Study on a Multi-Ions Sensing System for Monitoring of Blood Electrolytes With Wireless Home-Care System

This study developed a multi-ions sensing system that includes pH, potassium, sodium, and chloride ion sensors with a wireless home-care system. The pH sensor was based on a tin oxide (SnO )/indium tin oxide (ITO) glass, and the potassium, sodium, and chloride ion sensors were based on the pH sensor with sensing membrane. The tin oxide (SnO) sensing membrane was deposited on indium tin oxide (ITO) substrate using a sputtering system. The sensing membranes of the ion sensors were prepared by mixing poly (vinyl chloride) (PVC), bis (2-ethylhexyl) sebacate (DOS), ionophores, and additives. According to the experimental results, sensitivities of the sensors all were over the value 51 mV/decade. The linear range of pH sensor was between pH2 and pH12, the linear ranges of potassium, sodium, and chloride sensors all were over from 1 mM to 1 M. Therefore, the multi-ions sensing system is suitable for monitoring of blood electrolytes. The correlations of the multi-ion sensors under different test solutions also were discussed. Moreover, this study also investigated sensors module, portable module, Bluetooth module, personal computer (PC) terminal, and portable unit of the wireless home-care system. A graphical measurement interface for data recorded and measurement results displayed was designed by National Instrument Lab-VIEW software. According to the experimental results, the measurement data by the wireless home-care system are near the real values. The wireless home-care system could successfully monitor and transmitted the sensing signals.

[1]  T. Sun,et al.  New Calibration Methods to Eliminate the Non-Ideal Effect of Drift and Hysteresis in All-Solid-State Potassium Electrode , 2011, IEEE Sensors Journal.

[2]  Lawrence C. Chirwa,et al.  Electromagnetic radiation from ingested sources in the human intestine between 150 MHz and 1.2 GHz , 2003, IEEE Transactions on Biomedical Engineering.

[3]  Daeyoung Kim,et al.  SNAIL: an IP-based wireless sensor network approach to the internet of things , 2010, IEEE Wireless Communications.

[4]  Paolo Dario,et al.  An implantable telemetry platform system for in vivo monitoring of physiological parameters , 2004, IEEE Transactions on Information Technology in Biomedicine.

[5]  Yunghsiang Sam Han,et al.  Power-Efficient Direct-Voting Assurance for Data Fusion in Wireless Sensor Networks , 2008, IEEE Transactions on Computers.

[6]  S. Tahara,et al.  Direct potentiometric determination of chloride ion in whole blood. , 1981, Analytical chemistry.

[7]  Tai-Ping Sun,et al.  All-Solid-State Separated Potassium Electrode Based on SnO2/ITO Glass , 2007 .

[8]  Lei Wang,et al.  Implementation of multichannel sensors for remote biomedical measurements in a microsystems format , 2004, IEEE Transactions on Biomedical Engineering.

[9]  K. G. Ong,et al.  A wireless pH sensor based on the use of salt-independent micro-scale polymer spheres , 2003 .

[10]  Yuan-Hsiang Lin,et al.  A wireless PDA-based physiological monitoring system for patient transport , 2004, IEEE Transactions on Information Technology in Biomedicine.

[11]  P. Pehrsson,et al.  Work function changes and surface chemistry of oxygen, hydrogen, and carbon on indium tin oxide , 2001 .

[12]  Lutz Mädler,et al.  Fundamental studies on SnO2 by means of simultaneous work function change and conduction measurements , 2005 .

[13]  Marios S. Pattichis,et al.  Wireless telemedicine systems: an overview , 2002 .

[14]  Eric Bakker,et al.  Electrochemical sensors. , 2002, Analytical chemistry.

[15]  Mikael Gidlund,et al.  Wireless sensor network based E-health system: Implementation and experimental results , 2010, IEEE Transactions on Consumer Electronics.

[16]  P. Edith Linda,et al.  Network Lifetime Maximization for Estimation in Multihop Wireless Sensor Networks , 2014 .

[17]  M. Mohammadhosseini,et al.  Solid Phase Extraction and Determination of Trace Amounts of Lead(II) using Octadecyl Membrane Disks Modified by a New Schiff's Base and Flame Atomic Absorption Spectrometry , 2006 .

[18]  David C. Yen,et al.  Bluetooth technology: an exploratory study of the analysis and implementation frameworks , 2004, Comput. Stand. Interfaces.

[19]  Y. Umezawa,et al.  Selectivity coefficients for ion-selective electrodes: Recommended methods for reporting KA,Bpot values (Technical Report) , 1995 .

[20]  S. A. M. Makki,et al.  Mobile and wireless Internet access , 2003, Comput. Commun..

[21]  Wen-Yaw Chung,et al.  Study of indium tin oxide thin film for separative extended gate ISFET , 2001 .

[22]  Nikos Vogiatzis,et al.  A review on wireless home network technologies , 2003, MOCO.

[23]  Patrick Boissy,et al.  A smart sensor based on rules and its evaluation in daily routines , 2003, Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439).

[24]  K. Wise,et al.  A wireless microsystem for the remote sensing of pressure, temperature, and relative humidity , 2005, Journal of Microelectromechanical Systems.

[25]  Yanqiu Li,et al.  Hybrid Micropower Source for Wireless Sensor Network , 2008, IEEE Sensors Journal.

[26]  Wen-Yaw Chung,et al.  Study on extended gate field effect transistor with tin oxide sensing membrane , 2000 .

[27]  Study on All-Solid-State Chloride Sensor Based on Tin Oxide/Indium Tin Oxide Glass , 2011 .

[28]  Vivek Tiwari,et al.  Lacas: learning automata-based congestion avoidance scheme for healthcare wireless sensor networks , 2009, IEEE Journal on Selected Areas in Communications.

[29]  David R. S. Cumming,et al.  A system-on-chip digital pH meter for use in a wireless diagnostic capsule , 2005, IEEE Transactions on Biomedical Engineering.

[30]  JAMAL N. AL-KARAKI,et al.  Routing techniques in wireless sensor networks: a survey , 2004, IEEE Wireless Communications.

[31]  JeongGil Ko,et al.  Wireless Sensor Networks for Healthcare , 2010, Proceedings of the IEEE.

[32]  Nikolaos G. Bourbakis,et al.  A Survey on Wearable Sensor-Based Systems for Health Monitoring and Prognosis , 2010, IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews).

[33]  Wen-Yaw Chung,et al.  Separate structure extended gate H+-ion sensitive field effect transistor on a glass substrate , 2000 .

[34]  Robert Koncki,et al.  Recent developments in potentiometric biosensors for biomedical analysis. , 2007, Analytica chimica acta.

[35]  Wan-Young Chung,et al.  Remote monitoring system with wireless sensors module for room environment , 2006 .

[36]  A. Salimi,et al.  Triiodide Ion-Selective Electrode Based on Charge-Transfer Complex of 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo-(8.8.8)hexacosane , 2006 .

[37]  Tai-Ping Sun,et al.  Study on separative structure of EnFET to detect acetylcholine , 2000 .

[38]  María Soledad Belluzo,et al.  Assembling Amperometric Biosensors for Clinical Diagnostics , 2008, Sensors.

[39]  Z. Kafafi,et al.  Work function measurements on indium tin oxide films , 2001 .

[40]  Gregory J. Pottie,et al.  Integrated low-power communication system design for wireless sensor networks , 2004, IEEE Communications Magazine.

[41]  P. R. Troyk,et al.  Integrated multichannel wireless biotelemetry system , 2003, Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439).

[42]  Özgür B. Akan,et al.  Wireless passive sensor networks , 2009, IEEE Communications Magazine.

[43]  M. Yaftian,et al.  A Coated Graphite Thorium-Ion Selective Potentiometric Sensor Based on a Calix[4]arene Bearing Phosphoryl Groups , 2006 .

[44]  S. J. Winick The RF medium in the home-the move to spread spectrum , 1991 .

[45]  C. Farrar,et al.  A Mobile Host Approach for Wireless Powering and Interrogation of Structural Health Monitoring Sensor Networks , 2009, IEEE Sensors Journal.