New targets for heart-failure therapy: endothelin, inflammatory cytokines, and oxidative stress
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[1] OLAND,et al. TREATMENT OF SEPTIC SHOCK WITH THE TUMOR NECROSIS FACTOR RECEPTOR : Fc FUSION PROTEIN C , 2000 .
[2] A. Omran,et al. Increased oxidative stress in patients with congestive heart failure. , 1998, Journal of the American College of Cardiology.
[3] D. Chatel,et al. Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure. , 1998, Circulation.
[4] R. Peshock,et al. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. , 1998, Circulation.
[5] F. Clubb,et al. Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. , 1998, Circulation.
[6] K. Sliwa,et al. Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy , 1998, The Lancet.
[7] D. Wagner,et al. Adenosine inhibits lipopolysaccharide-induced secretion of tumor necrosis factor-alpha in the failing human heart. , 1998, Circulation.
[8] N. Takahashi,et al. Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. , 1998, The Journal of clinical investigation.
[9] M. Creager,et al. Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: potentiation of beta-adrenergic inotropic responsiveness. , 1998, Circulation.
[10] D. Levy,et al. Antioxidant effect of carvedilol and metoprolol in congestive heart failure , 1998 .
[11] J. Cleland,et al. Pulmonary and systemic responses to exogenous endothelin-1 in patients with left ventricular dysfunction. , 1998, Journal of cardiovascular pharmacology.
[12] W. Colucci. Molecular and cellular mechanisms of myocardial failure. , 1997, The American journal of cardiology.
[13] K. Weber,et al. Extracellular matrix remodeling in heart failure: a role for de novo angiotensin II generation. , 1997, Circulation.
[14] P. Galuppo,et al. Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling. , 1997, Circulation.
[15] S. Targan,et al. A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease , 1997 .
[16] A. Koretsky,et al. Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α , 1997 .
[17] F. Lallemand,et al. Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling. , 1997, Circulation.
[18] E. Tindall,et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. , 1997, The New England journal of medicine.
[19] R. Dixon,et al. Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist. , 1997, Journal of Medicinal Chemistry.
[20] M. Oz,et al. Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation? , 1997, Circulation.
[21] Bertram Pitt,et al. Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE) , 1997, The Lancet.
[22] B. Lopez,et al. Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart. , 1997, Coronary artery disease.
[23] S. Goto,et al. Characterization of cytokine and iNOS mRNA expression in situ during the course of experimental autoimmune myocarditis in rats. , 1997, Journal of molecular and cellular cardiology.
[24] S. Targan,et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. , 1997, The New England journal of medicine.
[25] D. Zechner,et al. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. , 1996, The Journal of clinical investigation.
[26] N. Goel,et al. Oxy free radical system in heart failure and therapeutic role of oral vitamin E. , 1996, International journal of cardiology.
[27] B. Pitt,et al. IL-1 beta stimulates superoxide and delayed peroxynitrite production by pulmonary vascular smooth muscle cells. , 1996, The American journal of physiology.
[28] Y. Sugishita,et al. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure , 1996, Nature.
[29] D. Stewart,et al. Human pulmonary circulation is an important site for both clearance and production of endothelin-1. , 1996, Circulation.
[30] M. Matzuk,et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[31] J. Goldhaber. Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes. , 1996, The American journal of physiology.
[32] D. Lalloo,et al. Prevention of Jarisch-Herxheimer reactions by treatment with antibodies against tumor necrosis factor alpha. , 1996, The New England journal of medicine.
[33] P. Singal,et al. Role of oxidative stress in transition of hypertrophy to heart failure. , 1996, Journal of the American College of Cardiology.
[34] S. Opal,et al. Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group. , 1996, The New England journal of medicine.
[35] M. Yacoub,et al. Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy , 1996, The Lancet.
[36] H. Oral,et al. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). , 1996, Journal of the American College of Cardiology.
[37] P. Tsao,et al. Expression of inducible nitric oxide synthase in human heart failure. , 1996, Circulation.
[38] W. Colucci. Myocardial endothelin. Does it play a role in myocardial failure? , 1996, Circulation.
[39] Y. Sugishita,et al. Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart. , 1996, Circulation.
[40] D. Mann,et al. Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart , 1996 .
[41] S. García-Castiñeiras,et al. Increased malondialdehyde in peripheral blood of patients with congestive heart failure. , 1996, American heart journal.
[42] P. Singal,et al. Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. , 1996, The American journal of pathology.
[43] E. Sonnenblick,et al. Stretch-induced programmed myocyte cell death. , 1995, The Journal of clinical investigation.
[44] P. Hunziker,et al. Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure , 1995, The Lancet.
[45] J. Hare,et al. Role of nitric oxide in the regulation of myocardial function. , 1995, Progress in cardiovascular diseases.
[46] N. Takahashi,et al. Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. , 1995, The Journal of clinical investigation.
[47] H. Krum,et al. Role of endothelin in the exercise intolerance of chronic heart failure. , 1995, The American journal of cardiology.
[48] W. Maksymowych,et al. An open study of pentoxifylline in the treatment of severe refractory rheumatoid arthritis. , 1995, The Journal of rheumatology.
[49] K. Swedberg,et al. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group. , 1995, Journal of cardiac failure.
[50] P. Cannon,et al. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. , 1995, The Journal of clinical investigation.
[51] J. Vilček,et al. Interferon-beta induces metalloproteinase mRNA expression in human fibroblasts. Role of activator protein-1. , 1994, The Journal of biological chemistry.
[52] M. Yanagisawa,et al. ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1 , 1994, Cell.
[53] P. Singal,et al. Antioxidant changes in hypertrophied and failing guinea pig hearts. , 1994, The American journal of physiology.
[54] W. Edwards,et al. Endothelin in human congestive heart failure. , 1994, Circulation.
[55] J. McMurray,et al. Evidence of oxidative stress in chronic heart failure in humans. , 1993, European heart journal.
[56] F. Appelbaum,et al. A randomized controlled trial of pentoxifylline for the prevention of regimen-related toxicities in patients undergoing allogeneic marrow transplantation , 1993 .
[57] M. Arakawa,et al. Comparative free radical scavenging action of angiotensin-converting enzyme inhibitors with and without the sulfhydryl radical. , 1993, Pharmacology.
[58] J. Parrillo. Pathogenetic mechanisms of septic shock. , 1993, The New England journal of medicine.
[59] S. Moncada,et al. Nitric oxide synthase activities in human myocardium , 1993, The Lancet.
[60] J. Ferrara,et al. Cytokine dysregulation and acute graft-versus-host disease. , 1992, Blood.
[61] H. Blömer,et al. Ubiquinone (coenzyme Q10) in the long-term treatment of idiopathic dilated cardiomyopathy. , 1992, European heart journal.
[62] Hung‐Yuan Cheng,et al. Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger. , 1992, The Journal of pharmacology and experimental therapeutics.
[63] P. Binkley,et al. Plasma Endothelin Correlates With the Extent of Pulmonary Hypertension in Patients With Chronic Congestive Heart Failure , 1992, Circulation.
[64] K. Chien,et al. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. , 1990, The Journal of biological chemistry.
[65] H. Fillit,et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. , 1990, The New England journal of medicine.
[66] J. McMurray,et al. Evidence for enhanced free radical activity in chronic congestive heart failure secondary to coronary artery disease. , 1990, The American journal of cardiology.
[67] K. Folkers,et al. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. , 1990, The American journal of cardiology.
[68] P. Zabel,et al. OXPENTIFYLLINE IN ENDOTOXAEMIA , 1989, The Lancet.
[69] R. Strieter,et al. Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline , 1988 .
[70] K. Folkers,et al. Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[71] J. McCord,et al. Oxygen-derived free radicals in postischemic tissue injury. , 1985, The New England journal of medicine.