For multi-pulse radiography facilities, we are investigating the possible adverse effects of (1) backstreaming ion emission from the bremsstrahlung converter target and (2) the interaction of the resultant plasma with the electron beam during subsequent pulses. These effects would primarily manifest themselves in a static focusing system as a rapidly varying X-ray spot. To study these effects, we are conducting beam-target interaction experiments on the ETA-II accelerator (a 6.0 MeV, 2.5 kA, 70 ns FWHM pulsed, electron accelerator) by measuring spot dynamics and characterizing the resultant plasma for various configurations.