Accelerating precision medicine through genetic and genomic big data analysis.

[1]  Yuchao Zhang,et al.  Distinguishing three subtypes of hematopoietic cells based on gene expression profiles using a support vector machine. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[2]  Tao Liu,et al.  Inferring anatomical therapeutic chemical (ATC) class of drugs using shortest path and random walk with restart algorithms. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[3]  Zhi Wei,et al.  Coexpression network analysis identifies transcriptional modules associated with genomic alterations in neuroblastoma. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[4]  Yan Suo,et al.  Identification of genes related to proliferative diabetic retinopathy through RWR algorithm based on protein-protein interaction network. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[5]  Olaf Wolkenhauer,et al.  Unveiling network-based functional features through integration of gene expression into protein networks. , 2018, Biochimica et biophysica acta. Molecular basis of disease.

[6]  R. Nussinov,et al.  Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[7]  Shaopeng Wang,et al.  Identification of the functional alteration signatures across different cancer types with support vector machine and feature analysis. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[8]  Q. Zou,et al.  Network-based method for mining novel HPV infection related genes using random walk with restart algorithm. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[9]  P. Scheet,et al.  Integrated case-control and somatic-germline interaction analyses of melanoma susceptibility genes. , 2018, Biochimica et biophysica acta. Molecular basis of disease.

[10]  Baofeng Lian,et al.  Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity. , 2018, Biochimica et biophysica acta. Molecular basis of disease.

[11]  Florian S. Dreyer,et al.  A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy. , 2018, Biochimica et biophysica acta. Molecular basis of disease.

[12]  Fei Yuan,et al.  Prediction of potential drivers connecting different dysfunctional levels in lung adenocarcinoma via a protein-protein interaction network. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[13]  R. Nussinov,et al.  Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[14]  Mark P. Styczynski,et al.  Metabolic modeling helps interpret transcriptomic changes during malaria. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[15]  Tao Huang,et al.  Predicting and analyzing early wake-up associated gene expressions by integrating GWAS and eQTL studies. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[16]  Yixue Li,et al.  Systematic identification of rabbit LncRNAs reveals functional roles in atherosclerosis. , 2018, Biochimica et biophysica acta. Molecular basis of disease.

[17]  Hongyu Zhao,et al.  Identification of human circadian genes based on time course gene expression profiles by using a deep learning method. , 2017, Biochimica et biophysica acta. Molecular basis of disease.