The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance.
暂无分享,去创建一个
M. Mayo | A. Baldwin | M W Mayo | A S Baldwin
[1] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[2] R. Hay,et al. Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα , 1999, Oncogene.
[3] Céline Gélinas,et al. Rel/NF-?B and I?B factors in oncogenesis , 1997 .
[4] E. Zandi,et al. Bridging the Gap: Composition, Regulation, and Physiological Function of the IκB Kinase Complex , 1999, Molecular and Cellular Biology.
[5] D. Cortez,et al. A requirement for NF-κB activation in Bcr–Abl-mediated transformation , 1998 .
[6] J. Rowley,et al. BCL3 rearrangements and t(14;19) in chronic lymphocytic leukemia and other B‐cell malignancies: A molecular and cytogenetic study , 1997, Genes, chromosomes & cancer.
[7] G. Mosialos. The role of Rel/NF-κB proteins in viral oncogenesis and the regulation of viral transcription , 1997 .
[8] S. Ghosh,et al. IκB Kinases: Kinsmen with Different Crafts , 1999, Science.
[9] B. Dörken,et al. Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. , 1997, The Journal of clinical investigation.
[10] Douglas B. Evans,et al. The Nuclear Factor-κB RelA Transcription Factor Is Constitutively Activated in Human Pancreatic Adenocarcinoma Cells , 1999 .
[11] W. Zong,et al. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis , 1999 .
[12] D. Ballard,et al. The Tax Oncoprotein of Human T-cell Leukemia Virus Type 1 Associates with and Persistently Activates IκB Kinases Containing IKKα and IKKβ* , 1998, The Journal of Biological Chemistry.
[13] A. E. Rogers,et al. Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer. , 1997, The Journal of clinical investigation.
[14] C. Y. Wang,et al. Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras. , 1997, Science.
[15] D. Green,et al. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. , 1998, Molecular cell.
[16] Chris Albanese,et al. NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1 , 1999, Molecular and Cellular Biology.
[17] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[18] S. Ghosh,et al. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. , 1998, Molecular cell.
[19] David Baltimore,et al. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB , 1995, Nature.
[20] P. Vernier,et al. The c-Jun-induced transformation process involves complex regulation of tenascin-C expression , 1997, Molecular and cellular biology.
[21] Claus Scheidereit,et al. NF-κB Function in Growth Control: Regulation of Cyclin D1 Expression and G0/G1-to-S-Phase Transition , 1999, Molecular and Cellular Biology.
[22] M. Taketo,et al. Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas. , 1998, Cancer research.
[23] R. DuBois,et al. Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells , 1998, Cell.
[24] A. MacKenzie,et al. The inhibitors of apoptosis (IAPs) and their emerging role in cancer , 1998, Oncogene.
[25] S. Ferrone,et al. Clinical relevance of ICAM-1 expression in primary lesions and serum of patients with malignant melanoma. , 1993, Cancer research.
[26] K. Jeang,et al. Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB , 1999, The Journal of Biological Chemistry.
[27] G. Dong,et al. Expression of a Dominant-Negative Mutant Inhibitor-κBα of Nuclear Factor-κB in Human Head and Neck Squamous Cell Carcinoma Inhibits Survival, Proinflammatory Cytokine Expression, and Tumor Growth in Vivo , 1999 .
[28] Christian Stehlik,et al. Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis , 1998, The Journal of experimental medicine.
[29] S. Yamaoka,et al. Constitutive activation of NF‐kappa B is essential for transformation of rat fibroblasts by the human T‐cell leukemia virus type I Tax protein. , 1996, The EMBO journal.
[30] A. Neri,et al. Constitutive expression of lymphoma-associated NFKB-2/Lyt-10 proteins is tumorigenic in murine fibroblasts , 1997, Oncogene.
[31] D. Carrasco,et al. Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2 , 1997, The Journal of experimental medicine.
[32] F. Shanahan,et al. Expression of Fas (CD95/APO-1) Ligand by Human Breast Cancers: Significance for Tumor Immune Privilege , 1999, Clinical Diagnostic Laboratory Immunology.
[33] C. Van Waes,et al. The host environment promotes the constitutive activation of nuclear factor-kappaB and proinflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma. , 1999, Cancer research.
[34] L. Ährlund‐Richter,et al. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. , 1999, Cancer research.
[35] R. Gaynor,et al. HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation , 1998, Cell.
[36] L. Cro,et al. Structural alterations of the NF-kappa B transcription factor lyt-10 in lymphoid malignancies. , 1993, Oncogene.
[37] R. Gaynor,et al. The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β , 1998, Nature.
[38] Seamus J. Martin,et al. Suppression of TNF-α-Induced Apoptosis by NF-κB , 1996, Science.
[39] M J May,et al. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.
[40] G. Kollias,et al. Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis , 1999, Nature Medicine.
[41] H. Ohno,et al. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control , 1990, Cell.
[42] R. Gaynor,et al. Sulindac Inhibits Activation of the NF-κB Pathway* , 1999, The Journal of Biological Chemistry.
[43] N. Perkins,et al. Transcriptional Cross Talk between NF-κB and p53 , 1999, Molecular and Cellular Biology.
[44] E. Masini,et al. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. , 1998, Journal of the National Cancer Institute.
[45] Z. Ao,et al. IEX-1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival , 1998 .
[46] N. Colburn,et al. Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes , 1998, Oncogene.
[47] A. Baldwin,et al. THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .
[48] R. Chaganti,et al. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50 , 1991, Cell.
[49] C. Hauser,et al. Oncogenic Neu/ErbB-2 Increases Ets, AP-1, and NF-B-dependent Gene Expression, and Inhibiting Ets Activation Blocks Neu-mediated Cellular Transformation (*) , 1996, The Journal of Biological Chemistry.
[50] Hiroki Sato,et al. Matrix Metalloproteinase 9 Expression Is Induced by Epstein-Barr Virus Latent Membrane Protein 1 C-Terminal Activation Regions 1 and 2 , 1999, Journal of Virology.
[51] D. White,et al. Rel/NF-kappaB/IkappaB proteins and cancer. , 1996, Oncogene.
[52] A. Baldwin,et al. Oncogenic Ras Enhances NF-κB Transcriptional Activity through Raf-dependent and Raf-independent Mitogen-activated Protein Kinase Signaling Pathways* , 1999, The Journal of Biological Chemistry.
[53] Marty W. Mayo,et al. NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis , 1999, Molecular and Cellular Biology.
[54] D. Brenner,et al. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. , 1999, Journal of immunology.
[55] S. Gerondakis,et al. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. , 1999, Genes & development.
[56] J Downward,et al. Ras signalling and apoptosis. , 1998, Current opinion in genetics & development.
[57] E. Zandi,et al. NF-κB-inducing Kinase and IκB Kinase Participate in Human T-cell Leukemia Virus I Tax-mediated NF-κB Activation* , 1998, The Journal of Biological Chemistry.
[58] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[59] J. Tschopp,et al. Oncogenic Ras inhibits Fas ligand‐mediated apoptosis by downregulating the expression of Fas , 1999, The EMBO journal.
[60] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[61] S. Ghosh,et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. , 1994, Science.
[62] J. Romashkova,et al. NF-κB is a target of AKT in anti-apoptotic PDGF signalling , 1999, Nature.
[63] J. Troppmair,et al. Activation of NF-κB by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade , 1998, Oncogene.
[64] Jen-kun Lin,et al. Suppression of TNFα‐mediated NFκb activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells , 1999 .
[65] M. Merville,et al. Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs. , 1999, Cancer research.
[66] A. Baldwin,et al. Activation of Nuclear Factor-κB-dependent Transcription by Tumor Necrosis Factor-α Is Mediated through Phosphorylation of RelA/p65 on Serine 529* , 1998, The Journal of Biological Chemistry.
[67] D. Green,et al. Regulation of Fas-Ligand Expression during Activation-induced Cell Death in T Lymphocytes via Nuclear Factor κB* , 1999, The Journal of Biological Chemistry.
[68] N. Colburn,et al. Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. , 1997, Cancer research.
[69] L. Pfeffer,et al. NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase , 1999, Nature.
[70] J. Cusack,et al. NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B. , 1999, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[71] C. Der,et al. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K , 1997, Nature.
[72] M. Arsura,et al. TGFβ1 Inhibits NF-κB/Rel Activity Inducing Apoptosis of B Cells: Transcriptional Activation of IκBα , 1996 .
[73] W. Greene,et al. Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases , 1998, Molecular and Cellular Biology.
[74] T. Maniatis. Catalysis by a Multiprotein IκB Kinase Complex , 1997, Science.
[75] N. Shimizu,et al. Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression. , 1999, Human gene therapy.
[76] C. Der,et al. Oncogenic Ha-Ras-induced Signaling Activates NF-κB Transcriptional Activity, Which Is Required for Cellular Transformation* , 1997, The Journal of Biological Chemistry.