Macular Branch Retinal Vein Occlusion: A Revisit and Case Report

Macular branch retinal vein occlusion (BRVO), a type of retinal vein occlusion, is rarely recognised as a distinct entity. Macular BRVO has unique clinical features and different natural courses than the major BRVO. We report a case of a young patient with macular BRVO with macular oedema who was successfully treated with intravitreal ranibizumab injection. A 43 year-old Chinese man with no underlying medical illness presented with 2 weeks history of left eye painless reduced central vision which was worsening over time. On examination, his left eye visual acuity was 6/30 and Amsler chart drawing showed a lower central scotoma. Dilated fundus examination found marked flame-shaped retinal hemorrhages with cotton wool spot over the superior macular area bounded superiorly by superior arcade and macular thickening. An optical coherence tomography revealed cystoid macular oedema; and fundus fluorescein angiography showed occlusion of a small venous branch draining a superior part of macula to superior temporal venous arcade. A complete medical investigation found that he has hypertriglyceridemia and he was managed accordingly. His vision had improved to 6/6 after receiving 3 injections of intravitreal ranibizumab with no residual central scotoma and complete resolution of macular oedema.

[1]  J. o,et al.  Branch retinal vein occlusion sheathotomy , 2019, Vitreoretinal Surgical Techniques.

[2]  K. Tsaousis,et al.  Real-World Results of Switching Treatment from Ranibizumab to Aflibercept in Macular Oedema Secondary to Branch Retinal Vein Occlusion , 2018, Ophthalmology and Therapy.

[3]  M. Elçioğlu,et al.  Comparison of one and three initial monthly intravitreal ranibizumab injection in patients with macular edema secondary to branch retinal vein occlusion. , 2018, International journal of ophthalmology.

[4]  Ying-Cheng Shen,et al.  Risk of Ischemic Stroke, Hemorrhagic Stroke, and All-Cause Mortality in Retinal Vein Occlusion: A Nationwide Population-Based Cohort Study , 2018, Journal of ophthalmology.

[5]  N. Feltgen,et al.  Branch Retinal Vein Occlusion, Macular Ischemia, and Intravitreal Anti-VEGF Therapy , 2017, Case Reports in Ophthalmology.

[6]  A. Orlin,et al.  Clinical Ophthalmology Dovepress Retinal Reperfusion in Diabetic Retinopathy following Treatment with Anti-vegf Intravitreal Injections , 2022 .

[7]  I. Georgalas,et al.  Clinical Ophthalmology Dovepress Comparative Analysis of the Development of Collateral Vessels in Macular Edema Due to Branch Retinal Vein Occlusion following Grid Laser or Ranibizumab Treatment , 2022 .

[8]  L. Prisant,et al.  Branch Retinal Vein Occlusion , 2003, Journal of clinical hypertension.

[9]  W. Annesley,et al.  Macular branch vein occlusion. , 1980, Ophthalmology.

[10]  S. Hayreh,et al.  Branch retinal vein occlusion: natural history of visual outcome. , 2014, JAMA ophthalmology.

[11]  Giuseppe Ravalico,et al.  Foveal avascular zone in macular branch retinal vein occlusion , 2004, International Ophthalmology.