Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
暂无分享,去创建一个
P. Dorrestein | V. Nizet | B. Moore | D. Gonzalez | Kazuya Yamanaka | Kirk A Reynolds | R. Kersten | K. Ryan
[1] C. Boddy,et al. The role of transcription in heterologous expression of polyketides in bacterial hosts. , 2013, Natural product reports.
[2] C. Bertelli,et al. Rapid bacterial genome sequencing: methods and applications in clinical microbiology. , 2013, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
[3] H. Schweizer,et al. An Improved Method for oriT-Directed Cloning and Functionalization of Large Bacterial Genomic Regions , 2013, Applied and Environmental Microbiology.
[4] Kai Blin,et al. antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers , 2013, Nucleic Acids Res..
[5] F. Stewart,et al. Direct Cloning, Genetic Engineering, and Heterologous Expression of the Syringolin Biosynthetic Gene Cluster in E. coli through Red/ET Recombineering , 2012, Chembiochem : a European journal of chemical biology.
[6] B. Moore,et al. Flavoenzyme-catalyzed atropo-selective N,C-bipyrrole homocoupling in marinopyrrole biosynthesis. , 2012, Journal of the American Chemical Society.
[7] Rolf Müller,et al. Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting , 2012, Nature Biotechnology.
[8] C. Hutchison,et al. Cloning the Acholeplasma laidlawii PG-8A genome in Saccharomyces cerevisiae as a yeast centromeric plasmid. , 2012, ACS synthetic biology.
[9] Anna Lechner,et al. Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation. , 2011, Chemistry & biology.
[10] H. Brückner,et al. Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems. , 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[11] S. Brady,et al. Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites , 2011, Proceedings of the National Academy of Sciences.
[12] Christophe Corre,et al. Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens , 2011, Proceedings of the National Academy of Sciences.
[13] M. Bibb,et al. Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters , 2011, Microbial biotechnology.
[14] R. Breitling,et al. Synthetic biology in Streptomyces bacteria. , 2011, Methods in enzymology.
[15] S. Brady,et al. Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster. , 2010, Journal of the American Chemical Society.
[16] Paula Y. Calle,et al. Cloning large natural product gene clusters from the environment: Piecing environmental DNA gene clusters back together with TAR , 2010, Biopolymers.
[17] K. Maloney,et al. Lodopyridone, a structurally unprecedented alkaloid from a marine actinomycete. , 2009, Organic letters.
[18] Haruo Ikeda,et al. Genomic basis for natural product biosynthetic diversity in the actinomycetes. , 2009, Natural product reports.
[19] B. Gust. Chapter 7. Cloning and analysis of natural product pathways. , 2009, Methods in enzymology.
[20] Hanlee P. Ji,et al. Next-generation DNA sequencing , 2008, Nature Biotechnology.
[21] M. Berger,et al. The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters , 2008, Molecular microbiology.
[22] G. Challis. Genome Mining for Novel Natural Product Discovery , 2008 .
[23] L. Heide,et al. Assembly and Heterologous Expression of the Coumermycin A1 Gene Cluster and Production of New Derivatives by Genetic Engineering , 2008, Chembiochem : a European journal of chemical biology.
[24] Vladimir Larionov,et al. Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae , 2008, Nature Protocols.
[25] William Fenical,et al. The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp. , 2008, Organic letters.
[26] J. Micklefield,et al. Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis. , 2007, Journal of the American Chemical Society.
[27] Corinna Lange,et al. Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. , 2007, Nature chemical biology.
[28] K. Nguyen,et al. A glutamic acid 3‐methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus , 2006, Molecular microbiology.
[29] Ben Shen,et al. Microbial genomics for the improvement of natural product discovery. , 2006, Current opinion in microbiology.
[30] Richard H. Baltz,et al. Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration? , 2006, Journal of Industrial Microbiology and Biotechnology.
[31] J. Blanchard,et al. The kinetic mechanism of AAC3-IV aminoglycoside acetyltransferase from Escherichia coli. , 2005, Biochemistry.
[32] Rolf Müller,et al. The impact of bacterial genomics on natural product research. , 2005, Angewandte Chemie.
[33] Christopher J. Silva,et al. Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry. , 2005, Microbiology.
[34] M. Bibb,et al. Regulation of secondary metabolism in streptomycetes. , 2005, Current opinion in microbiology.
[35] Rolf Müller,et al. Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. , 2005, Chemistry & biology.
[36] R. Hancock,et al. Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin. , 2004, Chemistry & biology.
[37] Gregory L. Challis,et al. Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[38] G. Challis,et al. PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[39] Jason Micklefield,et al. Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor. , 2002, Chemistry & biology.
[40] M. Watve,et al. How many antibiotics are produced by the genus Streptomyces? , 2001, Archives of Microbiology.
[41] T. Kieser. Practical streptomyces genetics , 2000 .
[42] M. Fernández-Moreno,et al. Characterization of the Pathway-Specific Positive Transcriptional Regulator for Actinorhodin Biosynthesis inStreptomyces coelicolor A3(2) as a DNA-Binding Protein , 1999, Journal of bacteriology.
[43] J. Ishikawa,et al. FramePlot: a new implementation of the frame analysis for predicting protein-coding regions in bacterial DNA with a high G + C content. , 1999, FEMS microbiology letters.
[44] J. Barrett,et al. Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[45] E. Schmidt,et al. Microsclerodermins C-E, antifungal cyclic peptides from the lithistid marine sponges Theonella sp. and Microscleroderma sp , 1998 .
[46] F. Flett,et al. High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes. , 1997, FEMS microbiology letters.
[47] M. Bibb,et al. A novel family of proteins that regulates antibiotic production in streptomycetes appears to contain an OmpR‐like DNA‐binding fold , 1997, Molecular microbiology.
[48] J. Barrett,et al. Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[49] K. Oldenburg,et al. Recombination-mediated PCR-directed plasmid construction in vivo in yeast. , 1997, Nucleic acids research.
[50] M. Bibb,et al. afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2) , 1996, Molecular microbiology.
[51] R. Fleischmann,et al. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. , 1995, Science.
[52] J. Kalinowski,et al. Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum. , 1994, Gene.
[53] I. Kumagai,et al. Effect of a rare leucine codon, TTA, on expression of a foreign gene in Streptomyces lividans. , 1993, Biochimica et biophysica acta.
[54] S. Lin-Chao,et al. High copy number of the pUC plasmid results from a Rom/Rop‐suppressible point mutation in RNA II , 1992, Molecular microbiology.
[55] K. O'Brien,et al. Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. , 1992, Gene.
[56] D. Macneil,et al. Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. , 1992, Gene.
[57] R. Molloy,et al. Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032). , 1988, The Journal of antibiotics.