Excitatory and inhibitory receptive fields of tectal cells are differentially modified by magnocellular and parvocellular divisions of the pigeon nucleus isthmi

Abstract It has been known that magnocellular and parvocellular divisions of the pigeon nucleus isthmi exert excitatory and inhibitory actions on tectal cells, respectively. The present study shows that injection of N-methyl-D-aspartate into the parvocellular division results in an increase in responsive strength and extent of the inhibitory receptive fields, which expand into the excitatory receptive fields of tectal cells. This injection concurrently leads to a decrease in responsiveness and extent of the excitatory fields. On the other hand, injection of acetylcholine into the magnocellular division enhances visual responsiveness, although the excitatory field is not obviously changed in extent. Meanwhile, strength and extent of the inhibitory fields are decreased by acetylcholine. The excitatory and inhibitory fields are reduced in both strength and extent by magnocellular and parvocellular injection of lidocaine, respectively. It suggests that isthmic inputs from both parvocellular and magnocellular divisions converge onto the same tectal cells, and the magnocellular and parvocellular subnuclei can modulate excitatory and inhibitory receptive fields of tectal cells, respectively, with some interactions between both fields.

[1]  Shurong Wang,et al.  Visual responses of neurons in the avian nucleus isthmi , 1986, Neuroscience Letters.

[2]  S. Nakamura,et al.  Long-range competition among the neurons projecting centrifugally to the quail retina , 1998, Visual Neuroscience.

[3]  T. Tömböl.  Golgi and Electron-Microscopic Golgi-GABA Immunostaining Study of the Avian Optic Tectum , 1998, Cells Tissues Organs.

[4]  S. Hunt,et al.  Observations on the projections and intrinsic organization of the pigeon optic tectum: An autoradiographic study based on anterograde and retrograde, axonal and dendritic flow , 1976, The Journal of comparative neurology.

[5]  H. Karten,et al.  Distribution, laminar location, and morphology of tectal neurons projecting to the isthmo‐optic nucleus and the nucleus isthmi, pars parvocellularis in the pigeon (Columba livia) and chick (Gallus domesticus): A retrograde labelling study , 1991, The Journal of comparative neurology.

[6]  J. T. Erichsen,et al.  Distribution of neuropeptide Y, substance P, and Choline acetyltransferase in the developing visual system of the pigeon and effects of unilateral retina removal , 1992, The Journal of comparative neurology.

[7]  J. K. Harting,et al.  Ultrastructural studies of retinal, visual cortical (area 17), and parabigeminal terminals within the superior colliculus of Galago crassicaudatus , 1992, The Journal of comparative neurology.

[8]  S. J. Phillips,et al.  Head orientation in pigeons: postural, locomotor and visual determinants. , 1989, Brain, behavior and evolution.

[9]  Q. Xiao,et al.  Centrifugal innervation modulates visual activity of tectal cells in pigeons , 1998, Visual Neuroscience.

[10]  W. Crossland,et al.  GABA‐like immunoreactivity of neurons in the chicken diencephalon and mesencephalon , 1989, The Journal of comparative neurology.

[11]  H. Karten,et al.  A stereotaxic atlas of the brain of the pigeon (Columba livia) , 1967 .

[12]  T. Tömböl,et al.  Some data on connections of neurons of nuclei isthmi of the chicken. , 1995, Journal fur Hirnforschung.

[13]  H. Karten,et al.  Synaptic interrelationships between the optic tectum and the ipsilateral nucleus isthmi in Rana pipiens , 1994, The Journal of comparative neurology.

[14]  Localization of directionally selective and movement sensitive cells in the optic tectum of the pigeon , 1975, Vision Research.

[15]  A. Pearlman,et al.  Single unit receptive fields and the cellular layers of the pigeon optic tectum. , 1974, Brain research.

[16]  B. Frost,et al.  Excitatory and inhibitory neurotransmitters in the nucleus rotundus of pigeons , 1995, Visual Neuroscience.

[17]  T. Tömböl,et al.  GABA-immunohistological observations, at the electron-microscopical level, of the neurons of isthmic nuclei in chicken, Gallus domesticus , 1998, Cell and Tissue Research.

[18]  Shurong Wang,et al.  GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway , 1994, Neuroscience Letters.

[19]  F. Magni,et al.  Interaction of optic tract and visual wulst impulses on single units of the pigeon's optic tectum. , 1979, Brain, behavior and evolution.

[20]  D. Jassik-Gerschenfeld,et al.  Visual receptive fields of single cells in the pigeon's optic tectum. , 1972, Brain research.

[21]  D. Felix,et al.  Avian Imc-tectal projection is mediated by acetylcholine and glutamate. , 1995, Neuroreport.

[22]  W. Wiggers.  Isthmotectal connections in plethodontid salamanders , 1998, The Journal of comparative neurology.

[23]  V. Chiappinelli,et al.  Immunohistochemical localization of choline acetyltransferase in the chicken mesencephalon , 1989, The Journal of comparative neurology.

[24]  D. Felix,et al.  Effect of acetylcholine and NMDA on neurones of avian tectum and nucleus isthmi. , 1994, Neuroreport.

[25]  D. Jassik-Gerschenfeld,et al.  Single-neuron responses to moving sine-wave gratings in the pigeon optic tectum , 1979, Vision Research.

[26]  A. Reiner,et al.  The distribution of GABA‐containing perikarya, fibers, and terminals in the forebrain and midbrain of pigeons, with particular reference to the basal ganglia and its projection targets , 1994, The Journal of comparative neurology.

[27]  H. Karten,et al.  Laminar distribution of the cells of origin of the descending tectofugal pathways in the pigeon (Columba livia) , 1982, The Journal of comparative neurology.

[28]  Hongfeng Gao,et al.  Receptive field properties of visual neurons in the avian nucleus lentiformis mesencephali , 1998, Experimental Brain Research.

[29]  H. Fibiger,et al.  Acetylcholinesterase and the cholinergic neuron. , 1979, Life sciences.

[30]  B. Frost,et al.  Motion processing in pigeon tectum: equiluminant chromatic mechanisms , 1997, Experimental Brain Research.