Altered mitochondrial function and genome frequency post exposure to γ-radiation and bystander factors
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[1] P. M. Hwang,et al. The Krebs cycle meets the cell cycle: Mitochondria and the G1–S transition , 2009, Proceedings of the National Academy of Sciences.
[2] Kevin M. Prise,et al. Radiation-induced bystander signalling in cancer therapy , 2009, Nature Reviews Cancer.
[3] William D. Graham,et al. A Disease-causing Point Mutation in Human Mitochondrial tRNAMet Results in tRNA Misfolding Leading to Defects in Translational Initiation and Elongation* , 2008, Journal of Biological Chemistry.
[4] E. Wright,et al. Chromosomal instability in unirradiated hemaopoietic cells induced by macrophages exposed in vivo to ionizing radiation. , 2008, Cancer research.
[5] P. Goswami,et al. Mitochondria-targeted antioxidant enzyme activity regulates radioresistance in human pancreatic cancer cells , 2008, Cancer biology & therapy.
[6] T. Hei,et al. Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects , 2008, British Journal of Cancer.
[7] T. Hei,et al. Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiation-induced bystander effects. , 2008, Cancer research.
[8] Utpal Banerjee,et al. Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint , 2008, Nature Genetics.
[9] C. Mothersill,et al. Bystander signal production and response are independent processes which are cell line dependent , 2008, International journal of radiation biology.
[10] C. Mothersill,et al. Increased Mitochondrial Mass in Cells with Functionally Compromised Mitochondria after Exposure to both Direct γ Radiation and Bystander Factors , 2007, Radiation research.
[11] K. Prise,et al. Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. , 2007, Cancer research.
[12] C. Chi,et al. Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion. , 2007, Mitochondrion.
[13] R. Shin,et al. Analysis of Common Deletion (CD) and a novel deletion of mitochondrial DNA induced by ionizing radiation , 2007, International journal of radiation biology.
[14] Ruifang Niu,et al. Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients , 2007, IUBMB life.
[15] G. Fiskum,et al. A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. , 2006, Cancer research.
[16] T. Hei. Cyclooxygenase‐2 as a signaling molecule in radiation‐induced bystander effect , 2006, Molecular carcinogenesis.
[17] C. Mothersill,et al. The Involvement of Calcium and MAP Kinase Signaling Pathways in the Production of Radiation-Induced Bystander Effects , 2006, Radiation research.
[18] C. Chi,et al. Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer , 2005, Genes, chromosomes & cancer.
[19] K. Yeh,et al. Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer , 2006, BMC Cancer.
[20] D. Brenner,et al. Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[21] G. Faye,et al. Mutations in MTO2 Related to tRNA Modification Impair Mitochondrial Gene Expression and Protein Synthesis in the Presence of a Paromomycin Resistance Mutation in Mitochondrial 15 S rRNA* , 2005, Journal of Biological Chemistry.
[22] C. Mothersill,et al. Mitochondrial DNA point mutations and a novel deletion induced by direct low-LET radiation and by medium from irradiated cells. , 2005, Mutation research.
[23] Yau-Huei Wei,et al. Oxidative Stress‐Induced Depolymerization of Microtubules and Alteration of Mitochondrial Mass in Human Cells , 2005, Annals of the New York Academy of Sciences.
[24] M. Resnick,et al. Impact of mitochondria on nuclear genome stability. , 2005, DNA repair.
[25] V. Bezlepkin,et al. The increase in mitochondrial DNA copy number in the tissues of gamma-irradiated mice. , 2005, Cellular & molecular biology letters.
[26] G. Rutter,et al. Inhibition of Mitochondrial Na (cid:1) -Ca 2 (cid:1) Exchange Restores Agonist-induced ATP Production and Ca 2 (cid:1) Handling in Human Complex I Deficiency* , 2004 .
[27] Emilia Maneiro,et al. Mitochondrial dysfunction in osteoarthritis. , 2004, Mitochondrion.
[28] R. Martuza,et al. Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors. , 2004, Molecular cancer research : MCR.
[29] Joachim Klose,et al. Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice* , 2004, Journal of Biological Chemistry.
[30] C. Mothersill,et al. Bystander Effects in Repair-Deficient Cell Lines , 2004, Radiation research.
[31] C. Hoppel,et al. Ischemia-reperfusion injury in the aged heart: role of mitochondria. , 2003, Archives of biochemistry and biophysics.
[32] K. Pfeiffer,et al. Mitochondrial complex I is deficient in renal oncocytomas. , 2003, Carcinogenesis.
[33] W. Morgan,et al. Persistent oxidative stress in chromosomally unstable cells. , 2003, Cancer research.
[34] Robert W. Taylor,et al. Changes in the human mitochondrial genome after treatment of malignant disease. , 2003, Mutation research.
[35] Jean-Pierre Mazat,et al. Mitochondrial threshold effects. , 2003, The Biochemical journal.
[36] P. Bénit,et al. Assay of mitochondrial respiratory chain complex I in human lymphocytes and cultured skin fibroblasts. , 2003, Biochemical and biophysical research communications.
[37] Peng Huang,et al. Mitochondrial defects in cancer , 2002, Molecular Cancer.
[38] M. Karbowski,et al. Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells. , 2002, Mitochondrion.
[39] D. Turnbull,et al. Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism? , 2002, The Lancet.
[40] Kathy Pfeiffer,et al. Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma. , 2002, Carcinogenesis.
[41] Carmel Mothersill,et al. Relationship between Radiation-Induced Low-Dose Hypersensitivity and the Bystander Effect , 2002, Radiation research.
[42] C. Mothersill,et al. Initiation of Apoptosis in Cells Exposed to Medium from the Progeny of Irradiated Cells: A Possible Mechanism for Bystander-Induced Genomic Instability? , 2002, Radiation research.
[43] P. Reynier,et al. Defective mitochondrial ATP synthesis in oxyphilic thyroid tumors. , 2001, The Journal of clinical endocrinology and metabolism.
[44] D. Zhou,et al. Transcription of the Schizosaccharomyces pombe U2 gene in vivo and in vitro is directed by two essential promoter elements. , 2001, Nucleic acids research.
[45] M. Pfaffl,et al. A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.
[46] C. Mothersill,et al. Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis , 2000, British Journal of Cancer.
[47] Carmel Mothersill,et al. Relative Contribution of Bystander and Targeted Cell Killing to the Low-Dose Region of the Radiation Dose–Response Curve , 2000, Radiation research.
[48] C. Mothersill,et al. Involvement of energy metabolism in the production of ‘bystander effects’ by radiation , 2000, British Journal of Cancer.
[49] B. Lehnert,et al. Factors underlying the cell growth-related bystander responses to alpha particles. , 2000, Cancer research.
[50] M. W. Gray,et al. Evolution of organellar genomes. , 1999, Current opinion in genetics & development.
[51] E H Goodwin,et al. Alpha particles induce the production of interleukin-8 by human cells. , 1999, Radiation research.
[52] J. Taanman,et al. The mitochondrial genome: structure, transcription, translation and replication. , 1999, Biochimica et biophysica acta.
[53] K M Prise,et al. Studies of bystander effects in human fibroblasts using a charged particle microbeam. , 1998, International journal of radiation biology.
[54] J. Little,et al. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. , 1998, Radiation research.
[55] Á. Almeida,et al. A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture. , 1998, Brain research. Brain research protocols.
[56] E. Holme,et al. Threshold expression of the tRNALys A8344G mutation in single muscle fibres , 1997, Neuromuscular Disorders.
[57] E. Wright. Radiation-induced genomic instability in haemopoietic cells. , 1998, International journal of radiation biology.
[58] S. Dimauro,et al. Mitochondrial DNA Mutations and Pathogenesis , 1997, Journal of bioenergetics and biomembranes.
[59] C. Mothersill,et al. Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment. , 1997, Radiation oncology investigations.
[60] C. Mothersill,et al. Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells. , 1997, International journal of radiation biology.
[61] M. Murphy,et al. Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations. , 1996, The Biochemical journal.
[62] I. Nelson,et al. Erratum to “Impaired mitochondrial translation in human myoblasts harbouring the mitochondrial DNA tRNA lysine 8344 A → G (MERRF) mutation: relationship to proportion of mutant mitochondrial DNA” J. Neurol. Sci. 130 (1995) 154–160 , 1995, Journal of the Neurological Sciences.
[63] I. Nelson,et al. Impaired mitochondrial translation in human myoblasts harbouring the mitochondrial DNA tRNA lysine 8344 A → G (MERRF) mutation: relationship to proportion of mutant mitochondrial DNA , 1995, Journal of the Neurological Sciences.
[64] A. Kronenberg,et al. Radiation-induced genomic instability. , 1994, International journal of radiation biology.
[65] Reinhart Heinrich,et al. The kinetic basis of threshold effects observed in mitochondrial diseases: a systemic approach. , 1994, The Biochemical journal.
[66] S. Dimauro,et al. Extremely high levels of mutant mtDNAs co-localize with cytochrome c oxidase-negative ragged-red fibers in patients harboring a point mutation at nt 3243. , 1994, Human molecular genetics.
[67] J. Little,et al. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. , 1992, Cancer research.
[68] I. Nonaka,et al. MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[69] E. Schon,et al. Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. , 1992, Molecular and cellular biology.
[70] S. Dimauro,et al. Mitochondrial diseases. , 1989, Neurologic clinics.
[71] J. DiPaolo,et al. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. , 1988, Carcinogenesis.
[72] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[73] T. Puck,et al. Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells. , 1968, Proceedings of the National Academy of Sciences of the United States of America.