Transient bradycardia associated with extradural blood patch after inadvertent dural puncture in parturients.

We have studied prospectively 10 ASA I or II postpartum patients after inadvertent dural puncture during labour. An extradural blood patch (autologous blood 15 ml) was performed within 18 h of delivery, with continuous EEG, upper facial EMG (Datex: Anesthesia and Brain Activity Monitor), pulse oximetry and heart rate measurement before, during and for 30 min after extradural injection. Non-invasive arterial pressure measurements (Dinamap) were recorded at 5-min intervals. After extradural blood patch, a statistically significant (Student's t test, P < 0.05) decrease in heart rate, from a mean baseline of 88.6 (SD 7.31) beat min-1 to 51.3 (7.6) beat min-1, occurred within 122.6 (16.9) s from the time of the EBP. Bradycardia was observed for a mean duration of 12.4 (1.1) s. Upper facial EMG, EEG, SpO2 and arterial pressure did not change.

[1]  M. Ramsay,et al.  Epidural injection does cause an increase in CSF pressure. , 1991, Anesthesia and analgesia.

[2]  C. Leicht,et al.  Postpartum seizure after epidural blood patch and intravenous caffeine sodium benzoate. , 1989, Anesthesiology.

[3]  M Paloheimo,et al.  Quantitative surface electromyography (qEMG): applications in anaesthesiology and critical care. , 1990, Acta anaesthesiologica Scandinavica. Supplementum.

[4]  P. Barrington,et al.  Effects of free radicals on the electrophysiological function of cardiac membranes. , 1990, Free radical biology & medicine.

[5]  M. Symons Formation of radicals by mechanical processes. , 1988, Free radical research communications.

[6]  H. Dunford,et al.  Free radicals in iron-containing systems. , 1987, Free radical biology & medicine.