Gintonin Isolated from Ginseng Inhibits the Epithelial—Mesenchymal Transition Induced by TGF-β in A549 Lung Cancer Cells
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S. Nah | K. Kang | Il-Ho Park | M. Shin | Sung Jin Kim
[1] Chang Liu,et al. Potential Oral Health Benefits of Ginseng and Its Extracts , 2023, International dental journal.
[2] Sun-Hye Choi,et al. Wound Healing Effect of Gintonin Involves Lysophosphatidic Acid Receptor/Vascular Endothelial Growth Factor Signaling Pathway in Keratinocytes , 2021, International journal of molecular sciences.
[3] Sun-Hye Choi,et al. The Gintonin-Enriched Fraction of Ginseng Regulates Lipid Metabolism and Browning via the cAMP-Protein Kinase a Signaling Pathway in Mice White Adipocytes , 2020, Biomolecules.
[4] M. Kim,et al. Ongoing Research on the Role of Gintonin in the Management of Neurodegenerative Disorders , 2020, Cells.
[5] M. Fares,et al. Molecular principles of metastasis: a hallmark of cancer revisited , 2020, Signal Transduction and Targeted Therapy.
[6] M. Schabath,et al. Cancer Progress and Priorities: Lung Cancer , 2019, Cancer Epidemiology, Biomarkers & Prevention.
[7] V. Mittal. Epithelial Mesenchymal Transition in Tumor Metastasis. , 2018, Annual review of pathology.
[8] Sun-Hye Choi,et al. Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly , 2017, Alzheimer disease and associated disorders.
[9] Byung-Hwan Lee,et al. Gintonin attenuates depressive-like behaviors associated with alcohol withdrawal in mice. , 2017, Journal of affective disorders.
[10] Byung-Hwan Lee,et al. Effects of gintonin-enriched fraction on hippocampal cell proliferation in wild-type mice and an APPswe/PSEN-1 double Tg mouse model of Alzheimer's disease , 2016, Neurochemistry International.
[11] C. Zappa,et al. Non-small cell lung cancer: current treatment and future advances. , 2016, Translational lung cancer research.
[12] Byung-Hwan Lee,et al. Gintonin enhances performance of mice in rotarod test: Involvement of lysophosphatidic acid receptors and catecholamine release , 2016, Neuroscience Letters.
[13] K. Kang,et al. Sanguiin H6 suppresses TGF-β induction of the epithelial-mesenchymal transition and inhibits migration and invasion in A549 lung cancer. , 2015, Bioorganic & medicinal chemistry letters.
[14] Hyeonseok Ko. Geraniin inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses A549 lung cancer migration, invasion and anoikis resistance. , 2015, Bioorganic & medicinal chemistry letters.
[15] Sang Myung Lee,et al. Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition , 2015, Journal of ginseng research.
[16] Ho-Chul Shin,et al. Gintonin, a novel ginseng-derived lysophosphatidic acid receptor ligand, stimulates neurotransmitter release , 2015, Neuroscience Letters.
[17] D. Medici,et al. Signaling mechanisms of the epithelial-mesenchymal transition , 2014, Science Signaling.
[18] Samy Lamouille,et al. Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.
[19] Hyung Gyun Kim,et al. Saponins from the Roots of Platycodon grandiflorum Suppresses TGFβ1-Induced Epithelial-Mesenchymal Transition Via Repression of PI3K/Akt, ERK1/2 and Smad2/3 Pathway in Human Lung Carcinoma A549 Cells , 2014, Nutrition and cancer.
[20] S. Nah,et al. Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin , 2013, Acta Pharmacologica Sinica.
[21] Jiyeon Kim,et al. CK2 Inhibitor CX-4945 Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition in A549 Human Lung Adenocarcinoma Cells , 2013, PloS one.
[22] Hyeonseok Ko,et al. TGF-β1-induced epithelial-mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in human A549 lung cancer cells. , 2013, Cancer letters.
[23] W. Travis,et al. New pathologic classification of lung cancer: relevance for clinical practice and clinical trials. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] H. Ford,et al. Molecular Pathways Molecular Pathways : Targeting the TGF-b Pathway for Cancer Therapy , 2012 .
[25] M. Tatari,et al. EMT as the ultimate survival mechanism of cancer cells. , 2012, Seminars in cancer biology.
[26] Ho-Chul Shin,et al. Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity , 2012, Molecules and cells.
[27] Ming-chuan Zhao,et al. Transforming growth factor-β1 promotes lung adenocarcinoma invasion and metastasis by epithelial-to-mesenchymal transition , 2011, Molecular and Cellular Biochemistry.
[28] Byung-Hwan Lee,et al. A Simple Method for the Preparation of Crude Gintonin from Ginseng Root, Stem, and Leaf , 2011, Journal of ginseng research.
[29] Sarah Spiegel,et al. International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature , 2010, Pharmacological Reviews.
[30] R. Huang,et al. Epithelial-Mesenchymal Transitions in Development and Disease , 2009, Cell.
[31] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[32] J. Massagué,et al. TGFβ in Cancer , 2008, Cell.
[33] Héctor Peinado,et al. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? , 2007, Nature Reviews Cancer.
[34] S. Jakowlew. Transforming growth factor-β in cancer and metastasis , 2006, Cancer and Metastasis Reviews.
[35] J. Massagué,et al. The logic of TGFβ signaling , 2006 .
[36] Ying E. Zhang,et al. Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.
[37] W. Fiers,et al. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role , 1991, Cell.
[38] Ho-Chul Shin,et al. Suppression of metastasis of intravenously-inoculated B16/F10 melanoma cells by the novel ginseng-derived ingredient, gintonin: involvement of autotaxin inhibition. , 2013, International journal of oncology.
[39] Hyoung-Chun Kim,et al. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing. , 2012, Journal of Alzheimer's disease : JAD.