Intracerebroventricular Delivery as a Safe, Long-Term Route of Drug Administration.

[1]  T. Mccauley,et al.  Pharmacokinetics and Bioavailability of a Therapeutic Enzyme (Idursulfase) in Cynomolgus Monkeys after Intrathecal and Intravenous Administration , 2015, PloS one.

[2]  J. Cooper,et al.  Nonclinical evaluation of CNS-administered TPP1 enzyme replacement in canine CLN2 neuronal ceroid lipofuscinosis. , 2015, Molecular genetics and metabolism.

[3]  Alexander V Kabanov,et al.  Agile delivery of protein therapeutics to CNS. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[4]  M. Souweidane,et al.  Safety profile of long‐term intraventricular access devices in pediatric patients receiving radioimmunotherapy for central nervous system malignancies , 2014, Pediatric blood & cancer.

[5]  I. Slavc,et al.  Safety of Ommaya reservoirs in children with brain tumors: a 20-year experience with 5472 intraventricular drug administrations in 98 patients , 2014, Journal of Neuro-Oncology.

[6]  C. O’Neill,et al.  Recombinant human tripeptidyl peptidase-1 infusion to the monkey CNS: safety, pharmacokinetics, and distribution. , 2014, Toxicology and applied pharmacology.

[7]  G. Iotti,et al.  Intraventricular or intrathecal colistin for the treatment of central nervous system infections caused by multidrug-resistant Gram-negative bacteria , 2014, Expert review of anti-infective therapy.

[8]  P. Mead,et al.  Ommaya reservoir infections: a 16-year retrospective analysis. , 2014, The Journal of infection.

[9]  D. Suki,et al.  Ommaya reservoir-related infections: clinical manifestations and treatment outcomes. , 2014, The Journal of infection.

[10]  W. Jäger,et al.  Pharmacokinetics and Toxicity of Intrathecal Liposomal Cytarabine in Children and Adolescents Following Age-Adapted Dosing , 2014, Clinical Pharmacokinetics.

[11]  Jimmie T. Boyett,et al.  A phase‐1 pharmacokinetic optimal dosing study of intraventricular topotecan for children with neoplastic meningitis: A pediatric brain tumor consortium study , 2013, Pediatric blood & cancer.

[12]  R. Advani,et al.  Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma. , 2011, Blood.

[13]  R. Raffa,et al.  Intracerebroventricular opioids for intractable pain. , 2012, British journal of clinical pharmacology.

[14]  A. Fischman,et al.  Delivery of proteins to CNS as seen and measured by positron emission tomography , 2012, Drug Delivery and Translational Research.

[15]  B. Yin,et al.  Effects of the implantation of Ommaya reservoir in children with tuberculous meningitis hydrocephalus: a preliminary study , 2012, Child's Nervous System.

[16]  Rishi K Wadhwa,et al.  Stereotactic Placement of Ventricular Catheters: Does It Affect Proximal Malfunction Rates? , 2012, Stereotactic and Functional Neurosurgery.

[17]  A. Fischman,et al.  CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder , 2012, PloS one.

[18]  S. Bunting,et al.  Intrathecal tripeptidyl-peptidase 1 reduces lysosomal storage in a canine model of late infantile neuronal ceroid lipofuscinosis. , 2011, Molecular genetics and metabolism.

[19]  Mark D. Johnson,et al.  Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. , 2011, Journal of neurosurgery.

[20]  Zhiguo Lin,et al.  Stereotatic implantation of Ommaya reservoir in the management of brain abscesses , 2011, British journal of neurosurgery.

[21]  J. Joo,et al.  Chemoport with a non-collapsible chamber as a replacement for an Ommaya reservoir in the treatment of leptomeningeal carcinomatosis , 2011, Acta Neurochirurgica.

[22]  Danica Stanimirovic,et al.  Engaging neuroscience to advance translational research in brain barrier biology , 2011, Nature Reviews Neuroscience.

[23]  R. Assaker,et al.  Complications related to the placement of an intraventricular chemotherapy device , 2011, Journal of Neuro-Oncology.

[24]  H. Vogel,et al.  Liposomal cytarabine for central nervous system embryonal tumors in children and young adults , 2011, Journal of Neuro-Oncology.

[25]  Javed Ali,et al.  Strategy for effective brain drug delivery. , 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[26]  L. D. de Vries,et al.  Ventricular Reservoir Punctures Performed by Nurses: An Improvement in Quality of Care , 2010, Neonatal Network.

[27]  W. Sly,et al.  New strategies for enzyme replacement therapy for lysosomal storage diseases. , 2010, Rejuvenation research.

[28]  R. Gabathuler,et al.  Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases , 2010, Neurobiology of Disease.

[29]  I. Slavc,et al.  Pharmacokinetics and Safety of Intrathecal Liposomal Cytarabine in Children Aged <3 Years , 2009, Clinical pharmacokinetics.

[30]  M. Chamberlain,et al.  Neoplastic meningitis: survival as a function of cerebrospinal fluid cytology. , 2009, Cancer.

[31]  F. Ahmad,et al.  CNS drug delivery systems: novel approaches. , 2009, Recent patents on drug delivery & formulation.

[32]  B. Eriksson,et al.  Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development , 2009, Clinical pharmacokinetics.

[33]  D. Rutledge,et al.  Management of adult patients receiving intraventricular chemotherapy for the treatment of leptomeningeal metastasis. , 2008, Clinical journal of oncology nursing.

[34]  G. Broggi,et al.  Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival? , 2008, Journal of Neuro-Oncology.

[35]  R. Hughes.  Patient Safety and Quality: An Evidence-Based Handbook for Nurses , 2008 .

[36]  N. Shinoura,et al.  Navigation-guided Ommaya reservoir placement: implications for the treatment of leptomeningeal metastases. , 2007, Minimally invasive neurosurgery : MIN.

[37]  M. Mcentee,et al.  Intrathecal enzyme replacement therapy: successful treatment of brain disease via the cerebrospinal fluid. , 2007, Molecular genetics and metabolism.

[38]  W. Boogerd,et al.  [Guideline 'Leptomeningeal metastases of solid tumours']. , 2007, Nederlands tijdschrift voor geneeskunde.

[39]  L. D. de Vries,et al.  Incidence of infections of ventricular reservoirs in the treatment of post-haemorrhagic ventricular dilatation: a retrospective study (1992–2003) , 2006, Archives of Disease in Childhood - Fetal and Neonatal Edition.

[40]  P. Adamson,et al.  Intrathecal mafosfamide: a preclinical pharmacology and phase I trial. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[41]  M. Bilsky,et al.  Neurosurgical interventions for leptomeningeal tumor. , 2005, Cancer treatment and research.

[42]  D. Prayer,et al.  Feasibility of Long-Term Intraventricular Therapy with Mafosfamide (n = 26) and Etoposide (n = 11): Experience in 26 Children With Disseminated Malignant Brain Tumors , 2003, Journal of Neuro-Oncology.

[43]  J. Tonn,et al.  Reservoir systems for intraventricular chemotherapy , 1998, Journal of Neuro-Oncology.

[44]  J. Hainfellner,et al.  Intrathecal mafosfamide therapy for pediatric brain tumors with meningeal dissemination , 1998, Journal of Neuro-Oncology.

[45]  A. Murasawa,et al.  Diagnosis and treatment of patients with meningeal carcinomatosis , 1992, Journal of Neuro-Oncology.

[46]  K. Ikenaka,et al.  Clinical Trial of Intrathecal Administration of 5-fluoro-2′-deoxyuridine for Treatment of Meningeal Dissemination of Malignant Tumors , 2004, Journal of Neuro-Oncology.

[47]  R. Fimmers,et al.  Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[48]  R. Edwards,et al.  Routine Placement of a Ventricular Reservoir at Endoscopic Third Ventriculostomy , 2003, Neurosurgery.

[49]  A. Misra,et al.  Drug delivery to the central nervous system: a review. , 2003, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

[50]  T. Siegal.  Toxicity of treatment for neoplastic meningitis , 2003, Current oncology reports.

[51]  R. Fimmers,et al.  Combined systemic and intraventricular chemotherapy in primary CNS lymphoma: a pilot study , 2001, Journal of neurology, neurosurgery, and psychiatry.

[52]  G. Cinalli,et al.  Treatment of post-haemorrhage ventricular dilatation with an Ommaya's reservoir: management and outcome of 64 preterm infants , 2001, Child's Nervous System.

[53]  R. Riccardi,et al.  Intrathecal Chemotherapy With Antineoplastic Agents in Children , 2001, Paediatric drugs.

[54]  J. Vles,et al.  Subcutaneous ventricular catheter reservoir and ventriculoperitoneal drain-related infections in preterm infants and young children. , 2000, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[55]  G. Hortobagyi,et al.  Phase II trial and pharmacokinetic evaluation of cytosine arabinoside for leptomeningeal metastases from breast cancer , 2000, Cancer Chemotherapy and Pharmacology.

[56]  A. Bout,et al.  Distribution of recombinant adenovirus in the cerebrospinal fluid of nonhuman primates. , 1999, Human gene therapy.

[57]  M. Kosier,et al.  Nursing management of patients with an implanted Ommaya reservoir. , 1999, Clinical journal of oncology nursing.

[58]  G. Broggi,et al.  Locally delivered chemotherapy and repeated surgery can improve survival in glioblastoma patients , 1999, The Italian Journal of Neurological Sciences.

[59]  R. Coleman,et al.  Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[60]  M. Chamberlain,et al.  Complications associated with intraventricular chemotherapy in patients with leptomeningeal metastases. , 1997, Journal of neurosurgery.

[61]  J. McComb,et al.  Outcome for preterm infants with germinal matrix hemorrhage and progressive hydrocephalus. , 1997, Neurosurgery.

[62]  J. Hainfellner,et al.  Reversible occlusion shunt for intraventricular chemotherapy in shunt-dependent brain tumor patients. , 1997, Pediatric hematology and oncology.

[63]  R. L. Sinkowitz,et al.  Status of tuberculosis infection control programs at United States hospitals, 1989 to 1992. APIC. Association for Professionals in Infection Control and Epidemiology. , 1996, American journal of infection control.

[64]  G. Fountzilas,et al.  Intraventricular administration of morphine for control of intractable cancer pain in 90 patients. , 1996, Neurosurgery.

[65]  F. Mosteller,et al.  Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. , 2013, The Cochrane database of systematic reviews.

[66]  Y. Lazorthes,et al.  Intracerebroventricular administration of morphine for control of irreducible cancer pain. , 1995, Neurosurgery.

[67]  B. Bell,et al.  Comparison of rates of infection of two methods of emergency ventricular drainage. , 1995, Journal of neurology, neurosurgery, and psychiatry.

[68]  M. Scerrati,et al.  Intrathecal chemotherapy for treatment of overt meningeal leukemia: comparison between intraventricular and traditional intralumbar route. , 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

[69]  J. Clancey.  Using a ventricular reservoir to instill amphotericin B. , 1994, The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses.

[70]  T. Cramond,et al.  Intraventricular morphine for intractable pain of advanced cancer. , 1993, Journal of pain and symptom management.

[71]  M. Chamberlain,et al.  Involved-field radiotherapy and intra-Ommaya methotrexate/cytarabine in patients with AIDS-related lymphomatous meningitis. , 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[72]  J. Hatton,et al.  Vancomycin Administration into the Cerebrospinal Fluid: A Review , 1993, The Annals of pharmacotherapy.

[73]  M. Lishner,et al.  Experience with Ommaya Reservoir in 120 Consecutive Patients with Meningeal Malignancy , 1990, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[74]  M. Lishner,et al.  Complications associated with Ommaya reservoirs in patients with cancer. The Princess Margaret Hospital experience and a review of the literature. , 1990, Archives of internal medicine.