Serious consequences of a sore throat.

Lemierre's syndrome, caused by Fusobacterium necrophorum, is a potentially fatal sequelae of a sore throat characterised by septicaemia, internal jugular vein thrombophlebitis and metastatic abscesses. The Chief Medical Officer reported in February 2001 that the incidence is increasing. Two cases seen in one year, with different presentations, are reported. The first patient presented with sepsis, jaundice, hepatic abscesses and portal vein/superior mesenteric vein thrombosis, whilst the second presented with sepsis, sore throat and internal jugular vein thrombophlebitis. Both patients were treated with antibiotics and anticoagulants with a favourable outcome.

[1]  C. Pokorny,et al.  Septic portal vein thrombosis due to Fusobacterium necrophorum. , 1999, Australian and New Zealand journal of medicine.

[2]  L. Hagelskjær,et al.  Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark 1990–1995 , 1998, European Journal of Clinical Microbiology and Infectious Diseases.

[3]  K. Ratzan,et al.  A young woman with a sore throat, septicaemia, and respiratory failure , 1997, The Lancet.

[4]  J. Schreiber,et al.  Lemierre's syndrome in adolescent children--anaerobic sepsis with internal jugular vein thrombophlebitis following pharyngitis. , 1995, Pediatrics.

[5]  I. Brook Infections caused by beta-lactamase-producing Fusobacterium spp. in children. , 1993, The Pediatric infectious disease journal.

[6]  P. Fardy,et al.  The Lemierre Syndrome: Suppurative Thrombophlebitis of the Internal Jugular Vein Secondary to Oropharyngeal Infection , 1989, Medicine.

[7]  J. Goldhagen,et al.  Suppurative thrombophlebitis of the internal jugular vein: report of three cases and review of the pediatric literature. , 1988, The Pediatric infectious disease journal.

[8]  J. Embree,et al.  Hepatic abscesses in a child caused by Fusobacterium necrophorum. , 1988, The Pediatric infectious disease journal.

[9]  J. Goldenring,et al.  Primary Liver Abscesses in Children and Adolescents , 1986, Clinical pediatrics.

[10]  T. Bilfinger,et al.  Pyogenic Liver Abscesses in Nonimmunocompromised Children , 1986, Southern medical journal.

[11]  J. Sabbaj Anaerobes in liver abscess. , 1984, Reviews of infectious diseases.

[12]  A. Lemierre ON CERTAIN SEPTICÆMIAS DUE TO ANAEROBIC ORGANISMS , 1936 .