Bone morphogenetic proteins in multiple sclerosis: Role in neuroinflammation
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[1] J. Ukropec,et al. Bmp4 Promotes a Brown to White-like Adipocyte Shift. , 2016, Cell reports.
[2] M. Sospedra,et al. Immunology of Multiple Sclerosis , 2016, Seminars in Neurology.
[3] S. M. Chuva de Sousa Lopes,et al. BMP-SMAD signaling: From pluripotent stem cells to cardiovascular commitment. , 2016, Cytokine & growth factor reviews.
[4] Jill A Hollenbach,et al. The immunogenetics of multiple sclerosis: A comprehensive review. , 2015, Journal of autoimmunity.
[5] R. Autio,et al. Bone Morphogenetic Protein‐2 Induces Donor‐Dependent Osteogenic and Adipogenic Differentiation in Human Adipose Stem Cells , 2015, Stem cells translational medicine.
[6] Manuel A. Friese,et al. Immunopathology of multiple sclerosis , 2015, Nature Reviews Immunology.
[7] Victor G. Martinez,et al. The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis , 2015, PloS one.
[8] R. Harland,et al. Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation , 2015, Development.
[9] J. Ioannidis,et al. Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses , 2015, The Lancet Neurology.
[10] A. Lo,et al. Treatment of progressive multiple sclerosis: what works, what does not, and what is needed , 2015, The Lancet Neurology.
[11] J. Grinspan. Bone Morphogenetic Proteins: Inhibitors of Myelination in Development and Disease. , 2015, Vitamins and hormones.
[12] T. Mueller. Mechanisms of BMP-Receptor Interaction and Activation. , 2015, Vitamins and hormones.
[13] A. Kurczewska,et al. Modulation of bone morphogenic protein signaling in T-cells for cancer immunotherapy , 2014, Journal of immunotoxicology.
[14] Jeffrey A. Cohen,et al. Defining the clinical course of multiple sclerosis: the 2013 revisions. , 2014, Neurology.
[15] M. Costanzi,et al. Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids , 2014, Front. Cell. Neurosci..
[16] M C Sogayar,et al. Bone Morphogenetic Proteins , 2014, Journal of dental research.
[17] A. Karni,et al. Elevated and dysregulated bone morphogenic proteins in immune cells of patients with relapsing–remitting multiple sclerosis , 2013, Journal of Neuroimmunology.
[18] M. Pirinen,et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis , 2013, Nature Genetics.
[19] J. Lünemann,et al. The initiation and prevention of multiple sclerosis , 2012, Nature Reviews Neurology.
[20] L. P. Chen,et al. Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model , 2012, Neuroscience.
[21] M. Costanzi,et al. Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone , 2012, Front. Neurosci..
[22] S. Vukicevic,et al. BMP signaling in rats with TNBS-induced colitis following BMP7 therapy. , 2012, American journal of physiology. Gastrointestinal and liver physiology.
[23] I. Konishi,et al. Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T‐cell activation and differentiation , 2012, European journal of immunology.
[24] A. Zapata,et al. Expression of BMPRIA on human thymic NK cell precursors: role of BMP signaling in intrathymic NK cell development. , 2012, Blood.
[25] K. Sato,et al. BMP2, BMP4, noggin, BMPRIA, BMPRIB, and BMPRII are differentially expressed in the adult rat spinal cord , 2012, Neuroscience.
[26] S. Lawler,et al. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity. , 2011, Brain : a journal of neurology.
[27] J. Myklebust,et al. Bone morphogenetic proteins inhibit CD40L/IL‐21‐induced Ig production in human Bcells: Differential effects of BMP‐6 and BMP‐7 , 2011, European journal of immunology.
[28] A. Karni,et al. Low and dysregulated production of follistatin in immune cells of relapsing–remitting multiple sclerosis patients , 2011, Journal of Neuroimmunology.
[29] Simon C. Potter,et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis , 2011, Nature.
[30] H. Hartung,et al. Enhancing remyelination in disease--can we wrap it up? , 2011, Brain : a journal of neurology.
[31] T. Walz,et al. Latent TGF-β structure and activation , 2011, Nature.
[32] P. Jin,et al. RNA-Binding Protein FXR2 Regulates Adult Hippocampal Neurogenesis by Reducing Noggin Expression , 2011, Neuron.
[33] T. Kilpatrick,et al. Remyelination Is Altered by Bone Morphogenic Protein Signaling in Demyelinated Lesions , 2011, The Journal of Neuroscience.
[34] N. Bornstein,et al. Reduced production of noggin by immune cells of patients with relapsing–remitting multiple sclerosis , 2011, Journal of Neuroimmunology.
[35] T. Kilpatrick,et al. Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone‐induced demyelination , 2010, Journal of neurochemistry.
[36] F. Gage,et al. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. , 2010, Cell stem cell.
[37] G. Ming,et al. Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination , 2010, Nature Neuroscience.
[38] L. Kappos,et al. Altered expression of miR‐17‐5p in CD4+ lymphocytes of relapsing–remitting multiple sclerosis patients , 2010, European journal of immunology.
[39] C. Lindsley,et al. In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. , 2010, ACS chemical biology.
[40] S. Vukicevic,et al. Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity* , 2010, The Journal of Biological Chemistry.
[41] S. Zheng,et al. Synergistic effect of TGF‐β superfamily members on the induction of Foxp3+ Treg , 2009, European journal of immunology.
[42] S. Takai,et al. TGF-β superfamily enhances the antigen-induced IFN-γ production by effector/memory CD8+ T cells , 2009 .
[43] S. Mundlos,et al. Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN , 2009, PLoS genetics.
[44] Hans-Peter Lenhof,et al. Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls , 2009, PloS one.
[45] J. Christian,et al. Site-specific Cleavage of BMP4 by Furin, PC6, and PC7* , 2009, The Journal of Biological Chemistry.
[46] J. A. Lozano,et al. Differential Micro RNA Expression in PBMC from Multiple Sclerosis Patients , 2009, PloS one.
[47] J. García-Verdugo,et al. Immune Regulatory Neural Stem/Precursor Cells Protect from Central Nervous System Autoimmunity by Restraining Dendritic Cell Function , 2009, PloS one.
[48] Elizabeth J. Robertson,et al. Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo , 2009, Nature Reviews Molecular Cell Biology.
[49] Xiao-Fan Wang,et al. Signaling cross-talk between TGF-β/BMP and other pathways , 2009, Cell Research.
[50] Robin J. M. Franklin,et al. Remyelination in the CNS: from biology to therapy , 2008, Nature Reviews Neuroscience.
[51] F. Luyten,et al. Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease , 2008, Arthritis research & therapy.
[52] A. Prat,et al. The activation and physiological functions of the proprotein convertases. , 2008, The international journal of biochemistry & cell biology.
[53] C. Mummery,et al. Adult Neurogenesis Requires Smad4-Mediated Bone Morphogenic Protein Signaling in Stem Cells , 2008, The Journal of Neuroscience.
[54] Charles C Hong,et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. , 2008, Nature chemical biology.
[55] S. Whittemore,et al. Bone Morphogenetic Protein Signaling and Olig1/2 Interact to Regulate the Differentiation and Maturation of Adult Oligodendrocyte Precursor Cells , 2007, Stem cells.
[56] Li-Xin Xiang,et al. Bone morphogenetic protein. , 2007, Biochemical and biophysical research communications.
[57] C. Minetti,et al. Potential drug targets within bone morphogenetic protein signaling pathways. , 2007, Current opinion in pharmacology.
[58] A. Zapata,et al. Bone morphogenetic protein‐2/4 signalling pathway components are expressed in the human thymus and inhibit early T‐cell development , 2007, Immunology.
[59] Ryan M. Anderson,et al. Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.
[60] E. Thonar,et al. Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate , 2006, Arthritis research & therapy.
[61] E. Frohman,et al. Multiple sclerosis--the plaque and its pathogenesis. , 2006, The New England journal of medicine.
[62] J. Massagué,et al. Smad transcription factors. , 2005, Genes & development.
[63] J. Masjuán,et al. Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS. , 2005, The Journal of clinical investigation.
[64] J. Myklebust,et al. BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1 , 2005, BMC Immunology.
[65] J. Golden,et al. Oligodendrocyte maturation is inhibited by bone morphogenetic protein , 2004, Molecular and Cellular Neuroscience.
[66] J. Smolen,et al. Arthritis Induces Lymphocytic Bone Marrow Inflammation and Endosteal Bone Formation , 2004 .
[67] Clare Baecher-Allan,et al. Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis , 2004, The Journal of experimental medicine.
[68] F. Luyten,et al. Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. , 2003, Arthritis and rheumatism.
[69] Markus Affolter,et al. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin , 2002, Nature.
[70] Anja Nohe,et al. The Mode of Bone Morphogenetic Protein (BMP) Receptor Oligomerization Determines Different BMP-2 Signaling Pathways* , 2002, The Journal of Biological Chemistry.
[71] R. Rudick,et al. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. , 2002, The New England journal of medicine.
[72] J. Haines,et al. Genetic basis for clinical expression in multiple sclerosis. , 2002, Brain : a journal of neurology.
[73] T. Nakayama,et al. The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor. , 2001, Genes & development.
[74] M. Luskin,et al. Retroviral manipulation of the expression of bone morphogenetic protein receptor Ia by SVZa progenitor cells leads to changes in their p19INK4d expression but not in their neuronal commitment , 2001, International Journal of Developmental Neuroscience.
[75] C. Lucchinetti,et al. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. , 2001, Trends in molecular medicine.
[76] J. García-Verdugo,et al. Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis , 2000, Neuron.
[77] Jeffrey A. Golden,et al. Stage-specific effects of bone morphogenetic proteins on the oligodendrocyte lineage. , 2000, Journal of neurobiology.
[78] U. Brehm,et al. The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis. , 2000, Journal of neural transmission. Supplementum.
[79] J. Dick,et al. Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells , 1999, The Journal of experimental medicine.
[80] C. Heldin,et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling , 1997, Nature.
[81] K. Miyazono,et al. Smad6 inhibits signalling by the TGF-β superfamily , 1997, Nature.
[82] M. Mehler,et al. Bone Morphogenetic Proteins Induce Astroglial Differentiation of Oligodendroglial–Astroglial Progenitor Cells , 1997, The Journal of Neuroscience.
[83] R. Harland,et al. The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4 , 1996, Cell.
[84] A. Bradley,et al. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. , 1995, Genes & development.
[85] J. Massagué,et al. GS domain mutations that constitutively activate T beta R‐I, the downstream signaling component in the TGF‐beta receptor complex. , 1995, The EMBO journal.
[86] J. Strominger,et al. Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein , 1995, Cell.
[87] V. Rosen,et al. Novel regulators of bone formation: molecular clones and activities. , 1988, Science.
[88] V. Rosen,et al. Purification and characterization of other distinct bone-inducing factors. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[89] M. Urist,et al. Bone: Formation by Autoinduction , 1965, Science.
[90] E. Kabat,et al. AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS. , 1942, The Journal of clinical investigation.