Radiation induces diffusible feeder cell factor(s) that cooperate with ROCK inhibitor to conditionally reprogram and immortalize epithelial cells.

[1]  S. Randell,et al.  Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells , 2012, Proceedings of the National Academy of Sciences.

[2]  Chris Albanese,et al.  ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells. , 2012, The American journal of pathology.

[3]  A. Jimeno,et al.  Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy , 2011, Nature Medicine.

[4]  Craig Meyers,et al.  Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor. , 2010, The Journal of clinical investigation.

[5]  Fang Li,et al.  Apoptotic Cells Activate the “Phoenix Rising” Pathway to Promote Wound Healing and Tissue Regeneration , 2010, Science Signaling.

[6]  M. Denning,et al.  Role for protein kinase C-alpha in keratinocyte growth arrest. , 2009, The Journal of investigative dermatology.

[7]  J. Martinou,et al.  Apoptotic cells provide an unexpected source of Wnt3 signaling to drive hydra head regeneration. , 2009, Developmental cell.

[8]  R. Schlegel,et al.  HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function. , 2008, Virology.

[9]  A. Kimchi,et al.  The death-associated protein kinases: structure, function, and beyond. , 2006, Annual review of biochemistry.

[10]  J. Segre,et al.  Epidermal barrier formation and recovery in skin disorders. , 2006, The Journal of clinical investigation.

[11]  Jian Wang,et al.  Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. , 2006, Genes & development.

[12]  J. Feijen,et al.  Induction of apoptosis by heat and γ-radiation in a human lymphoid cell line; role of mitochondrial changes and caspase activation , 2006, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[13]  Jun R Huh,et al.  Compensatory Proliferation Induced by Cell Death in the Drosophila Wing Disc Requires Activity of the Apical Cell Death Caspase Dronc in a Nonapoptotic Role , 2004, Current Biology.

[14]  T. Gojobori,et al.  Detection of apoptosis during planarian regeneration by the expression of apoptosis-related genes and TUNEL assay. , 2004, Gene.

[15]  Baojin Fu,et al.  Keratinocyte growth conditions modulate telomerase expression, senescence, and immortalization by human papillomavirus type 16 E6 and E7 oncogenes. , 2003, Cancer research.

[16]  Larry Kedes,et al.  HES and HERP families: Multiple effectors of the notch signaling pathway , 2003, Journal of cellular physiology.

[17]  W. Hahn,et al.  A Two-Stage, p16INK4A- and p53-Dependent Keratinocyte Senescence Mechanism That Limits Replicative Potential Independent of Telomere Status , 2002, Molecular and Cellular Biology.

[18]  S. Werner,et al.  The Mad1 transcription factor is a novel target of activin and TGF-β action in keratinocytes: possible role of Mad1 in wound repair and psoriasis , 2001, Oncogene.

[19]  Freddy Radtke,et al.  Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation , 2001, The EMBO journal.

[20]  R. Cancedda,et al.  Treatment of "stable" vitiligo by Timedsurgery and transplantation of cultured epidermal autografts. , 2000, Archives of dermatology.

[21]  G. Pellegrini,et al.  The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. , 1999, Transplantation.

[22]  J. Christopher Grimaldi,et al.  Introduction to Cell and Tissue Culture: Theory And Technique , 1998 .

[23]  M. Ponec,et al.  Normalization of epidermal calcium distribution profile in reconstructed human epidermis is related to improvement of terminal differentiation and stratum corneum barrier formation. , 1998, The Journal of investigative dermatology.

[24]  F. Bonte,et al.  Expression of Bcl‐2 and Bax in cultured normal human keratinocytes and melanocytes: relationship to differentiation and melanogenesis , 1997, The British journal of dermatology.

[25]  S. Werner,et al.  Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skin. , 1996, British Journal of Cancer.

[26]  P. Steinert,et al.  The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell Envelope (*) , 1995, The Journal of Biological Chemistry.

[27]  W. Hickerson,et al.  Acceleration of skin regeneration from cultured epithelial autografts by transplantation to homograft dermis. , 1993, The Journal of burn care & rehabilitation.

[28]  S. Murthy,et al.  Tissue-specific and differentiation-appropriate expression of the human involucrin gene in transgenic mice: an abnormal epidermal phenotype. , 1993, Differentiation; research in biological diversity.

[29]  B. Gilchrest,et al.  Modulation of mRNA levels during human keratinocyte differentiation , 1992, Journal of cellular physiology.

[30]  D. Scudiero,et al.  New colorimetric cytotoxicity assay for anticancer-drug screening. , 1990, Journal of the National Cancer Institute.

[31]  R. Schlegel,et al.  Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma. , 1988, The EMBO journal.

[32]  P. Elias,et al.  Biochemical and morphological characterization of growth and differentiation of normal human neonatal keratinocytes in a serum‐free medium , 1988, Journal of cellular physiology.

[33]  Joseph McGuire,et al.  USE OF CULTURED EPIDERMAL AUTOGRAFTS AND DERMAL ALLOGRAFTS AS SKIN REPLACEMENT AFTER BURN INJURY , 1986, The Lancet.

[34]  P. Elias,et al.  Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization by ion-capture cytochemistry. , 1985, The Journal of investigative dermatology.

[35]  R. Rice,et al.  Modulation of involucrin and envelope competence in human keratinocytes by hydrocortisone, retinyl acetate, and growth arrest. , 1983, Cancer research.

[36]  Karen Holbrook,et al.  Calcium regulation of growth and differentiation of mouse epidermal cells in culture , 1980, Cell.

[37]  H. Green,et al.  Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is , 1975, Cell.

[38]  C. Mothersill,et al.  Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect. , 2013, Mutation research.

[39]  M. Levin,et al.  Apoptosis is required during early stages of tail regeneration in Xenopus laevis. , 2007, Developmental biology.

[40]  Gustavo Droguett,et al.  DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation , 2000, Nature Cell Biology.

[41]  C. Compton,et al.  Cultured epidermal autografts and allodermis combination for permanent burn wound coverage. , 1994, Burns : journal of the International Society for Burn Injuries.

[42]  K. Hesse.  Phoenix Rising , 1994 .

[43]  H Green,et al.  Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. , 1975, Cell.