A Polar Map Based Approach Using Retinal Fundus Images for Glaucoma Detection

Cup-to-disc ratio is commonly used as an important parameter for glaucoma screening, involving segmentation of the optic cup on fundus images. We propose a novel polar map representation of the optic disc, using a combination of supervised and unsupervised cup segmentation techniques, for detection of glaucoma. Instead of performing hard thresholding on the segmentation output to extract the cup, we consider the cup confidence scores inside the disc to construct a polar map, and extract sector-wise features for learning a glaucoma risk probability (GRP) for the image. We compare the performance of GRP vis-a-vis the cup-to-disc ratio (CDR). On an evaluation dataset of 100 images from the publicly available RIM-ONE database, our method achieves 82% sensitivity at 84% specificity, and 96% sensitivity at 60% specificity (AUC of 0.8964). Experiments indicate that the polar map based method can provide a more discriminatory glaucoma risk probability score compared to CDR.

[1]  Francisco Fumero,et al.  RIM-ONE: An open retinal image database for optic nerve evaluation , 2011, 2011 24th International Symposium on Computer-Based Medical Systems (CBMS).

[2]  James C. Gee,et al.  Optic Disc and Cup Segmentation from Color Fundus Photograph Using Graph Cut with Priors , 2013, MICCAI.

[3]  Stephen Lin,et al.  Efficient Reconstruction-Based Optic Cup Localization for Glaucoma Screening , 2013, MICCAI.

[4]  Khan M. Iftekharuddin,et al.  Novel Fractal Feature-Based Multiclass Glaucoma Detection and Progression Prediction , 2013, IEEE Journal of Biomedical and Health Informatics.

[5]  Juan Xu,et al.  3D optical coherence tomography super pixel with machine classifier analysis for glaucoma detection , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  Dacheng Tao,et al.  Sparse Dissimilarity-Constrained Coding for Glaucoma Screening , 2015, IEEE Transactions on Biomedical Engineering.

[7]  Thomas Walter,et al.  Segmentation of Color Fundus Images of the Human Retina: Detection of the Optic Disc and the Vascular Tree Using Morphological Techniques , 2001, ISMDA.

[8]  Baihua Li,et al.  Automatic extraction of retinal features from colour retinal images for glaucoma diagnosis: A review , 2013, Comput. Medical Imaging Graph..

[9]  Stephen Lin,et al.  Optic Cup Segmentation for Glaucoma Detection Using Low-Rank Superpixel Representation , 2014, MICCAI.

[10]  Jui-Kai Wang,et al.  Multimodal Segmentation of Optic Disc and Cup From SD-OCT and Color Fundus Photographs Using a Machine-Learning Graph-Based Approach , 2015, IEEE Transactions on Medical Imaging.

[11]  Joel E.W. Koh,et al.  Glaucoma Classification Using Brownian Motion and Discrete Wavelet Transform , 2014 .

[12]  Kevin Noronha,et al.  Decision support system for the glaucoma using Gabor transformation , 2015, Biomed. Signal Process. Control..

[13]  Tien Yin Wong,et al.  Superpixel Classification Based Optic Disc and Optic Cup Segmentation for Glaucoma Screening , 2013, IEEE Transactions on Medical Imaging.

[14]  U. Rajendra Acharya,et al.  Automated Diagnosis of Glaucoma Using Digital Fundus Images , 2009, Journal of Medical Systems.

[15]  Robert P. W. Duin,et al.  The Dissimilarity Representation for Pattern Recognition - Foundations and Applications , 2005, Series in Machine Perception and Artificial Intelligence.