Exploiting GPUs to investigate an inversion method that retrieves cardiac conductivities from potential measurements

Accurate cardiac bidomain conductivity values are essential for realistic simulation of various cardiac electrophysiological phenomena. A method was previously developed that can determine the conductivities from measurements of potential on a multi-electrode array placed on the surface of the heart. These conductivities, as well as a value for fibre rotation, are determined using a mathematical model and a two-pass process that is based on Tikhonov regularisation. Using simulated potentials, to which noise is added, the inversion method was recently shown to retrieve the intracellular conductivities accurately with up to 15% noise and the extracellular conductivities extremely accurately even with 20% noise. Recent work investigated the sensitivity of the

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