Countermanding saccades with auditory stop signals: testing the race model

In a stop signal paradigm to investigate the control of human saccades subjects were instructed to make a saccade to a visual target appearing suddenly l5 degrees to the left or to the right of the fixation point. In 25% of the trials an auditory stop signal was presented after a variable delay that required the subject to inhibit the saccade. The stop signal was presented randomly at the target position, at the opposite side, or at fixation. Using different estimation techniques the average time needed to inhibit a saccade (stop signal processing time, or SSPT) was estimated on the basis of the race model. The SSPT estimates ranging from 50 to 100 ms (depending on subject) are shorter than those from previous studies with visual stop signals. Position of the auditory stop signal did not show an effect on countermanding effectiveness. We found saccadic response times consistent with the race model predictions for two subjects, while a third subject showed small but consistent violations. Moreover, all subjects showed a tendency towards hypometric saccades for responses that could not be inhibited. These findings are discussed with respect to recent neurophysiological results.

[1]  J. Schall,et al.  Neural Control of Voluntary Movement Initiation , 1996, Science.

[2]  J. Schall,et al.  Role of frontal eye fields in countermanding saccades: visual, movement, and fixation activity. , 1998, Journal of neurophysiology.

[3]  J. Schall.  Neuronal activity related to visually guided saccades in the frontal eye fields of rhesus monkeys: comparison with supplementary eye fields. , 1991, Journal of neurophysiology.

[4]  C. Eriksen,et al.  Use of a delayed signal to stop a visual reaction-time response. , 1966 .

[5]  B. Bergum,et al.  Attention and performance IX , 1982 .

[6]  D. F. Fisher,et al.  Eye movements : cognition and visual perception , 1982 .

[7]  D. Munoz,et al.  Control of saccade initiation in a countermanding task using visual and auditory stop signals , 2000, Experimental Brain Research.

[8]  M. Wallace,et al.  Converging influences from visual, auditory, and somatosensory cortices onto output neurons of the superior colliculus. , 1993, Journal of neurophysiology.

[9]  G. S. Russo,et al.  Frontal eye field activity preceding aurally guided saccades. , 1994, Journal of neurophysiology.

[10]  R. Wurtz,et al.  Composition and topographic organization of signals sent from the frontal eye field to the superior colliculus. , 2000, Journal of neurophysiology.

[11]  D. Meyer,et al.  Attention and Performance XIV , 1973 .

[12]  G. Logan,et al.  In search of the point of no return: the control of response processes. , 1990, Journal of experimental psychology. Human perception and performance.

[13]  R. Klein,et al.  Saccadic Performance as a Function of the Presence and Disappearance of Auditory and Visual Fixation Stimuli , 1999, Journal of Cognitive Neuroscience.

[14]  C. Spence,et al.  On measuring selective attention to an expected sensory modality , 1997, Perception & psychophysics.

[15]  David E. Irwin,et al.  Don’t look! don’t touch! inhibitory control of eye and hand movements , 2000, Psychonomic bulletin & review.

[16]  R. H. S. Carpenter,et al.  Neural computation of log likelihood in control of saccadic eye movements , 1995, Nature.

[17]  Nick Fogt,et al.  The Neurology of Eye Movements, 3rd ed. , 2000 .

[18]  H Colonius,et al.  A two-stage model for visual-auditory interaction in saccadic latencies , 2001, Perception & psychophysics.

[19]  J. Schall,et al.  Countermanding saccades in macaque , 1995, Visual Neuroscience.

[20]  G. Band.  Preparation, adjustment and inhibition of responses , 1997 .

[21]  H N Zelaznik,et al.  The modification of an already-programmed response: a new interpretation of Henry and Harrison (1961). , 1991, Journal of motor behavior.

[22]  M. Alex Meredith,et al.  The frontal eye fields target multisensory neurons in cat superior colliculus , 1999, Experimental Brain Research.

[23]  J. Schall,et al.  Neural selection and control of visually guided eye movements. , 1999, Annual review of neuroscience.

[24]  T. Carr,et al.  Inhibitory Processes in Attention, Memory and Language , 1994 .

[25]  M. Frens,et al.  Spatial and temporal factors determine auditory-visual interactions in human saccadic eye movements , 1995, Perception & psychophysics.

[26]  G. Logan.  On the ability to inhibit thought and action , 1984 .

[27]  R. Carpenter,et al.  Saccadic countermanding: a comparison of central and peripheral stop signals , 2001, Vision Research.

[28]  R. Rafal,et al.  The neurology of inhibition: Integrating controlled and automatic processes. , 1994 .

[29]  A. Opstal,et al.  Visual-auditory interactions modulate saccade-related activity in monkey superior colliculus , 1998, Brain Research Bulletin.

[30]  K. Kudo,et al.  Functional modification of agonist-antagonist electromyographic activity for rapid movement inhibition , 1998, Experimental Brain Research.

[31]  R. Carpenter,et al.  Countermanding saccades in humans , 1999, Vision Research.

[32]  D. Meyer,et al.  The point of no return in choice reaction time: controlled and ballistic stages of response preparation. , 1986, Journal of experimental psychology. Human perception and performance.

[33]  Hans Colonius,et al.  A Note on the Stop-Signal Paradigm, or How to Observe the Unobservable , 1990 .