Videodensitometry of osteons in females with femoral neck fractures

SummaryThe medial femoral cortices of 10 females with femoral neck fractures and 10 age-matched female autopsy cases were studied using computer-assisted videodensitometry. Radiographic mineral density was determined using the calibration method described by Martin et al. [20]. Measurements were made of porosity, osteon and haversian canal dimensions, and of interstitial and osteon mineral density across the cortical wall of the orthopedic calcar region. There were no differences between the fracture and nonfracture groups in the overall mean mineral density of the bone averaged over the microstructure, excluding pore space, or in the interstitial bone mineral density. The porosity in the fracture group was greater than in the autopsy group, especially in the periosteal region, where the porosity was 2.4 times greater and where there were also 27% fewer osteons per unit area than in the autopsy group (P<0.05). Mean osteon mineral density was 2.5% higher in the fracture group (P<0.05) compared with the autopsy group in the endosteal region, and 4% higher in the periosteal region. Osteon and haversian canal areas were also larger in the fracture group, especially in the middle region of the cortical wall (17% and 23%, respectively, P<0.05).

[1]  F. Kaplan,et al.  Osteon morphometry in females with femoral neck fractures. , 1992, Clinical orthopaedics and related research.

[2]  N. Dalén,et al.  Bone mineral content and mechanical strength of the femoral neck. , 1976, Acta orthopaedica Scandinavica.

[3]  W C Hayes,et al.  The use of quantitative computed tomography to estimate risk of fracture of the hip from falls. , 1990, The Journal of bone and joint surgery. American volume.

[4]  G U Rao,et al.  Predicting femoral neck strength from bone mineral data. A structural approach. , 1990, Investigative radiology.

[5]  Christopher B. Ruff,et al.  Sex differences in geometry of the femoral neck with aging: A structural analysis of bone mineral data , 2004, Calcified Tissue International.

[6]  S. Furner,et al.  Musculoskeletal Conditions in the United States , 1992 .

[7]  S. K. Chatterji,et al.  Age-related changes in the density and tensile strength of human femoral cortical bone , 1979, Calcified Tissue International.

[8]  E. Simmons,et al.  Age‐related changes in the human femoral cortex , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[9]  D. Burr,et al.  Stiffness of compact bone: effects of porosity and density. , 1988, Journal of biomechanics.

[10]  L. Klenerman,et al.  Rates of spinal bone loss after menopause are predictable TN normal british women , 1992 .

[11]  P. Kälebo,et al.  Bone Mass Determination from Microradiographs by Computer-Assisted Videodensitometry , 1988, Acta radiologica.

[12]  J W SMITH,et al.  Factors affecting the elasticity of bone. , 1959, Journal of anatomy.

[13]  F. Albright,et al.  The Parathyriod Glands and Metabolic Bone Disease. , 1948 .

[14]  B. Vernon‐roberts,et al.  Comparative study of iliac crest and proximal femur histomorphometry in normal patients. , 1989, Journal of clinical pathology.

[15]  I. Hammel,et al.  Osteopenia, hematopoiesis, and bone remodelling in iliac crest and femoral biopsies: a prospective study of 102 cases of femoral neck fractures. , 1991, Bone.

[16]  G. Vose Quantitative microradiography of osteoporotic compact bone. , 1962, Clinical orthopaedics.

[17]  E. Korostoff,et al.  Haversian osteons: size, distribution, internal structure, and orientation. , 1974, Journal of biomedical materials research.

[18]  Vose Gp Quantitative microradiography of osteoporotic compact bone. , 1962 .

[19]  W C Hutton,et al.  The mechanical properties of bone in osteoporosis. , 1981, The Journal of bone and joint surgery. British volume.

[20]  T. Brown,et al.  Mechanical property distributions in the cancellous bone of the human proximal femur. , 1980, Acta orthopaedica Scandinavica.

[21]  F. Albright,et al.  THE PARATHYROID GLANDS AND METABOLIC BONE DISEASE , 1950, The Ulster Medical Journal.

[22]  Roberta Carroll,et al.  Cortical bone senescence and mineral bone density of the humerus , 1983, Calcified Tissue International.

[23]  L. Wilkins Voluntary Medical Care Insurance in the United States , 1949 .

[24]  W. Hayes,et al.  Sex differences in age‐related remodeling of the femur and tibia , 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[25]  E. Kerley,et al.  The microscopic determination of age in human bone. , 1965, American journal of physical anthropology.

[26]  W. Hayes,et al.  Fracture prediction for the proximal femur using finite element models: Part I--Linear analysis. , 1991, Journal of biomechanical engineering.