Amoxicillin/clavulanic acid-induced pemphigus vulgaris: case report.

Drug-induced pemphigus is a well-established variety of pemphigus, presenting with clinical and histopathologic features identical to idiopathic form. Medical history plays a fundamental role in the diagnosis of drug-induced pemphigus. A large variety of drugs have been implicated in its pathogenesis and they may induce acantholysis via biochemical and/or immune mechanism. We present a case of a 69-year-old woman affected by amoxicillin/clavulanic acid-induced pemphigus and discuss its pathogenetic mechanism.

[1]  Manfred S. Green,et al.  Pemphigus variant associated with penicillin use: a case-cohort study of 363 patients from Israel. , 2007, Archives of dermatology.

[2]  C. Chams‐Davatchi,et al.  Pemphigus and associated environmental factors: a case–control study , 2007, Clinical and experimental dermatology.

[3]  S. Brenner,et al.  Histopathologic findings in drug-induced pemphigus. , 1997, The American Journal of dermatopathology.

[4]  S. Brenner,et al.  Recognition of pemphigus antigens in drug-induced pemphigus vulgaris and pemphigus foliaceus. , 1997, Journal of the American Academy of Dermatology.

[5]  S. Dalac,et al.  [Superficial pemphigus in children. Induction role of amoxicillin?]. , 1991, Annales de dermatologie et de venereologie.

[6]  R. Wolf,et al.  Drug-induced versus drug-triggered pemphigus. , 1991, Dermatologica.

[7]  D. Mutasim,et al.  Drug-induced pemphigus. , 1993, Dermatologic clinics.

[8]  P. Morel,et al.  Pemphigus superficiel de l'enfant. Induction par l'amoxicilline? , 1983 .

[9]  P. Morel,et al.  [Superficial pemphigus in children. Induction by amoxicillin?]. , 1983, Annales de dermatologie et de venereologie.

[10]  V. Ruocco,et al.  An abortive form of pemphigus vulgaris probably induced by penicillin. , 1979, Dermatologica.