The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal

[1]  P. Cramer,et al.  The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity , 2004, BMC Cell Biology.

[2]  S. Nagata,et al.  Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice , 2004, Science.

[3]  T. Sasazuki,et al.  Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor. , 2004, Blood.

[4]  K. Lauber,et al.  Clearance of apoptotic cells: getting rid of the corpses. , 2004, Molecular cell.

[5]  G. Pan,et al.  Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. , 2004, Experimental cell research.

[6]  K. Ravichandran,et al.  Cues for apoptotic cell engulfment: eat-me, don't eat-me and come-get-me signals. , 2003, Trends in cell biology.

[7]  P. Rakic,et al.  Phosphatidylserine Receptor Is Required for Clearance of Apoptotic Cells , 2003, Science.

[8]  K. Gengyo-Ando,et al.  Cell Corpse Engulfment Mediated by C. elegans Phosphatidylserine Receptor Through CED-5 and CED-12 , 2003, Science.

[9]  Jochen Graw,et al.  The genetic and molecular basis of congenital eye defects , 2003, Nature Reviews Genetics.

[10]  J. Jais,et al.  Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina , 2003, Developmental dynamics : an official publication of the American Association of Anatomists.

[11]  Zsuzsa Szondy,et al.  Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[12]  G. Kroemer,et al.  Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3. , 2003, The American journal of pathology.

[13]  Swathi Arur,et al.  Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. , 2003, Developmental cell.

[14]  M. Skipper Human genetics: You must remember this... , 2003, Nature Reviews Genetics.

[15]  A. McMahon,et al.  Branching morphogenesis of the lung: new molecular insights into an old problem. , 2003, Trends in cell biology.

[16]  John Savill,et al.  A blast from the past: clearance of apoptotic cells regulates immune responses , 2002, Nature Reviews Immunology.

[17]  Jayanta Debnath,et al.  The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini , 2002, Cell.

[18]  Eric H. Baehrecke,et al.  How death shapes life during development , 2002, Nature Reviews Molecular Cell Biology.

[19]  Keiko Miwa,et al.  Identification of a factor that links apoptotic cells to phagocytes , 2002, Nature.

[20]  M. Hengartner,et al.  CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration , 2001, Cell.

[21]  V. Fadok,et al.  C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells , 2001, The Journal of experimental medicine.

[22]  V. Fadok,et al.  The phosphatidylserine receptor: a crucial molecular switch? , 2001, Nature Reviews Molecular Cell Biology.

[23]  Paul Scherz,et al.  Functional analysis of secreted and transmembrane proteins critical to mouse development , 2001, Nature Genetics.

[24]  R. Scott,et al.  Phagocytosis and clearance of apoptotic cells is mediated by MER , 2001, Nature.

[25]  W. Wood,et al.  Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos. , 2000, Development.

[26]  P. Mathers,et al.  Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice , 2000, Genesis.

[27]  John Savill,et al.  Corpse clearance defines the meaning of cell death , 2000, Nature.

[28]  V. Fadok,et al.  A receptor for phosphatidylserine-specific clearance of apoptotic cells , 2000, Nature.

[29]  H. Jyonouchi Airway epithelium and apoptosis , 1999, Apoptosis.

[30]  R. Flavell,et al.  Caspase knockouts: matters of life and death , 1999, Cell Death and Differentiation.

[31]  P. Heitzler,et al.  Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. , 1999, Science.

[32]  S. Korsmeyer,et al.  Cell Death in Development , 1999, Cell.

[33]  D. Mevorach,et al.  Complement-dependent Clearance of Apoptotic Cells by Human Macrophages , 1998, The Journal of experimental medicine.

[34]  V. Fadok,et al.  CD36 Is Required for Phagocytosis of Apoptotic Cells by Human Macrophages That Use Either a Phosphatidylserine Receptor or the Vitronectin Receptor (αvβ3) , 1998, The Journal of Immunology.

[35]  V. Fadok,et al.  CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3). , 1998, Journal of immunology.

[36]  A. Schroit,et al.  Characterization of phosphatidylserine-dependent beta2-glycoprotein I macrophage interactions. Implications for apoptotic cell clearance by phagocytes. , 1998, The Journal of biological chemistry.

[37]  Pier Paolo Pandolfi,et al.  Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies , 1998, Nature Genetics.

[38]  A. Devitt,et al.  Human CD14 mediates recognition and phagocytosis of apoptotic cells , 1998, Nature.

[39]  K. Ohashi,et al.  Cell Adhesion to Phosphatidylserine Mediated by a Product of Growth Arrest-specific Gene 6* , 1997, The Journal of Biological Chemistry.

[40]  M. Raff,et al.  Programmed Cell Death in Animal Development , 1997, Cell.

[41]  S Gordon,et al.  Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[42]  D. Davidson,et al.  The role of Pax-6 in eye and nasal development. , 1995, Development.

[43]  J. Rossant,et al.  Notch1 is required for the coordinate segmentation of somites. , 1995, Development.

[44]  H. Bluethmann,et al.  Targeted disruption of the MHC class II Aa gene in C57BL/6 mice. , 1993, International immunology.

[45]  J Savill,et al.  Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. , 1992, The Journal of clinical investigation.

[46]  V. Fadok,et al.  Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. , 1992, Journal of immunology.

[47]  Nobuyuki Itoh,et al.  Tube or not tube: remodeling epithelial tissues by branching morphogenesis. , 2003, Developmental cell.

[48]  C. Paweletz,et al.  Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells , 2003, Nature Immunology.

[49]  Conrad C. Huang,et al.  BayGenomics: a resource of insertional mutations in mouse embryonic stem cells , 2003, Nucleic Acids Res..

[50]  V. Fadok,et al.  Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. , 2002, The Journal of clinical investigation.

[51]  R. Lang,et al.  Early eye development in vertebrates. , 2001, Annual review of cell and developmental biology.

[52]  J. J. Sharp,et al.  The Jackson Laboratory Induced Mutant Resource. , 1994 .

[53]  R. Frank Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support , 1992 .