Noninvasive Assessment of Atrioventricular Nodal Function: Effect of Rate‐Control Drugs during Atrial Fibrillation

During atrial fibrillation (AF), conventional electrophysiological techniques for assessment of refractory period or conduction velocity of the atrioventricular (AV) node cannot be used. We aimed at evaluating changes in AV nodal properties during administration of tecadenoson and esmolol using a novel ECG‐based method.

[1]  Valentina D. A. Corino,et al.  Atrioventricular nodal function during atrial fibrillation: Model building and robust estimation , 2013, Biomed. Signal Process. Control..

[2]  Wojciech Zareba,et al.  Association between Atrial Fibrillatory Rate and Heart Rate Variability in Patients with Atrial Fibrillation and Congestive Heart Failure , 2013, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[3]  Valentina D. A. Corino,et al.  An Atrioventricular Node Model for Analysis of the Ventricular Response During Atrial Fibrillation , 2011, IEEE Transactions on Biomedical Engineering.

[4]  Francisco Castells,et al.  Role of the Atrial Rate as a Factor Modulating Ventricular Response during Atrial Fibrillation , 2010, Pacing and clinical electrophysiology : PACE.

[5]  J. Fisher Coronary Sinus Left Ventricular Leads: Endocardial or Epicardial? , 2010, Pacing and clinical electrophysiology : PACE.

[6]  P. Macfarlane,et al.  The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. , 2006, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[7]  A. Bollmann,et al.  Analysis of the Surface Electrocardiogram for Monitoring and Predicting Antiarrhythmic Drug Effects in Atrial Fibrillation , 2004, Cardiovascular Drugs and Therapy.

[8]  A. Kadish,et al.  Termination of paroxysmal supraventricular tachycardia by tecadenoson (CVT-510), a novel A1-adenosine receptor agonist. , 2003, Journal of the American College of Cardiology.

[9]  F. Morady,et al.  Effects of Diltiazem and Esmolol on Cycle Length and Spontaneous Conversion of Atrial Fibrillation , 2002, Journal of cardiovascular pharmacology and therapeutics.

[10]  A. Kadish,et al.  Electrophysiologic Effects of a Novel Selective Adenosine A1 Agonist (CVT-510) on Atrioventricular Nodal Conduction in Humans , 2001, Journal of cardiovascular pharmacology and therapeutics.

[11]  R. Lum,et al.  A comparison of an A1 adenosine receptor agonist (CVT‐510) with diltiazem for slowing of AV nodal conduction in guinea‐pig , 1999, British journal of pharmacology.

[12]  A. Frigy,et al.  The efficacy of sublingual verapamil in controlling rapid ventricular rate in chronic atrial fibrillation. , 1998, Romanian journal of internal medicine = Revue roumaine de medecine interne.

[13]  L. Sörnmo,et al.  Non-invasive assessment of the atrial cycle length during atrial fibrillation in man: introducing, validating and illustrating a new ECG method. , 1998, Cardiovascular research.

[14]  C. Tai,et al.  Effects of antiarrhythmic drugs on variability of ventricular rate and exercise performance in chronic atrial fibrillation complicated with ventricular arrhythmias. , 1998, International journal of cardiology.

[15]  P. Gillette,et al.  Different Effects of Flecainide on Atrioventricular Conduction Properties in the Adult and Immature Rabbit Heart , 1997, Cardiovascular Drugs and Therapy.

[16]  H. Tritthart,et al.  Rate-dependent effects of ajmaline and propafenone on atrioventricular conduction. , 1996, European journal of pharmacology.

[17]  R. Arora,et al.  Comparison of electrophysiologic effects and efficacy of single-dose intravenous and long-term oral amiodarone therapy in patients with AV nodal reentrant tachycardia. , 1996, Indian heart journal.

[18]  G. Kay,et al.  Differential Effect of Esmolol on the Fast and Slow AV Nodal Pathways in Patients with AV Nodal Reentrant Tachycardia , 1994, Journal of cardiovascular electrophysiology.

[19]  S. Nattel,et al.  Frequency-dependent effects of diltiazem on the atrioventricular node during experimental atrial fibrillation. , 1989, Circulation.

[20]  L. Horowitz,et al.  Electrophysiology of esmolol. , 1985, The American journal of cardiology.

[21]  F. Roberge,et al.  Relation between the minimum RR interval during atrial fibrillation and the functional refractory period of the AV junction. , 1974, Cardiovascular research.

[22]  A. Katz,et al.  INO-8875, a Highly-Selective A1 Adenosine Receptor Agonist: Evaluation of Chronotropic, Dromotropic and Hemodynamic Effects in Rats. , 2010, The Journal of pharmacology and experimental therapeutics.

[23]  Frida Sandberg,et al.  Frequency Tracking of Atrial Fibrillation using Hidden Markov Models , 2006, 2006 International Conference of the IEEE Engineering in Medicine and Biology Society.

[24]  Leif Sörnmo,et al.  Spatiotemporal QRST cancellation techniques for analysis of atrial fibrillation , 2001, IEEE Transactions on Biomedical Engineering.

[25]  S. Sakata,et al.  Circadian rhythms of atrioventricular conduction properties in chronic atrial fibrillation with and without heart failure. , 1998, Journal of the American College of Cardiology.