, and sub-cellular targeting sites that offer protein stability, have been successfully developed to address protein accumulation issues. Crop choices for production, whether for domestic or wild species, are based on many criteria including type of product, cost of production, and safety of the product. Production steps are numerous—from growing and harvesting the crop to transportation, storage, processing, extraction and in some cases protein purification. Examples of products and crop choices will be presented. Legal and regulatory issues also will enter into the decisionmaking process. The industry players must work together to solve a number of problems that are currently at issue, such as regulatory requirements and public acceptance. However, with attention to these details and good stewardship, the success of the industry is possible. Media Summary Plant production of biopharmaceuticals and bioindustrial proteins is a potentially viable industry with tremendous potential. Plants allow large amounts of biomass and can be easily and inexpensively produced.

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