A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).
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J. Mellors | Y. Cheng | E. Tramontano | G. Piras | D. Medina | G. Im | C. J. González | H. Z. Bazmi | G. Dutschman | S. Winkler | Y. Cheng