The in vitro micronucleus technique.
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[1] S. Carter. Effects of Cytochalasins on Mammalian Cells , 1967, Nature.
[2] J A Heddle,et al. A rapid in vivo test for chromosomal damage. , 1973, Mutation research.
[3] W Schmid,et al. The micronucleus test. , 1975, Mutation research.
[4] E. Tan,et al. Distribution of kinetochore (centromere) antigen in mammalian cell nuclei , 1981, The Journal of cell biology.
[5] W. Straus. Imidazole increases the sensitivity of the cytochemical reaction for peroxidase with diaminobenzidine at a neutral pH. , 1982, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[6] A. Natarajan,et al. Chapter 7 – Mutagenicity Testing with Cultured Mammalian Cells: Cytogenetic Assays , 1982 .
[7] R. Tice,et al. Aneuploidy and health risk assessment: current status and future directions. , 1985, Environmental mutagenesis.
[8] M. Fenech,et al. Measurement of micronuclei in lymphocytes. , 1985, Mutation research.
[9] M. Fenech,et al. Solutions to the kinetic problem in the micronucleus assay. , 1985, Cytobios.
[10] M. Fenech,et al. Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation. , 1986, Mutation research.
[11] B. Vig,et al. Sequence of centromere separation: kinetochore formation in induced laggards and micronuclei. , 1986, Mutagenesis.
[12] A. Wakata,et al. Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: comparison with types and rates of chromosome aberrations. , 1987, Mutation research.
[13] C. Tanzarella,et al. Immunofluorescent staining of kinetochores in micronuclei: a new assay for the detection of aneuploidy. , 1988, Mutation research.
[14] D. Lloyd,et al. RADIATION INDUCTION OF MICRONUCLEI IN HUMAN LYMPHOCYTES , 1988 .
[15] P. Perry,et al. The identification of micronucleated chromosomes: a possible assay for aneuploidy. , 1988, Mutagenesis.
[16] J D Tucker,et al. Identification of aneuploidy‐inducing agents using cytokinesis‐blocked human lymphocytes and an antikinetochore antibody , 1989, Environmental and molecular mutagenesis.
[17] M. Fenech,et al. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. , 1989, Mutagenesis.
[18] R. Baker,et al. Initiating carcinogen, triethylenemelamine, induces micronuclei in skin target cells , 1989, Environmental and molecular mutagenesis.
[19] A. Tates,et al. The present state of the automated micronucleus test for lymphocytes. , 1990, International journal of radiation biology.
[20] J. Heddle,et al. Concurrent detection of gene mutations and chromosomal aberrations induced in vivo in somatic cells. , 1990, Mutagenesis.
[21] Y. Shibamoto,et al. Tumor radiosensitivity prediction by the cytokinesis-block micronucleus assay. , 1991, Radiation research.
[22] K. Ono,et al. A method for the selective measurement of the radiosensitivity of quiescent cells in solid tumors--combination of immunofluorescence staining to BrdU and micronucleus assay. , 1991, Radiation research.
[23] A. Morley,et al. The cytokinesis-block micronucleus assay as a biological dosimeter in spleen and peripheral blood lymphocytes of the mouse following acute whole-body irradiation. , 1991, Mutation research.
[24] H. Norppa,et al. Induction of micronuclei and anaphase aberrations by cytochalasin B in human lymphocyte cultures. , 1991, Mutation research.
[25] S. Venitt,et al. Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells. , 1992, Carcinogenesis.
[26] R. Marcos,et al. A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes. , 1992, Mutagenesis.
[27] M. Fenech,et al. Conversion of excision‐repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes , 1992, Environmental and molecular mutagenesis.
[28] P. Castelain,et al. Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei. , 1993, Mutagenesis.
[29] The use of fluorescence in situ hybridization for the detection of aneugens in cytokinesis-blocked mouse splenocytes. , 1993, Mutagenesis.
[30] J. Savage. Update on target theory as applied to chromosomal aberrations , 1993, Environmental and molecular mutagenesis.
[31] H. Thierens,et al. Scoring of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes by automated image analysis. , 1994, Cytometry.
[32] A. Zijno,et al. Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridization with a centromeric DNA probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin B. , 1994, Mutagenesis.
[33] J. Surrallés,et al. The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes. , 1994, Mutagenesis.
[34] M. Fenech,et al. Micronucleus induction in cytokinesis‐blocked mouse bone marrow cells in vitro following in vivo exposure to x‐irradiation and cyclophosphamide , 1994, Environmental and molecular mutagenesis.
[35] M. Schmid,et al. Exclusion of specific human chromosomes into micronuclei by 5-azacytidine treatment of lymphocyte cultures. , 1994, Experimental cell research.
[36] C. Unger,et al. Gamma-irradiation-induced micronuclei from mouse hepatoma cells accumulate high levels of the tumor suppressor protein p53. , 1994, Cancer research.
[37] J Rinaldi,et al. A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians. , 1995, Carcinogenesis.
[38] R. Marcos,et al. The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair. , 1995, Mutation research.
[39] A Elhajouji,et al. Indications for a threshold of chemically‐induced aneuploidy in vitro in human lymphocytes , 1995, Environmental and molecular mutagenesis.
[40] E. Parry,et al. Procedures for the detection of chemically induced aneuploidy: recommendations of a UK Environmental Mutagen Society working group. , 1995, Mutagenesis.
[41] C. Streffer,et al. Image processing algorithms for the automated micronucleus assay in binucleated human lymphocytes. , 1995, Cytometry.
[42] D. Eastmond,et al. A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro. , 1997, Mutation research.
[43] M. Fenech,et al. The advantages and disadvantages of the cytokinesis-block micronucleus method. , 1997, Mutation research.
[44] M. Kirsch‐Volders,et al. The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. , 1997, Mutation research.
[45] M. Kirsch‐Volders,et al. Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. , 1997, Mutagenesis.
[46] A Elhajouji,et al. Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay. , 1998, Mutagenesis.
[47] S. Roberts,et al. Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? , 1998, British Journal of Cancer.
[48] P. Chumakov,et al. Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation. , 1998, Journal of cell science.
[49] G. Wahl,et al. Selective Entrapment of Extrachromosomally Amplified DNA by Nuclear Budding and Micronucleation during S Phase , 1998, The Journal of cell biology.
[50] W Frieauff,et al. Automatic analysis of the in vitro micronucleus test on V79 cells. , 1998, Mutation research.
[51] M. Fenech,et al. The HUman MicroNucleus Project--An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. , 1999, Mutation research.
[52] M Fenech,et al. Necrosis, apoptosis, cytostasis and DNA damage in human lymphocytes measured simultaneously within the cytokinesis-block micronucleus assay: description of the method and results for hydrogen peroxide. , 1999, Mutagenesis.
[53] C. Tanzarella,et al. Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes. , 1999, Mutagenesis.
[54] W. von der Hude,et al. Chemically induced micronucleus formation in V79 cells--comparison of three different test approaches. , 1999, Mutation research.
[55] E. Rassart,et al. Biomarkers of DNA damage in marine mammals. , 1999, Mutation research.
[56] T. Sofuni,et al. Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU). , 1999, Mutagenesis.
[57] M. Fenech,et al. A mathematical model of the in vitro micronucleus assay predicts false negative results if micronuclei are not specifically scored in binucleated cells or in cells that have completed one nuclear division. , 2000, Mutagenesis.