Enhancement of the surface expression of tumor necrosis factor α (TNFα) but not the p55 TNFα receptor in the THP-1 monocytic cell line by matrix metalloprotease inhibitors

[1]  M. Covington,et al.  The fate of pro-TNF-alpha following inhibition of metalloprotease-dependent processing to soluble TNF-alpha in human monocytes. , 1997, Journal of immunology.

[2]  S. Targan,et al.  A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease , 1997 .

[3]  G. Kollias,et al.  A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling , 1997, European journal of immunology.

[4]  M. T. Brewer,et al.  Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases* , 1997, The Journal of Biological Chemistry.

[5]  G. Chaudhri.  Differential regulation of biosynthesis of cell surface and secreted TNF‐α in LPS‐stimulated murine macrophages , 1997, Journal of leukocyte biology.

[6]  G. Kollias,et al.  Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice , 1997, European journal of immunology.

[7]  L. Moldawer,et al.  A MATRIX METALLOPROTEINASE INHIBITOR PREVENTS PROCESSING OF TUMOR NECROSIS FACTOR α (TNFα) AND ABROGATES ENDOTOXIN‐INDUCED LETHALITY , 1997 .

[8]  S. Roman-Roman,et al.  A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells. , 1997, Cytokine.

[9]  S. Roman-Roman,et al.  Partial purification and characterization of a tumor necrosis factor‐α converting activity , 1997 .

[10]  M. Lambert,et al.  Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α , 1997, Nature.

[11]  Nicole Nelson,et al.  A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells , 1997, Nature.

[12]  S. Narula,et al.  Purification of ADAM 10 from bovine spleen as a TNFα convertase , 1997 .

[13]  J. Vauthey,et al.  Involvement of 26-kDa cell-associated TNF-alpha in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor. , 1997, Journal of immunology.

[14]  J. Dayer,et al.  Expression and cleavage of tumor necrosis factor‐α and tumor necrosis factor receptors by human monocytic cell lines upon direct contact with stimulated T cells , 1996, European journal of immunology.

[15]  Y. Okada,et al.  Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP. , 1996, Biochemical and biophysical research communications.

[16]  M. Feldmann,et al.  Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF alpha processing in RA synovial membrane cell cultures. , 1996, The Journal of clinical investigation.

[17]  V. Pistoia,et al.  Tumor necrosis factor receptor p75 correlates better than p55 with disease activity in juvenile rheumatoid arthritis: comment on the article by Mangge et al. , 1996, Arthritis and rheumatism.

[18]  M. Sormani,et al.  Serum p55 and p75 tumour necrosis factor receptors as markers of disease activity in juvenile chronic arthritis. , 1996, Annals of the rheumatic diseases.

[19]  G. Kollias,et al.  Dissection of the pathologies induced by transmembrane and wild‐type tumor necrosis factor in transgenic mice , 1996, Journal of leukocyte biology.

[20]  R. Maini,et al.  Anti-cytokine therapy in rheumatoid arthritis. , 1995, Bailliere's clinical rheumatology.

[21]  T G Wolfsberg,et al.  ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell- matrix interactions , 1995, The Journal of cell biology.

[22]  U. Gullberg,et al.  Metalloproteases and Serineproteases are Involved in the Cleavage of the Two Tumour Necrosis Factor (TNF) Receptors to Soluble Forms in the Myeloid Cell Lines U‐937 and THP‐1 , 1995, Scandinavian journal of immunology.

[23]  P. Vandenabeele,et al.  Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor (*) , 1995, The Journal of Biological Chemistry.

[24]  Wood,et al.  Matrix metalloproteinases and processing of pro‐TNF‐α , 1995, Journal of leukocyte biology.

[25]  G. Kingsley,et al.  The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis. , 1995, British journal of rheumatology.

[26]  R. Black,et al.  A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes , 1995, The Journal of experimental medicine.

[27]  J. Woody,et al.  Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis , 1994, The Lancet.

[28]  J. Woody,et al.  Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis , 1994, The Lancet.

[29]  M. Hung,et al.  Hyperthermia enhances the cytotoxicity of National Institutes of Health 3T3 cells transfected with a noncleavable transmembrane pro-tumor necrosis factor deletion mutant. , 1994, Journal of Immunotherapy with Emphasis on Tumor Immunology.

[30]  R. Bast,et al.  Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor , 1994, Nature.

[31]  A. H. Drummond,et al.  Processing of tumour necrosis factor-α precursor by metalloproteinases , 1994, Nature.

[32]  M. Gerhart,et al.  Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing , 1994, Nature.

[33]  J. Ghrayeb,et al.  Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. , 1993, Arthritis and rheumatism.

[34]  T. Gatanaga,et al.  Mechanism of release of soluble forms of tumor necrosis factor/lymphotoxin receptors by phorbol myristate acetate-stimulated human THP-1 cells in vitro. , 1993, Journal of immunology.

[35]  L. Gooding,et al.  A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact , 1990, Cell.

[36]  A. Cerami,et al.  Processing of newly synthesized cachectin/tumor necrosis factor in endotoxin-stimulated macrophages. , 1990, Biochemistry.

[37]  A. H. Drummond,et al.  Recent advances in matrix metalloproteinase inhibitor research , 1996 .

[38]  G. Kollias,et al.  Transmembrane TNF is sufficient to induce localized tissue toxicity and chronic inflammatory arthritis in transgenic mice. , 1996, Journal of inflammation.