Cybernetic Modeling for Bioreaction Engineering

In research on bacteria metabolism we have indeed much the same position as an observer trying to gain an idea of the life of a household by careful scrutiny of the persons and material arriving or leaving the house; we keep accurate records of the foods and commodities left at the door and patiently examine the contents of the dust-bin and endeavour to deduce from such data the events occurring within the closed doors. (Marjorie Stephenson, 1930)

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