Sensor Layer of a Multiparameter Single-Point Integrated System

Microfabrication and circuit integration provide sensors with reduced size, improved performance, increased reliability, and lower cost. These microsensors can measure a variety of properties and behaviors, and are typically constructed on a range of substrate materials in combination with signal conditioning, information processing, and data-communication electronics. The challenge remains to integrate multiple sensors, each measuring different parameters with separate supporting electronics, into a single. high-density microsystem. We describe a multiple parameter medical sensor that is suitable for mounting on an active moving patient where mechanical flexibility, tight adhesion, lightweight, small size, and biocompatibility of an easily applied flat stick-on assembly at a single skin site are important considerations. Traditional microintegration technologies, such as system-in-package and system-on-chip, typically create lumped aggregations of components. In this paper, the flat architectural platform of a multiparameter sensor system is presented with microcircuitry distributed across multiple stacked layers that can be easily bent to fit body contours. The silicone-encapsulated fabrication of a thin foldable polyimide substrate with distributed surface-mount electronics is demonstrated. The measured performance results are discussed with a particular focus on the assessment of vibration-sensing elements after integration into this type of system has been described.

[1]  Robert Langer,et al.  A BioMEMS review: MEMS technology for physiologically integrated devices , 2004, Proceedings of the IEEE.

[2]  Robert S. Keynton,et al.  Integrated electrochemical detection for lab on a chip analytical microsystems , 2001, Proceedings of the Fourteenth Biennial University/Government/Industry Microelectronics Symposium (Cat. No.01CH37197).

[3]  I. Starr,et al.  Twenty‐Year Studies with the Ballistocardiograph: The Relation between the Amplitude of the First Record of "Healthy" Adults and Eventual Mortality and Morbidity from Heart Disease , 1961 .

[4]  B. Kaminska,et al.  Development of a Novel Contactless Mechanocardiograph Device , 2008, International journal of telemedicine and applications.

[5]  A. Leung,et al.  Micromachined accelerometer with no proof mass , 1997, International Electron Devices Meeting. IEDM Technical Digest.

[6]  Benny P. L. Lo,et al.  BODY SENSOR NETWORK – A WIRELESS SENSOR PLATFORM FOR PERVASIVE HEALTHCARE MONITORING , 2005 .

[7]  J. Alihanka,et al.  A new method for long-term monitoring of the ballistocardiogram, heart rate, and respiration. , 1981, The American journal of physiology.

[8]  Jichun Zhang,et al.  Highly Adaptive Transducer Interface Circuit for Multiparameter Microsystems , 2007, IEEE Transactions on Circuits and Systems I: Regular Papers.

[9]  Kenneth S. Kundert,et al.  Design of mixed-signal systems-on-a-chip , 2000, IEEE Trans. Comput. Aided Des. Integr. Circuits Syst..

[10]  Lei Wang,et al.  An integrated sensor microsystem for industrial and biomedical applications , 2002, IMTC/2002. Proceedings of the 19th IEEE Instrumentation and Measurement Technology Conference (IEEE Cat. No.00CH37276).

[11]  T. Kenny,et al.  A high-performance planar piezoresistive accelerometer , 2000, Journal of Microelectromechanical Systems.

[12]  Ying Bai,et al.  An ultra-wearable, wireless, low power ECG monitoring system , 2006, 2006 IEEE Biomedical Circuits and Systems Conference.

[13]  D. Salerno,et al.  Seismocardiography : a new technique for recording cardiac vibrations. Concept, method, and initial observations , 1990 .

[14]  M. Esashi,et al.  Three-axis Capacitive Accelerometer With Uniform Axial Sensitivities , 1995, Proceedings of the International Solid-State Sensors and Actuators Conference - TRANSDUCERS '95.

[15]  G. Parati,et al.  Wearable Seismocardiography , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[16]  P H Gregson,et al.  Sternal acceleration ballistocardiography and arterial pressure wave analysis to determine stroke volume. , 1999, Clinical and investigative medicine. Medecine clinique et experimentale.

[17]  Neil M. White,et al.  Intelligent Sensor Systems , 1994 .