Analyzing immune responses to varied mRNA and protein vaccine sequences

[1]  Xiuling Li,et al.  AddaVax-Adjuvanted H5N8 Inactivated Vaccine Induces Robust Humoral Immune Response against Different Clades of H5 Viruses , 2022, Vaccines.

[2]  P. Earl,et al.  Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection , 2022, Proceedings of the National Academy of Sciences of the United States of America.

[3]  F. Baldanti,et al.  Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant , 2022, Nature Communications.

[4]  H. Ansari,et al.  Adverse events following COVID-19 vaccination: A systematic review and meta-analysis , 2022, International Immunopharmacology.

[5]  Michael John Smith,et al.  Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021. , 2022, JAMA.

[6]  E. Dolgin mRNA flu shots move into trials , 2021, Nature Reviews Drug Discovery.

[7]  F. Huang,et al.  To mix or not to mix? A rapid systematic review of heterologous prime–boost covid-19 vaccination , 2021, Expert review of vaccines.

[8]  J. Münch,et al.  Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination , 2021, Nature Medicine.

[9]  Jun Chang,et al.  Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-based adjuvant , 2021, Scientific Reports.

[10]  R. Compans,et al.  Intranasal vaccination with influenza HA/GO-PEI nanoparticles provides immune protection against homo- and heterologous strains , 2021, Proceedings of the National Academy of Sciences.

[11]  Lisa E. Gralinski,et al.  Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 , 2020, Cell.

[12]  Hyo‐Jung Park,et al.  Inactivated influenza vaccine formulated with single-stranded RNA-based adjuvant confers mucosal immunity and cross-protection against influenza virus infection. , 2020, Vaccine.

[13]  Yu Chen,et al.  Galectin-1 Ameliorates Influenza A H1N1pdm09 Virus-Induced Acute Lung Injury , 2020, Frontiers in Microbiology.

[14]  S. Gurunathan,et al.  The promise of mRNA vaccines: a biotech and industrial perspective , 2020, npj Vaccines.

[15]  Michael R Hamblin,et al.  Comparison of DNA and mRNA vaccines against cancer. , 2019, Drug discovery today.

[16]  C. Lacroix,et al.  Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response. , 2019, Trends in molecular medicine.

[17]  Steven L Salzberg,et al.  Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype , 2019, Nature Biotechnology.

[18]  J. Puetz,et al.  Recombinant Proteins for Industrial versus Pharmaceutical Purposes: A Review of Process and Pricing , 2019, Processes.

[19]  U. Şahin,et al.  A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA , 2019, Molecular therapy. Nucleic acids.

[20]  L. Rudenko,et al.  Basics of CD8 T-cell immune responses after influenza infection and vaccination with inactivated or live attenuated influenza vaccine , 2018, Expert review of vaccines.

[21]  D. Hawksworth Advancing Freund's and AddaVax Adjuvant Regimens Using CpG Oligodeoxynucleotides. , 2018, Monoclonal antibodies in immunodiagnosis and immunotherapy.

[22]  K. Richards,et al.  CD4 T cells in protection from influenza virus: Viral antigen specificity and functional potential , 2018, Immunological reviews.

[23]  K. Kang,et al.  Heterologous prime–boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus , 2018, Vaccine.

[24]  S. Varga,et al.  The CD8 T Cell Response to Respiratory Virus Infections , 2018, Front. Immunol..

[25]  Marla Shapiro,et al.  Understanding modern-day vaccines: what you need to know , 2018, Annals of medicine.

[26]  D. Weissman,et al.  mRNA vaccines — a new era in vaccinology , 2018, Nature Reviews Drug Discovery.

[27]  S. Choi,et al.  Bathing effects of east saline groundwater concentrates on allergic (atopic) dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in hairless mice , 2017, Experimental and therapeutic medicine.

[28]  P. Thomas,et al.  Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection , 2016, Front. Immunol..

[29]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[30]  S. Joshi,et al.  Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies. , 2014, Biologicals : journal of the International Association of Biological Standardization.

[31]  Björn Usadel,et al.  Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..

[32]  Wei Shi,et al.  featureCounts: an efficient general purpose program for assigning sequence reads to genomic features , 2013, Bioinform..

[33]  Bernhard Mlecnik,et al.  CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data , 2013, Bioinform..

[34]  Nathan M Belliveau,et al.  Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA , 2012, Molecular therapy. Nucleic acids.

[35]  J. Taubenberger,et al.  Influenza virus evolution, host adaptation, and pandemic formation. , 2010, Cell host & microbe.

[36]  Davis J. McCarthy,et al.  edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..

[37]  Pornpimol Charoentong,et al.  ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks , 2009, Bioinform..

[38]  Istvan Toth,et al.  Self-adjuvanting lipopeptide vaccines. , 2008, Current medicinal chemistry.

[39]  Houping Ni,et al.  Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. , 2005, Immunity.

[40]  P. Shannon,et al.  Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks , 2003 .

[41]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[42]  G. Acsadi,et al.  Direct gene transfer into mouse muscle in vivo. , 1990, Science.

[43]  Stefaan C De Smedt,et al.  Evading innate immunity in nonviral mRNA delivery: don't shoot the messenger. , 2016, Drug discovery today.