An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair.

[1]  Rolf Boelens,et al.  Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches. , 2004, Structure.

[2]  H. Timmers,et al.  Repression of Promoter Activity by CNOT2, a Subunit of the Transcription Regulatory Ccr4-Not Complex* , 2004, Journal of Biological Chemistry.

[3]  M. Collart.  Global control of gene expression in yeast by the Ccr4-Not complex. , 2003, Gene.

[4]  M. Muratani,et al.  How the ubiquitin–proteasome system controls transcription , 2003, Nature Reviews Molecular Cell Biology.

[5]  C. Dominguez,et al.  HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. , 2003, Journal of the American Chemical Society.

[6]  Robert Tjian,et al.  Regulating the Regulators Lysine Modifications Make Their Mark , 2003, Cell.

[7]  C. Vandenberg,et al.  Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains , 2002, The EMBO journal.

[8]  C. Hill,et al.  Structural basis of ubiquitylation. , 2002, Current opinion in structural biology.

[9]  G. Theiler,et al.  The Ccr4-Not Complex and yTAF1 (yTafII130p/yTafII145p) Show Physical and Functional Interactions , 2002, Molecular and Cellular Biology.

[10]  M. Tyers,et al.  Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment. , 2002, Molecular cell.

[11]  R. Conaway,et al.  Emerging Roles of Ubiquitin in Transcription Regulation , 2002, Science.

[12]  Y. Xiong,et al.  Activation of UBC5 Ubiquitin-conjugating Enzyme by the RING Finger of ROC1 and Assembly of Active Ubiquitin Ligases by All Cullins* , 2002, The Journal of Biological Chemistry.

[13]  P. Jackson,et al.  The SCF ubiquitin ligase: an extended look. , 2002, Molecular cell.

[14]  S. Elledge,et al.  Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex , 2002, Nature.

[15]  R. Boelens,et al.  Identification of a ubiquitin–protein ligase subunit within the CCR4–NOT transcription repressor complex , 2002, The EMBO journal.

[16]  Zhijian J. Chen,et al.  TAK1 is a ubiquitin-dependent kinase of MKK and IKK , 2001, Nature.

[17]  W. Langdon,et al.  Cbl: many adaptations to regulate protein tyrosine kinases , 2001, Nature Reviews Molecular Cell Biology.

[18]  R. Boelens,et al.  The Structure of the C4C4RING Finger of Human NOT4 Reveals Features Distinct from Those of C3HC4 RING Fingers* , 2001, The Journal of Biological Chemistry.

[19]  H. Y. Liu,et al.  Characterization of CAF4 and CAF16 Reveals a Functional Connection between the CCR4-NOT Complex and a Subset of SRB Proteins of the RNA Polymerase II Holoenzyme* , 2001, The Journal of Biological Chemistry.

[20]  A. Weissman.  Ubiquitin and proteasomes: Themes and variations on ubiquitylation , 2001, Nature Reviews Molecular Cell Biology.

[21]  Zhijian J. Chen,et al.  Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.

[22]  A. Ciechanover,et al.  The ubiquitin system , 2000, Nature Medicine.

[23]  M. Collart,et al.  The TATA-binding protein-associated factor yTafII19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit. , 2000, The Journal of biological chemistry.

[24]  A. Weissman,et al.  RING Finger Proteins Mediators of Ubiquitin Ligase Activity , 2000, Cell.

[25]  Ping Wang,et al.  Structure of a c-Cbl–UbcH7 Complex RING Domain Function in Ubiquitin-Protein Ligases , 2000, Cell.

[26]  S. Reed,et al.  Regulation of Transcription by Ubiquitination without Proteolysis Cdc34/SCFMet30-Mediated Inactivation of the Transcription Factor Met4 , 2000, Cell.

[27]  V. Badarinarayana,et al.  Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. , 2000, Genetics.

[28]  V. Kushnirov.  Rapid and reliable protein extraction from yeast , 2000, Yeast.

[29]  N. V. van Berkum,et al.  Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. , 2000, Nucleic acids research.

[30]  Martin Rechsteiner,et al.  Recognition of the polyubiquitin proteolytic signal , 2000, The EMBO journal.

[31]  P. Howley,et al.  Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. , 1999, Science.

[32]  John J. Wyrick,et al.  Interplay of Positive and Negative Regulators in Transcription Initiation by RNA Polymerase II Holoenzyme , 1998, Molecular and Cellular Biology.

[33]  M. Scheffner,et al.  A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[34]  C. Denis,et al.  The CCR4-NOT complex plays diverse roles in mRNA metabolism. , 2003, Progress in nucleic acid research and molecular biology.

[35]  C. Pickart,et al.  Mechanisms underlying ubiquitination. , 2001, Annual review of biochemistry.

[36]  W. Baumeister,et al.  The 26S proteasome: a molecular machine designed for controlled proteolysis. , 1999, Annual review of biochemistry.