Vesiculopustular eruption of ulcerative colitis.

Many cutaneous disorders that have been described in association with ulcerative colitis (UC), including certain pustular eruptions, probably represent early, evolving lesions of pyoderma gangrenosum (PG). Several nonspecific, often poorly delineated pustular eruptions apparently unrelated to pyoderma gangrenosum have also been reported to occur with ulcerative colitis. A patient had an evanescent, vesiculopustular eruption with a course paralleling that of his UC. Histologic examination of biopsy material from the skin revealed intraepidermal and subcorneal neutrophilic abscess formation and a mixed dermal, perivascular inflammatory cell infiltrate with notable sparing of the follicles. An IgG deposition in a bandlike pattern was identified at the dermoepidermal junction by direct immunofluorescence microscopy. This vesiculopustular eruption may represent a distinct entity or another case or variant of similar pustular eruptions previously described in association with UC.

[1]  F. Greenway,et al.  Cutaneous lesions after intestinal bypass. , 1980, Annals of internal medicine.

[2]  R. S. Basler Ulcerative colitis and the skin. , 1976, The Medical clinics of North America.

[3]  J. Kirsner The local and systemic complications of inflammatory bowel disease. , 1979, JAMA.

[4]  R. J. Reitemeier,et al.  An unusual extracolonic manifestation of chronic ulcerative colitis , 1978, Diseases of the colon and rectum.

[5]  H. Perry,et al.  A diffuse pustular eruption associated with ulcerative colitis. , 1978, Archives of dermatology.

[6]  G. Tijtgat,et al.  Inflammatory bowel disease: cutaneous manifestations. , 1978, Comprehensive therapy.

[7]  S. Winawer,et al.  DERMATOLOGIC ABNORMALITIES ASSOCIATED WITH GASTROINTESTINAL MALIGNANT AND PREMALIGNANT DISEASES , 1978, International journal of dermatology.

[8]  Callen Jp,et al.  Pyoderma gangrenosum--a literature review. , 1978 .

[9]  H. Dubin,et al.  Ulcerative colitis and the skin. , 1980, Archives of dermatology.

[10]  Dantzig Pi Letter: Pyoderma gangrenosum. , 1975 .

[11]  A. L. Macmillan Generalised pustular drug rash. , 1973, Dermatologica.

[12]  D. Stevanović PUSTULAR ERUPTION WITH EOSINOPHILIC ABSCESSES , 1971, British Journal of Dermatology.

[13]  M. L. Johnson,et al.  Skin lesions in ulcerative colitis. , 1969, Gut.

[14]  L. Forman The skin and the colon. , 1966, Transactions of the St. John's Hospital Dermatological Society.

[15]  S. Truelove,et al.  The course and prognosis of ulcerative colitis , 1963, Gut.

[16]  M. L. Kelley Skin lesions associated with chronic ulcerative colitis , 1962, The American journal of digestive diseases.

[17]  M. Samitz,et al.  Skin lesions in association with ulcerative colitis. , 1951, Gastroenterology.

[18]  Sloan Wp,et al.  Life histories of patients with chronic ulcerative colitis: a review of 2,000 cases. , 1950 .

[19]  J. Kirsner,et al.  Pyoderma gangrenosum in chronic non-specific ulcerative colitis; a report of three cases. , 1948, American Journal of Medicine.

[20]  Ricketts We,et al.  Complications of chronic non-specific ulcerative colitis. , 1946 .

[21]  J. A. Bargen,et al.  EXTENSIVE ARTERIAL AND VENOUS THROMBOSIS COMPLICATING CHRONIC ULCERATIVE COLITIS , 1936 .