The individual and socioeconomic impact of osteoarthritis

Osteoarthritis (OA) is a highly prevalent, disabling disease, with a commensurate tremendous individual and socioeconomic burden. This Perspectives article focuses on the burden of OA for the individual, the health-care system and society, to draw attention to the magnitude of the current problem with some reference to projected figures. We have an urgent opportunity to make fundamental changes to the way we care for individuals with OA that will have an effect upon the direct and indirect costs of this disease. By focusing on the burden of this prevalent, disabling, and costly disease, we hope to highlight the opportunity for shifts in health-care policy towards prevention and chronic-disease management.

[1]  D. Hunter,et al.  The symptoms of osteoarthritis and the genesis of pain. , 2009, The Medical clinics of North America.

[2]  Edward H. Yelin,et al.  National and state medical expenditures and lost earnings attributable to arthritis and other rheumatic conditions--United States, 2003. , 2007, MMWR. Morbidity and mortality weekly report.

[3]  S. Kurtz,et al.  Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. , 2007, The Journal of bone and joint surgery. American volume.

[4]  C. Helmick,et al.  Projections of US prevalence of arthritis and associated activity limitations. , 2006, Arthritis and rheumatism.

[5]  D. Felson,et al.  An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. , 1998, Arthritis and rheumatism.

[6]  A. Anis,et al.  The Indirect Costs of Arthritis Resulting From Unemployment, Reduced Performance, and Occupational Changes While at Work , 2006, Medical care.

[7]  P. Wolf,et al.  The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. , 1994, American journal of public health.

[8]  R. Shrestha,et al.  Modelling the cost of ill health in Health&WealthMOD (Version II): lost labour force participation, income and taxation, and the impact of disease prevention , 2010 .

[9]  P. Dieppe,et al.  Pathogenesis and management of pain in osteoarthritis , 2005, The Lancet.

[10]  B. Sathiyasekaran.  Population-based cohort study of injuries. , 1996, Injury.

[11]  David T Felson,et al.  Prevalence of symptomatic hand osteoarthritis and its impact on functional status among the elderly: The Framingham Study. , 2002, American journal of epidemiology.

[12]  E. Batlle-Gualda,et al.  Economic burden of knee and hip osteoarthritis in Spain. , 2009, Arthritis and rheumatism.

[13]  René Rizzoli,et al.  Health economics in the field of osteoarthritis: an expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). , 2013, Seminars in arthritis and rheumatism.

[14]  L. March,et al.  10 Economics of osteoarthritis: a global perspective , 1997 .

[15]  G. Hawker.  Experiencing painful osteoarthritis: what have we learned from listening? , 2009, Current opinion in rheumatology.

[16]  D. Hunter,et al.  Emerging drugs for osteoarthritis , 2011, Expert opinion on emerging drugs.

[17]  Bernadette A. Thomas,et al.  Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[18]  A. Belanger,et al.  The Framingham study. , 1976, British medical journal.

[19]  Bernadette A. Thomas,et al.  Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[20]  E. Badley,et al.  Revisiting arthritis prevalence projections--it's more than just the aging of the population. , 2006, The Journal of rheumatology.

[21]  J. Katz,et al.  Impact of Knee Osteoarthritis on Health Care Resource Utilization in a US Population-Based National Sample , 2010, Medical Care.

[22]  J. Rizzo,et al.  Osteoarthritis and Absenteeism Costs: Evidence From US National Survey Data , 2010, Journal of occupational and environmental medicine.

[23]  Rowland W Chang,et al.  The costs of arthritis. , 2003, Arthritis and rheumatism.

[24]  M. Harrison.  A Global Perspective , 2015, Bulletin of the history of medicine.

[25]  D. Dunlop,et al.  Arthritis prevalence and activity limitations in older adults. , 2001, Arthritis and rheumatism.

[26]  L. March,et al.  Improving care for people with osteoarthritis of the hip and knee: How has national policy for osteoarthritis been translated into service models in Australia? , 2011, International journal of rheumatic diseases.

[27]  G. Hawker,et al.  The economic burden of disabling hip and knee osteoarthritis (OA) from the perspective of individuals living with this condition. , 2005, Rheumatology.

[28]  C. Le Pen,et al.  Financial cost of osteoarthritis in France. The "COART" France study. , 2005, Joint, bone, spine : revue du rhumatisme.

[29]  A D Paltiel,et al.  Disease-modifying drugs for knee osteoarthritis: can they be cost-effective? , 2009, Osteoarthritis and cartilage.

[30]  Peter Croft,et al.  Factors associated with restricted mobility outside the home in community-dwelling adults ages fifty years and older with knee pain: an example of use of the International Classification of Functioning to investigate participation restriction. , 2007, Arthritis and rheumatism.

[31]  L. March,et al.  Economics of osteoarthritis: a global perspective. , 1997, Bailliere's clinical rheumatology.

[32]  Rochelle P. Walensky,et al.  Impact of Obesity and Knee Osteoarthritis on Morbidity and Mortality in Older Americans , 2011, Annals of Internal Medicine.

[33]  R. Shrestha,et al.  Economic impacts of illness in older workers: quantifying the impact of illness on income, tax revenue and government spending , 2011, BMC public health.

[34]  M. Englund,et al.  Risk of sick leave and disability pension in working-age women and men with knee osteoarthritis , 2012, Annals of the rheumatic diseases.

[35]  Atlanta,et al.  Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. , 2008, Arthritis and rheumatism.

[36]  D. Beaton,et al.  Productivity Loss Due to Presenteeism Among Patients with Arthritis: Estimates from 4 Instruments , 2010, The Journal of Rheumatology.

[37]  R. Shrestha,et al.  The personal and national costs of lost labour force participation due to arthritis: an economic study , 2013, BMC Public Health.

[38]  S. Reichenbach,et al.  All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study , 2011, BMJ : British Medical Journal.

[39]  F. Salaffi,et al.  Direct and indirect costs of osteoarthritis of the knee. , 2004, Clinical and experimental rheumatology.

[40]  A. Earnest,et al.  Chronic disease and labour force participation among older Australians , 2008, The Medical journal of Australia.

[41]  T. Ferris,et al.  Options for slowing the growth of health care costs. , 2008, The New England journal of medicine.

[42]  G. Hawker,et al.  The multidimensionality of sleep quality and its relationship to fatigue in older adults with painful osteoarthritis. , 2010, Osteoarthritis and cartilage.

[43]  M. Lungren,et al.  Physician self-referral: frequency of negative findings at MR imaging of the knee as a marker of appropriate utilization. , 2013, Radiology.

[44]  D. Hunter,et al.  Lower extremity osteoarthritis management needs a paradigm shift , 2011, British Journal of Sports Medicine.

[45]  C. Helmick,et al.  Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. , 1998, Arthritis and rheumatism.

[46]  Hai Fang,et al.  Insurer and out-of-pocket costs of osteoarthritis in the US: evidence from national survey data. , 2009, Arthritis and rheumatism.

[47]  Prevalence and impact of chronic joint symptoms--seven states, 1996. , 1998, MMWR. Morbidity and mortality weekly report.

[48]  M. Suarez‐Almazor,et al.  Understanding the pain experience in hip and knee osteoarthritis--an OARSI/OMERACT initiative. , 2008, Osteoarthritis and cartilage.

[49]  S. Gabriel,et al.  Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. , 2008, Arthritis and rheumatism.