Detection of posterior vortex veins in eyes with pathologic myopia by ultra-widefield indocyanine green angiography

Aims To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). Methods One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. Results Posterior vortex veins were found in 80 eyes (26%). The prevalence of posterior staphyloma was significantly higher in eyes in which posterior vortex vein was detected than in eyes without posterior vortex vein. The posterior vortex veins were classified into five types according to the site of exit from the eye; around the optic nerve in 28%, in the macular area in 17%, along the border of staphyloma in 6%, along the margin of macular atrophy or large peripapillary conus in 21%, and elsewhere in 28%. In one eye, two posterior vortex veins collected the choroidal venous blood from the entire fundus. Conclusions Wide-field ICGA can analyse the characteristic features of choroidal blood outflow system through posterior vortex veins in highly myopic eyes. They may play an important role as routes of choroidal outflow in highly myopic eyes.

[1]  T. Lai,et al.  Updates of pathologic myopia , 2016, Progress in Retinal and Eye Research.

[2]  K. Xue,et al.  Heidelberg Spectralis ultra-widefield fundus fluorescein angiography in infants. , 2016, American journal of ophthalmology.

[3]  S. Srinivas,et al.  FEASIBILITY AND CLINICAL UTILITY OF ULTRA-WIDEFIELD INDOCYANINE GREEN ANGIOGRAPHY , 2014, Retina.

[4]  Szilárd Kiss,et al.  Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis® noncontact ultra-widefield module versus the Optos® Optomap® , 2013, Clinical ophthalmology.

[5]  M. Akiba,et al.  Observations of vascular structures within and posterior to sclera in eyes with pathologic myopia by swept-source optical coherence tomography. , 2012, Investigative ophthalmology & visual science.

[6]  M. Mochizuki,et al.  Morphology and long-term changes of choroidal vascular structure in highly myopic eyes with and without posterior staphyloma. , 2007, Ophthalmology.

[7]  Ayyakkannu Manivannan,et al.  Ultra-wide-field fluorescein angiography of the ocular fundus. , 2005, American journal of ophthalmology.

[8]  T. Amemiya,et al.  Microvascular architecture of the rat choroid: Corrosion cast study , 2001, The Anatomical record.

[9]  T. Amemiya,et al.  Corrosion cast demonstration of choroidal vasculature in normal Wistar Kyoto rat. , 2001, Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia.

[10]  Y. Kitazawa,et al.  Optic nerve and peripapillary choroidal microvasculature of the rat eye. , 1999, Investigative ophthalmology & visual science.

[11]  J. Slakter,et al.  WIDE‐ANGLE INDOCYANINE GREEN ANGIOGRAPHY , 1998, Retina.

[12]  K. Ohno-Matsui,et al.  The long-term follow-up of a highly myopic patient with a macular vortex vein. , 2009, Acta ophthalmologica Scandinavica.

[13]  G. Ruskell Peripapillary venous drainage from the choroid: a variable feature in human eyes , 1997, The British journal of ophthalmology.

[14]  S. Kishi,et al.  Watershed zone in the human peripheral choroid. , 1996, Ophthalmology.

[15]  K. Ohno-Matsui,et al.  POSTERIOR ROUTES OF CHOROIDAL BLOOD OUTFLOW IN HIGH MYOPIA , 1996, Retina.

[16]  S. Hayasaka,et al.  Vortex veins in the macula. , 1988, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde.

[17]  H. Yoshimoto,et al.  Studies on the angioarchitecture of the posterior choroid in rat and role of posterior ciliary vein. , 1980, Investigative ophthalmology & visual science.

[18]  D. Carpenter,et al.  Choroidal blood flow as a heat dissipating mechanism in the macula. , 1980, American journal of ophthalmology.

[19]  P. Lichter,et al.  Posterior vortex vein and congenital glaucoma in a patient with trisomy 13 syndrome. , 1975, American journal of ophthalmology.

[20]  D. Worthen,et al.  Histology of the Human Eye. , 1972 .