Plasma protein haptoglobin modulates renal iron loading.

[1]  N. Andrews.  Anemia of inflammation: the cytokine-hepcidin link. , 2004, The Journal of clinical investigation.

[2]  M. Hentze,et al.  Balancing Acts Molecular Control of Mammalian Iron Metabolism , 2004, Cell.

[3]  M. Wessling-Resnick,et al.  Ferroportin-1 is not upregulated in copper-deficient mice. , 2004, The Journal of nutrition.

[4]  Tomas Ganz,et al.  Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. , 2003, Blood.

[5]  G. Pasterkamp,et al.  The acute phase protein haptoglobin is locally expressed in arthritic and oncological tissues , 2003, International journal of experimental pathology.

[6]  E. Beutler,et al.  Haptoglobin polymorphism and iron homeostasis. , 2002, Clinical chemistry.

[7]  L. Silengo,et al.  Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis. , 2002, Blood.

[8]  E. Christensen,et al.  Megalin and cubilin: multifunctional endocytic receptors , 2002, Nature Reviews Molecular Cell Biology.

[9]  S. Moestrup,et al.  CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma. , 2002, The international journal of biochemistry & cell biology.

[10]  F. Altruda,et al.  Hemopexin: structure, function, and regulation. , 2002, DNA and cell biology.

[11]  Maria Allhorn,et al.  Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties. , 2002, Blood.

[12]  I. Rusyn,et al.  Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo. , 2002, American journal of physiology. Renal physiology.

[13]  J. Fyfe,et al.  Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin. , 2002, Journal of the American Society of Nephrology : JASN.

[14]  J. Alexander,et al.  Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes. , 2002, American journal of physiology. Renal physiology.

[15]  L. Silengo,et al.  The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading , 2002, The Journal of cell biology.

[16]  M. Vos,et al.  Haptoglobin phenotype 2-2 overrepresentation in Cys282Tyr hemochromatotic patients. , 2001, Journal of hepatology.

[17]  S. K. Lim,et al.  Haptoglobin, an inflammation-inducible plasma protein , 2001, Redox report : communications in free radical research.

[18]  B. Hainque,et al.  Comparison of bathophenanthroline sulfonate and ferene as chromogens in colorimetric measurement of low hepatic iron concentration. , 2001, Clinical chemistry.

[19]  N. Andrews,et al.  Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. , 2001, Human molecular genetics.

[20]  S. Moestrup,et al.  Identification of the haemoglobin scavenger receptor , 2001, Nature.

[21]  H. Neels,et al.  The haptoglobin 2-2 phenotype affects serum markers of iron status in healthy males. , 2000, Clinical chemistry.

[22]  Y. Wang,et al.  Haptoglobin reduces renal oxidative DNA and tissue damage during phenylhydrazine-induced hemolysis. , 2000, Kidney international.

[23]  F. Costantini,et al.  Increased susceptibility in Hp knockout mice during acute hemolysis. , 1998, Blood.

[24]  J. Osada,et al.  Internalization study using EDTA-prepared hepatocytes for receptor-mediated endocytosis of haemoglobin-haptoglobin complex. , 1998, The international journal of biochemistry & cell biology.

[25]  M. D. De Buyzere,et al.  Congenital anhaptoglobinemia versus acquired hypohaptoglobinemia. , 1998, Blood.

[26]  W. Sly,et al.  HFE gene knockout produces mouse model of hereditary hemochromatosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. D’Armiento,et al.  Tissue, temporal and inducible expression pattern of haptoglobin in mice. , 1997, Gene.

[28]  R. Colvin,et al.  Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. , 1996, The Journal of clinical investigation.

[29]  R. Zager,et al.  Rhabdomyolysis and myohemoglobinuric acute renal failure. , 1996, Kidney international.

[30]  R. Zager,et al.  Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury. , 1995, Kidney international.

[31]  R. Hoffman,et al.  Hematology: Basic Principles and Practice , 1995 .

[32]  H. Jacob,et al.  Cytochrome P-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[33]  S. Taketani,et al.  Expression of haptoglobin receptors in human hepatoma cells. , 1992, Biochimica et biophysica acta.

[34]  H. Nakajima,et al.  Catabolism of hemoglobin-haptoglobin complex in microsome subfractions. , 1992, Chemical & pharmaceutical bulletin.

[35]  H. Nakajima,et al.  Intrahepatocellular site of the catabolism of heme and globin moiety of hemoglobin-haptoglobin after intravenous administration to rats. , 1988, The Journal of biological chemistry.

[36]  B. Hedlund,et al.  Role of iron in postischemic renal injury in the rat. , 1988, Kidney international.

[37]  M. Paller.  Hemoglobin- and myoglobin-induced acute renal failure in rats: role of iron in nephrotoxicity. , 1988, The American journal of physiology.

[38]  S. Shah,et al.  Evidence suggesting a role for hydroxyl radical in glycerol-induced acute renal failure. , 1988, The American journal of physiology.

[39]  P. De Meyts,et al.  A rapid method for the preparation of 125I-labelled human growth hormone for receptor studies, using reverse-phase high performance liquid chromatography. , 1986, Biochemical and biophysical research communications.

[40]  H. Nakajima,et al.  Kinetic aspects of hemoglobin.haptoglobin-receptor interaction in rat liver plasma membranes, isolated liver cells, and liver cells in primary culture. , 1982, Journal of Biological Chemistry.

[41]  A. Manoharan.  Congenital haptoglobin deficiency. , 1997, Blood.