In Vivo Deep Penetration Three-Photon Imaging of Mouse Brain through an Unthinned, Intact Skull
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In vivo images of the mouse brain were recorded through an unthinned, intact skull using three-photon fluorescence microscopy at 1700 nm. Images of brain vasculature 900 μm below the surface of the skull were obtained.
[1] W. Gan,et al. Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex , 2007, Nature Neuroscience.
[2] D. Kobat,et al. In vivo two-photon microscopy to 1.6-mm depth in mouse cortex. , 2011, Journal of biomedical optics.
[3] David Kleinfeld,et al. Chronic optical access through a polished and reinforced thinned skull. , 2010, Nature methods.
[4] Jaime Grutzendler,et al. Thinned-skull cranial window technique for long-term imaging of the cortex in live mice , 2010, Nature Protocols.