Optical fiber-based sensors: application to chemical biology.

Optical fibers have been used to develop sensors based on nucleic acids and cells. Sensors employing DNA probes have been developed for various genomics applications and microbial pathogen detection. Live cell-based sensors have enabled the monitoring of environmental toxins, and have been used for fundamental studies on populations of individual cells. Both single-core optical fiber sensors and optical fiber sensor arrays have been used for sensing based on nucleic acids and live cells.

[1]  S. Cosnier,et al.  Optical fiber immunosensor based on a poly(pyrrole-benzophenone) film for the detection of antibodies to viral antigen. , 2005, Analytical chemistry.

[2]  Harbans S. Dhadwal,et al.  Capillary waveguide nucleic acid based biosensor , 2004 .

[3]  D. Stenger,et al.  Biological threat detection via host gene expression profiling. , 2003, Clinical chemistry.

[4]  David R Walt,et al.  Living bacterial cell array for genotoxin monitoring. , 2004, Analytical chemistry.

[5]  David R Walt,et al.  Simultaneously monitoring gene expression kinetics and genetic noise in single cells by optical well arrays. , 2004, Analytical chemistry.

[6]  Sebastian Meier-Ewert,et al.  A three-hybrid approach to scanning the proteome for targets of small molecule kinase inhibitors. , 2004, Chemistry & biology.

[7]  Philippe Rigault,et al.  A novel, high-performance random array platform for quantitative gene expression profiling. , 2004, Genome research.

[8]  Marko Virta,et al.  Detection of bioavailable heavy metals in EILATox‐Oregon samples using whole‐cell luminescent bacterial sensors in suspension or immobilized onto fibre‐optic tips , 2004, Journal of applied toxicology : JAT.

[9]  D Bentley,et al.  Highly parallel SNP genotyping. , 2003, Cold Spring Harbor symposia on quantitative biology.

[10]  Srivatsa Venkatasubbarao,et al.  Microarrays--status and prospects. , 2004, Trends in biotechnology.

[11]  A. MacKenzie,et al.  Rapid detection of single nucleotide polymorphisms associated with spinal muscular atrophy by use of a reusable fibre-optic biosensor. , 2004, Nucleic acids research.

[12]  Monika Milewski,et al.  Decoding randomly ordered DNA arrays. , 2004, Genome research.

[13]  S. Daunert,et al.  Phosphate binding protein as the biorecognition element in a biosensor for phosphate. , 2004, Sensors and actuators. B, Chemical.

[14]  Yechezkel Kashi,et al.  Array-based binary analysis for bacterial typing. , 2005, Analytical chemistry.

[15]  J. Wang-Rodriguez,et al.  Gene expression profiles in formalin-fixed, paraffin-embedded tissues obtained with a novel assay for microarray analysis. , 2004, Clinical chemistry.

[16]  Philip Lijnzaad,et al.  An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas , 2005, Nature Genetics.

[17]  Jian-Bing Fan,et al.  Tumorigenesis and Neoplastic Progression Quantitative Gene Expression Profiling in Formalin-Fixed , Paraffin-Embedded Tissues Using Universal Bead Arrays , 2004 .

[18]  Douglas R Call,et al.  Detection of bacterial pathogens in environmental samples using DNA microarrays. , 2003, Journal of microbiological methods.

[19]  M. Janitz,et al.  High-throughput gene silencing using cell arrays , 2004, Oncogene.

[20]  Masahiro Kudo,et al.  Development of fluorescence change-based, reagent-less optic immunosensor. , 2005, Biosensors & bioelectronics.

[21]  S. Belkin.  Microbial whole-cell sensing systems of environmental pollutants. , 2003, Current opinion in microbiology.

[22]  L. Bodrossy,et al.  Oligonucleotide microarrays in microbial diagnostics. , 2004, Current opinion in microbiology.

[23]  Arun K. Bhunia,et al.  Detection of Low Levels of Listeria monocytogenes Cells by Using a Fiber-Optic Immunosensor , 2004, Applied and Environmental Microbiology.

[24]  K. Gunderson,et al.  High-throughput SNP genotyping on universal bead arrays. , 2005, Mutation research.

[25]  Sophia Tsoka,et al.  Beyond 100 genomes , 2003, Genome Biology.

[26]  K. Balkus,et al.  Optical encoding with shaped DAM-1 molecular sieve particles. , 2003, Lab on a chip.

[27]  Ulrich J. Krull,et al.  A fibre-optic biosensor for detection of microbial contamination , 2003 .

[28]  T. Hirano,et al.  An analysis of changes in the expression of cyclins A and B1 by the cell array system during the cell cycle: Comparison between cell synchronization methods , 2003, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[29]  Li Feng,et al.  Expression profiling using a hexamer-based universal microarray , 2004, Nature Biotechnology.

[30]  Ulrich J Krull,et al.  Synthesis and fluorescence studies of thiazole orange tethered onto oligonucleotide: development of a self-contained DNA biosensor on a fiber optic surface. , 2005, Bioorganic & medicinal chemistry letters.

[31]  Sheila A Grant,et al.  Effects of immobilization on a FRET immunosensor for the detection of myocardial infarction , 2005, Analytical and bioanalytical chemistry.

[32]  P. Prasad,et al.  Detection of trophic factor activated signaling molecules in cells by a compact fiber-optic sensor. , 2004, Biosensors & bioelectronics.

[33]  D. Walt,et al.  High-density, microsphere-based fiber optic DNA microarrays. , 2003, Biosensors & bioelectronics.

[34]  Hiroyuki Fujita,et al.  Microfabricated arrays of femtoliter chambers allow single molecule enzymology , 2005, Nature Biotechnology.

[35]  Eliora Z Ron,et al.  Optical imaging fiber-based live bacterial cell array biosensor. , 2003, Analytical biochemistry.

[36]  K. Gunderson,et al.  A genome-wide scalable SNP genotyping assay using microarray technology , 2005, Nature Genetics.

[37]  David R Walt,et al.  Combinatorial decoding: an approach for universal DNA array fabrication. , 2003, Journal of the American Chemical Society.

[38]  J. Ecker,et al.  Applications of DNA tiling arrays for whole-genome analysis. , 2005, Genomics.

[39]  C. Croce,et al.  An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[40]  D. Walt,et al.  Optical fiber-based biosensors , 2004, Analytical and bioanalytical chemistry.

[41]  Jian-Bing Fan,et al.  A versatile assay for high-throughput gene expression profiling on universal array matrices. , 2004, Genome research.

[42]  D. Walt,et al.  Individual cell migration analysis using fiber-optic bundles , 2005, Analytical and bioanalytical chemistry.