Safety of VYC-12 as a Combination Treatment for Skin Rejuvenation: A Retrospective Analysis of 1577 Treatments

tongue (Figure 1A), which she tolerated well. Two months later, the patient presented with complete response to treated test spot (Figure 1B) without evidence of scarring or atrophy. She then opted for treatment of the remaining pigmentation and underwent treatment with 694-nmQSRLwith settings of 4 J/cm, 4-mm spot size until appropriate endpoint of gray/white change was appreciated. Again, the patient tolerated the procedure well. A dramatic response was noted just 4 days postprocedure, with complete clearance of pigmentation (Figure 1C) and restoration to natural mucosal color. There was no evidence of edema or erythema, and no recurrence was found at 2-month follow-up.

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