Efficiency of the left ventricle assist device Hemopump in cardiac fibrillation.

We have examined in sheep the efficiency of the Hemopump during ventricular fibrillation. Circulatory arrest was induced by electrical stimulation and maintained for 30 min. Haemodynamic measurements were recorded continuously and blood samples were taken before, during and after fibrillation to determine total body and myocardial metabolic activity. All hearts were defibrillated successfully after 30 min of fibrillation. During fibrillation, the Hemopump sustained a mean arterial pressure of about 60 mm Hg with a blood flow rate of about 2.3 litre min-1. These perfusion conditions were sufficient for maintenance of aerobic myocardial metabolism, but with a borderline circulatory supply to the total organism.

[1]  G. Hellige,et al.  Myocardial support and protection during regional myocardial ischemia using the Hemopump assist device. , 1991, The thoracic and cardiovascular surgeon.

[2]  E. Topol,et al.  Percutaneous support devices for high risk or complicated coronary angioplasty. , 1991, Journal of the American College of Cardiology.

[3]  J. Dubois-Randé,et al.  Prophylactic intraventricular pumping in high-risk coronary angioplasty , 1990, The Lancet.

[4]  G. Maccioli,et al.  The intra-aortic balloon pump: a review. , 1988, Journal of cardiothoracic anesthesia.

[5]  G. Hellige,et al.  Experimental validation of methods for the measurement of coronary sinus blood flow in man , 1979, Basic Research in Cardiology.

[6]  G. Hellige,et al.  Protective effects of the Hemopump left ventricular assist device in experimental cardiogenic shock. , 1992, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[7]  G. Hellige,et al.  Transfemoral placement of the left ventricular assist device "Hemopump" during mechanical resuscitation. , 1990, The thoracic and cardiovascular surgeon.

[8]  G. Buckberg,et al.  Studies of the effects of hypothermia on regional myocardial blood flow and metabolism during cardiopulmonary bypass. I. The adequately perfused beating, fibrillating, and arrested heart. , 1977 .

[9]  J R Neely,et al.  Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. , 1974, Annual review of physiology.

[10]  G. Friesinger,et al.  CORONARY SINUS DRAINAGE AND MEASUREMENT OF LEFT CORONARY ARTERY FLOW IN THE DOG. , 1964, American Journal of Physiology.