Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8mh00727f
暂无分享,去创建一个
Daniel E. Mitchell | Muhammad Hasan | M. Gibson | J. Gutierrez-Marcos | Alice E R Fayter | R. C. Deller
[1] M. Gibson,et al. Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Microorganisms , 2018, Biomacromolecules.
[2] Mark W. Tibbitt,et al. Thermal Stabilization of Biologics with Photoresponsive Hydrogels. , 2018, Biomacromolecules.
[3] H. V. van Leeuwen,et al. Dietary trehalose enhances virulence of epidemic Clostridium difficile , 2017, Nature.
[4] Ranjita Shegokar,et al. Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications , 2016, Expert opinion on drug delivery.
[5] Daniel E. Mitchell,et al. Combining Biomimetic Block Copolymer Worms with an Ice‐Inhibiting Polymer for the Solvent‐Free Cryopreservation of Red Blood Cells , 2016, Angewandte Chemie.
[6] Daniel E. Mitchell,et al. Gold Nanoparticle Aggregation as a Probe of Antifreeze (Glyco) Protein-Inspired Ice Recrystallization Inhibition and Identification of New IRI Active Macromolecules , 2015, Scientific Reports.
[7] Shaoyi Jiang,et al. Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity , 2015, Proceedings of the National Academy of Sciences.
[8] M. Vatish,et al. Glycerol-Free Cryopreservation of Red Blood Cells Enabled by Ice-Recrystallization-Inhibiting Polymers. , 2015, ACS biomaterials science & engineering.
[9] Wei Wang,et al. Advanced protein formulations , 2015, Protein science : a publication of the Protein Society.
[10] J. Acker,et al. Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations , 2015, Scientific Reports.
[11] B. Nidetzky,et al. Protein freeze concentration and micro-segregation analysed in a temperature-controlled freeze container , 2015, Biotechnology reports.
[12] M. Vatish,et al. Synthetic polymers enable non-vitreous cellular cryopreservation by reducing ice crystal growth during thawing , 2014, Nature Communications.
[13] E. Andreakos,et al. Therapeutic human monoclonal antibodies in inflammatory diseases. , 2014, Methods in molecular biology.
[14] En-Wei Lin,et al. Trehalose glycopolymers as excipients for protein stabilization. , 2013, Biomacromolecules.
[15] R. Notman,et al. Antifreeze (glyco)protein mimetic behavior of poly(vinyl alcohol): detailed structure ice recrystallization inhibition activity study. , 2013, Biomacromolecules.
[16] Diana Gil,et al. Strategies to stabilize compact folding and minimize aggregation of antibody-based fragments , 2013, Advances in bioscience and biotechnology.
[17] Hai Pan,et al. Mechanistic insights into the stabilization of srcSH3 by PEGylation. , 2012, Langmuir : the ACS journal of surfaces and colloids.
[18] H. Maynard,et al. Trehalose glycopolymers for stabilization of protein conjugates to environmental stressors. , 2012, Journal of the American Chemical Society.
[19] J. Wolchok,et al. Antibody therapy of cancer , 2012, Nature Reviews Cancer.
[20] Katherine Kho,et al. A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid-polymer hybrid nanoparticles. , 2012, International journal of pharmaceutics.
[21] R. D. Jangle,et al. Vacuum Foam Drying: An Alternative to Lyophilization for Biomolecule Preservation , 2012, Indian journal of pharmaceutical sciences.
[22] D. Dimitrov. Therapeutic proteins. , 2012, Methods in molecular biology.
[23] R. Ionescu,et al. Fragmentation of monoclonal antibodies , 2011, mAbs.
[24] M. Gibson. Slowing the growth of ice with synthetic macromolecules: beyond antifreeze(glyco) proteins , 2010 .
[25] O. Leavy. Therapeutic antibodies: past, present and future , 2010, Nature Reviews Immunology.
[26] Brian M. Murphy,et al. Stability of Protein Pharmaceuticals: An Update , 2010, Pharmaceutical Research.
[27] C. Rowley,et al. Solution conformation of C-linked antifreeze glycoprotein analogues and modulation of ice recrystallization. , 2009, Journal of the American Chemical Society.
[28] I. Roy,et al. Effect of trehalose on protein structure , 2008, Protein science : a publication of the Protein Society.
[29] C Simone Fishburn,et al. The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics. , 2008, Journal of pharmaceutical sciences.
[30] C. Katagiri,et al. In Situ Observation of Antifreeze Glycoprotein Kinetics at the Ice Interface Reveals a Two-Step Reversible Adsorption Mechanism , 2008 .
[31] Xiao Dong Chen,et al. Glucose oxidase: natural occurrence, function, properties and industrial applications , 2008, Applied Microbiology and Biotechnology.
[32] Michael J. Pikal,et al. Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization , 2007, Pharmaceutical development and technology.
[33] R. Bhat,et al. Why Is Trehalose an Exceptional Protein Stabilizer? , 2003, Journal of Biological Chemistry.
[34] A. Haymet,et al. 'Antifreeze' glycoproteins from polar fish. , 2003, European journal of biochemistry.
[35] C. Demerlis,et al. Review of the oral toxicity of polyvinyl alcohol (PVA). , 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[36] Michael Farnum,et al. Effect of glycerol on the interactions and solubility of bovine pancreatic trypsin inhibitor. , 1999, Biophysical journal.
[37] R L Lundblad,et al. Colorimetric protein assay techniques , 1999, Biotechnology and applied biochemistry.
[38] S J Prestrelski,et al. Separation of freezing- and drying-induced denaturation of lyophilized proteins using stress-specific stabilization. I. Enzyme activity and calorimetric studies. , 1993, Archives of biochemistry and biophysics.
[39] T. N. Hansen,et al. Antifreeze protein modulates cell survival during cryopreservation: mediation through influence on ice crystal growth. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[40] K. Mullis,et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. , 1988, Science.