Dextromethorphan Attenuated Inflammation and Combined Opioid Use in Humans Undergoing Methadone Maintenance Treatment

[1]  Mao-tsun Lin,et al.  Attenuating heat-induced acute lung inflammation and injury by dextromethorphan in rats. , 2012, American journal of respiratory cell and molecular biology.

[2]  P. Chen,et al.  Erratum to: Inflammation in Patients with Schizophrenia: The Therapeutic Benefits of Risperidone Plus Add-On Dextromethorphan , 2012, Journal of Neuroimmune Pharmacology.

[3]  R. Lu,et al.  Low-Dose Memantine Attenuated Morphine Addictive Behavior Through its Anti-Inflammation and Neurotrophic Effects in Rats , 2011, Journal of Neuroimmune Pharmacology.

[4]  R. Lu,et al.  Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats. , 2011, Drug and alcohol dependence.

[5]  B. Jarrott,et al.  Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats , 2011, Brain Research Bulletin.

[6]  Qiang Li,et al.  White matter impairment in heroin addicts undergoing methadone maintenance treatment and prolonged abstinence: A preliminary DTI study , 2011, Neuroscience Letters.

[7]  Ming-Han Li,et al.  Dextromethorphan Efficiently Increases Bactericidal Activity, Attenuates Inflammatory Responses, and Prevents Group A Streptococcal Sepsis , 2011, Antimicrobial Agents and Chemotherapy.

[8]  T. Cunha-Oliveira,et al.  Neurotoxicity of heroin-cocaine combinations in rat cortical neurons. , 2010, Toxicology.

[9]  J. O'Callaghan,et al.  Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management. , 2010, Pain medicine.

[10]  I. Galynker,et al.  Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: performance and neuroimaging results. , 2009, Drug and alcohol dependence.

[11]  K. Pennypacker,et al.  Sigma receptors suppress multiple aspects of microglial activation , 2009, Glia.

[12]  N. Lamash,et al.  Histo- and immunocytochemical detection of inducible NOS and TNF-α in the locus coeruleus of human opiate addicts , 2009, Journal of Chemical Neuroanatomy.

[13]  W. Tsai,et al.  Treatment with dextromethorphan improves endothelial function, inflammation and oxidative stress in male heavy smokers , 2008, Journal of thrombosis and haemostasis : JTH.

[14]  R. LaLumiere,et al.  Glutamate Release in the Nucleus Accumbens Core Is Necessary for Heroin Seeking , 2008, The Journal of Neuroscience.

[15]  Peng Yu,et al.  PRECLINICAL STUDY: Chronic morphine‐induced neuronal morphological changes in the ventral tegmental area in rats are reversed by electroacupuncture treatment , 2008, Addiction biology.

[16]  Li-yan Zhao,et al.  PET imaging of dopamine transporter and drug craving during methadone maintenance treatment and after prolonged abstinence in heroin users. , 2008, European journal of pharmacology.

[17]  Chih-Shung Wong,et al.  Post‐treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats , 2007, Synapse.

[18]  Seung Woo Shin,et al.  Dextromethorphan attenuates trimethyltin-induced neurotoxicity via σ1 receptor activation in rats , 2007, Neurochemistry International.

[19]  F. Crews,et al.  Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration , 2007, Glia.

[20]  E. Shin,et al.  3‐Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP‐elicited damage both in vivo and in vitro , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[21]  S. Rivest,et al.  Do pathogen exposure and innate immunity cause brain diseases? , 2005, Neurological research.

[22]  Tongguang Wang,et al.  Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[23]  Bin Liu,et al.  3‐Hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS‐induced neurotoxicity , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[24]  Shiou-Lan Chen,et al.  Dextromethorphan differentially affects opioid antinociception in rats , 2005, British journal of pharmacology.

[25]  Bin Liu,et al.  Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  H. Ko,et al.  Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. , 2004, Alcoholism, clinical and experimental research.

[27]  J. Deleo,et al.  Attenuation of Morphine Tolerance, Withdrawal-Induced Hyperalgesia, and Associated Spinal Inflammatory Immune Responses by Propentofylline in Rats , 2004, Neuropsychopharmacology.

[28]  E. Huang,et al.  Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens , 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

[29]  B. Liu,et al.  Dextromethorphan Protects Dopaminergic Neurons against Inflammation-Mediated Degeneration through Inhibition of Microglial Activation , 2003, Journal of Pharmacology and Experimental Therapeutics.

[30]  J. Deleo,et al.  The Role of Spinal Neuroimmune Activation in Morphine Tolerance/Hyperalgesia in Neuropathic and Sham-Operated Rats , 2002, The Journal of Neuroscience.

[31]  R. Ehrman,et al.  A randomized, double-blind, placebo-controlled safety study of high-dose dextromethorphan in methadone-maintained male inpatients. , 2002, Drug and alcohol dependence.

[32]  M. Stitzer,et al.  Cognitive impairment in methadone maintenance patients. , 2002, Drug and alcohol dependence.

[33]  R. Houghtling,et al.  Rapid elevation of plasma interleukin-6 by morphine is dependent on autonomic stimulation of adrenal gland. , 2002, The Journal of pharmacology and experimental therapeutics.

[34]  M. Muc-Wierzgoń,et al.  Central single and chronic administration of morphine stimulates corticosterone and interleukin (IL)-6 in adjuvant-induced arthritis. , 2000, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[35]  M. Barrot,et al.  Opiates inhibit neurogenesis in the adult rat hippocampus. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[36]  P. Singhal,et al.  Morphine stimulates mesangial cell TNF-alpha and nitrite production. , 2000, Inflammation.

[37]  T. Robinson,et al.  Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats , 1999, Synapse.

[38]  T. Molitor,et al.  The opioid–cytokine connection , 1998, Journal of Neuroimmunology.

[39]  P. Popik,et al.  Opiate withdrawal with dextromethorphan. , 1997, The American journal of psychiatry.

[40]  G. Koob,et al.  The neurobiology of drug addiction. , 1997, The Journal of neuropsychiatry and clinical neurosciences.

[41]  H. W. Harris,et al.  Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[42]  C. Perego,et al.  Central opiate modulation of peripheral IL‐6 in rats , 1996, Neuroreport.

[43]  Robert C. Thompson,et al.  Primary astroglial cultures derived from several rat brain regions differentially express μ, δ and κ opioid receptor mRNA , 1995 .

[44]  H. Akil,et al.  Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA. , 1995, Brain research. Molecular brain research.

[45]  J. Mclarnon,et al.  Interactions of dextromethorphan with theN-methyl-d-aspartate receptor-channel complex: single channel recordings , 1994, Brain Research.

[46]  H. Balfour,et al.  Morphine amplifies HIV-1 expression in chronically infected promonocytes cocultured with human brain cells , 1994, Journal of Neuroimmunology.

[47]  P. Pflimlin,et al.  Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons. , 1993, European journal of pharmacology.

[48]  A. Springer,et al.  Drug Addiction and AIDS , 1991, Springer Vienna.

[49]  H. Koyuncuoǧlu The Treatment with Dextromethorphan of Heroin Addicts , 1991 .

[50]  S. Duckles,et al.  Multiple sites of action of (+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine ((+)-3PPP) in blood vessels. , 1990, European journal of pharmacology.

[51]  W. Bowen,et al.  Evidence for a multi-site model of the rat brain σ receptor , 1989 .

[52]  E. D. De Souza,et al.  Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary. , 1989, Endocrinology.

[53]  W. Bowen,et al.  Evidence for a multi-site model of the rat brain sigma receptor. , 1989, European journal of pharmacology.

[54]  E. D. De Souza,et al.  Initial identification and characterization of sigma receptors on human peripheral blood leukocytes. , 1988, The Journal of pharmacology and experimental therapeutics.

[55]  T. Su Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain. , 1982, The Journal of pharmacology and experimental therapeutics.

[56]  C. Carter Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats , 1982, Neuropharmacology.

[57]  J. Thompson,et al.  The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. , 1976, The Journal of pharmacology and experimental therapeutics.